PhD student at MPI Marburg @mpi_marburg🕺 Interested in electron transfer proteins @Rebeleinlab

Joined August 2021
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I am excited to share that my first research paper is now available online at @mBio: doi.org/10.1128/mbio.03314-2…. We explore the role of #ferredoxins (Fds) in nitrogen (N2) fixation by #nitrogenases (N2ases), the only enzymes to convert atmospheric N2 into bioavailable ammonia (NH3).
Paper Alert 🚀! Exciting findings from @RebeleinLab! Two proteins are crucial for electron supply of Fe #Nitrogenase: new targets for improving #biocatalysis in #sustainable #fertilizer and carbon compound synthesis. Check out our press article: mpi-marburg.mpg.de/1361203/2…
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Holly Addison retweeted
Dear nitrogenase lovers: have a look at our BioRxiv prepublication. Ana Maciel, Jessica Soares, ..., Antonio Pierik and Johannes Rebelein proudly present that Methylthio-alkane reductases use nitrogenase metalloclusters for carbon-sulfur bond cleavage. doi.org/10.1101/2024.10.19.6…

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I am excited to share that my first research paper is now available online at @mBio: doi.org/10.1128/mbio.03314-2…. We explore the role of #ferredoxins (Fds) in nitrogen (N2) fixation by #nitrogenases (N2ases), the only enzymes to convert atmospheric N2 into bioavailable ammonia (NH3).
Paper Alert 🚀! Exciting findings from @RebeleinLab! Two proteins are crucial for electron supply of Fe #Nitrogenase: new targets for improving #biocatalysis in #sustainable #fertilizer and carbon compound synthesis. Check out our press article: mpi-marburg.mpg.de/1361203/2…
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Apologies there was a typo, journal is @mbiojournal
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Replying to @mbio
I would like to thank the co-authors on this publication, Dr. Timo Glatter and @KaHochberg. Also, a special thanks to my PhD supervisor @RebeleinLab!
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Replying to @mbio
Both Fds are excellent targets for bioengineering the e- flux to the Fe-N2ase with aims to further increase the conversion of N2to NH3.
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Replying to @mbio
We found that 2 distinct Fds with different redox centres are essential for N2-fixation by the Fe-N2ase, though surprisingly, our results suggest the 2 Fds likely have separate roles in N2-fixation.
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Replying to @mbio
We investigate the unknown e- transfer to the Fe-N2ase and tackle the question whether Fds are specific or redundant in the e- transport to the Fe-N2ase in Rhodobacter capsulatus.
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Our manuscript is now online @Bioarchivepreprint! We explore the role of #ferredoxins (Fds) in nitrogen (N2) fixation via #nitrogenases (N2ases), the only enzymes to convert atmospheric N2 into bioavailable ammonia (NH3) and CO2 directly to hydrocarbons. dlvr.it/Szs2gs

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In conclusion, we established that 2 distinct Fds with different redox centres are essential for Fe-N2ase mediated N2-fixation. These Fds are excellent targets for bioengineering aiming to further increase the conversion of N2 to NH3and CO2 to hydrocarbons by the Fe-N2ase.
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Finally, I would like to thank the co-authors on this publication, Dr. Timo Glatter and @KaHochberg. Also, a special thanks to my PhD supervisor @RebeleinLab. Thanks for reading 😀
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Holly Addison retweeted
Great talk by @HollyGAddison about the electron transport to the iron #nitrogenase by #ferredoxins #VAAM2023
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