PhD student at UPenn studying the transcription factor RUNX1 and its role is specifying endothelial cells as hemogenic in the Speck Lab @LabSpeck 👩🏼🔬🔬🧫🧬
Have you ever wondered what makes an endothelial cell permissive to be reprogrammed by RUNX1 to a blood cell? Well I have the answer for you - see article and 🧵genesdev.cshlp.org/content/e…
Have you ever wondered what makes an endothelial cell permissive to be reprogrammed by RUNX1 to a blood cell? Well I have the answer for you - see article and 🧵genesdev.cshlp.org/content/e…
This work highlights the importance of TGFb target genes in EHT as well as the cooperativity of RUNX1, AP-1, and SMAD factors in activating these TGFb target genes that are involved in the morphological component of EHT
Excited to finally share what I've been working on the last few years! This work wouldn't have been possible without the amazing help of @KaiTanLab1 , @cdktmw , @penggao8 , @hb8812 , @Melike_Lak , @RafiiShahin, @LabSpeck & twitter-less Amanada Yzaguirre