Information about the IntFOLD server and its components. Predicted protein structures and functions from sequences with built-in quality estimates & refinement.
Joined March 2021
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We have moved to Bluesky:
bsky.app/profile/intfold.bsk…
Main link for IntFOLD server: reading.ac.uk/bioinf/IntFOLD…
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Our paper on the performance of ModFOLDdock2 at #CASP16 @ReadingBioSci
onlinelibrary.wiley.com/doi/…
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We used IntFOLD, and MultiFOLD to model interactions between Cx62 and calpain-1: "Inter-platelet communication driving thrombus formation is regulated by extracellular calpain-1 cleavage of connexin 62" | Haematologica haematologica.org/article/vi…
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Our new paper is out: Prediction and quality assessment of protein quaternary structure models using the MultiFOLD2 and ModFOLDdock2 servers academic.oup.com/nar/article… @ReadingBioSci
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IntFOLD - find us on Bluesky @intfold.bsky.social retweeted
16 Dec 2023
Benchmarking of AlphaFold2 accuracy self-estimates as empirical quality measures and model ranking indicators and their comparison ... biorxiv.org/cgi/content/shor… #biorxiv_bioinfo
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IntFOLD - find us on Bluesky @intfold.bsky.social retweeted
28 Jun 2023
Improvement of protein tertiary and quaternary structure predictions using the ReFOLD refinement method and the AlphaFold2 recycling process @RcpAdymn, Nicholas Edmunds, @AhmetGGenc, Shuaa M A Alharbi, @liammcguffin in @BioinfoAdv
doi.org/10.1093/bioadv/vbad0…
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Our new preprint is out: Improvement of protein tertiary and quaternary structure predictions using the ReFOLD4 refinement method and the AlphaFold2 recycling process @ReadingBioSci biorxiv.org/cgi/content/sh… #bioRxiv
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IntFOLD - find us on Bluesky @intfold.bsky.social retweeted
9 Dec 2022
Improvement of protein tertiary and quaternary structure predictions using the ReFOLD4 refinement method and the AlphaFold2 recycling process biorxiv.org/cgi/content/shor… #bioRxiv
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IntFOLD - find us on Bluesky @intfold.bsky.social retweeted
18 Nov 2021
Last night, we took home the 🏆 for Net Zero Strategy of the Year in the Energy Management Awards 2021!
This award places us among the leading public and private sector organisations in the UK for sustainability.
Find out more: rdg.ac/3cr4co1
#PlanetPartners
ALT autumnal trees, bushy with yellow, orange and red leaves, stand between the brutalist URS building and the silver exterior of the library
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IntFOLD - find us on Bluesky @intfold.bsky.social retweeted
Our ReFOLD3 method presentation at ISMB/ECCB 2021 by Recep Adiyaman - 3DSIG @intfold youtu.be/AcdwUPXECwI
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We used IntFOLD, ModFOLD, and ReFOLD for modeling SARS‐CoV2 proteins in the CASP‐commons experiment onlinelibrary.wiley.com/doi/…
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IntFOLD has served ~11,000 unique users from over 100 different countries.
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The IntFOLD website had 99.966% uptime over the last 30 days. The server was briefly unavailable for <15 min on Wed.
We used IntFOLD and MultiFOLD to model interactions between MAP4K4 and striatins: MAP4K4 expression in cardiomyocytes: multiple isoforms, multiple phosphorylations and interactions with striatins portlandpress.com/biochemj/a…
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The server has been improved this week with more rigorous error checking and reporting to users.
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We have now installed some new server hardware. Queues should now be faster to clear, especially over weekends, which tend to be busier.
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IntFOLD version 6 is now publicly available for user testing. Our recently published ModFOLD8 and ReFOLD3 methods are fully integrated with IntFOLD6. reading.ac.uk/bioinf/IntFOLD…
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