Teaching point:
If tidal volumes are constant between the two measurements, the PEEP associated with the best static compliance is the one associated with the lowest driving pressure. Titrating to best static compliance vs to driving pressure becomes semantics.
However, if tidal volumes change between measurements, you can’t look at the driving pressure alone (the driving pressure is associated with BOTH static compliance AND tidal volume).
If your patient is on Pressure Control, like the one above, and the increase in PEEP worsens static compliance, tidal volumes will drop for the same applied inspiratory pressure. In a case like this, you MUST look at the static compliance!
We did insp and exp holds to calculate static compliance and got:
At a totPEEP of 12: 317/(32-12) = ~16ml/cmH2O
At a totPEEP of 15: 272/(34-15) = ~14ml/cmH2O
Since compliance was better at a PEEP of 12, we kept it as our ideal PEEP.