1. Remember that any attempt to paint Long Covid as psychogenic in nature deliberately and completely incorrectly biologically decouples SARS-CoV-2 infection from Long Covid. In essence, this rhetoric shifts the causative factor for LC from the virus to the patient's mind.

We’re a primary care practice in Vermont. We implemented a practice-wide protocol screening every patient at every encounter for recent SARS-CoV-2 infection history. What we’re observing in our panel is not consistent with a psychosomatic framework. We’re seeing measurable, objective increases in new-onset hypertension, acute cardiovascular events, new-onset allergic disease, and new-onset type 2 diabetes mellitus, all temporally correlated with infection history. These are not symptom reports. These are clinical findings.

Researchers estimate long COVID could cost the US more than $8 billion by 2027. At least 44 million Americans have reported symptoms, with lost work productivity driving over 90% of the economic burden. fortune.com/2026/05/24/long-…

L0NG C0VID IS QUIETLY WRECKING HEARTS. Maybe time for a recap based on 2026 science. Here’s the comparison for MACE, Stroke, Deadly Clots & overall CV risks: ➡️MACE (heart attack, stroke, heart failure) • Non-COVID: HR 1.0 • COVID-19: 1.8–3.9x • Long COVID: ~4.5x ➡️Stroke (ischemic): • Non-COVID: HR 1.0 • COVID-19: ~2–3x • Long COVID: ~3.5x ➡️Deadly clots (PE / VTE): • Non-COVID: HR 1.0 • COVID-19: ~2–4x • Long COVID: 3.2–4.4x ➡️Overall CV risks: • Non-COVID: baseline • COVID-19: ↑1.5–2.5x (arrhythmias, CAD, HF) • Long COVID: 2–4.5x higher Long COVID adds extra danger beyond regular post-COVID. Risks hit even non-hospitalized patients and last for years. Vax may reduce risks but certainly doesn’t erase it. Absolute risks lower in young/healthy, but serious if older/comorbid. ‼️Today’s evidence shows that while any COVID-19 infection elevates cardiovascular risks, long COVID dramatically amplifies them, making proactive heart monitoring essential for affected patients. Bottom line: Get your heart checked post-Covid19/ LongC0vid and #AvoidSars2 #AvoidReinfections! 🚨C0VID-19/L0NG C0VID are serious CV RISK FACTORS!

SARS-CoV-2 spike protein may directly amplify brain inflammation. ➡️ Researchers found that spike proteins can colocalize with amyloid-β (Aβ) and trigger distinct inflammatory responses in microglia — the brain’s immune cells. ➡️ This raises important questions about potential long-term neurodegenerative consequences of COVID-19. 1/

Endothelial dysfunction and metabolic biomarkers in post-COVID-19 syndrome 🚨A nightmare study for many! FOR EVERYBODY: 9 months after your COVID-19, your blood vessels are STILL damaged, with probably biomarkers to prove it! 1. Study design: German prospective cohort (n=262 adults) compared blood biomarkers ~37 weeks post-SARS-CoV-2 infection (PCS patients recovered) versus uninfected controls. 2. Endothelial dysfunction: - Soluble thrombomodulin (sTM) and lactate dehydrogenase (LDH), two established markers of endothelial (blood-vessel) damage, were significantly elevated in the combined infected group (UOC PCS LIFE Cov ) versus never-infected controls. - So, previously infected individuals had significantly higher soluble thrombomodulin (TM) and lactate dehydrogenase (LDH), independent of PCS diagnosis or fatigue severity. - Critically, there were no significant differences between the PCS group and the LIFE Cov group for these markers. 3. Metabolic disruption: - Clear alterations in arginine biosynthesis and taurine/hypotaurine pathways, indicating impaired nitric-oxide (NO) metabolism with reduced L-arginine and taurine levels. →In plain terms: the vascular damage signal was just as strong in the symptom-free recovered people as in those still suffering from fatigue and other PCS complaints. The same held for the metabolic disruptions (impaired arginine biosynthesis and taurine/hypotaurine pathways linked to nitric-oxide production). 4. Fatigue-specific signal: - High-fatigue PCS patients (top MFI-20 quartile) showed elevated linoleic acid (LA) plus monounsaturated fatty acids oleic (OA) and palmitoleic (PA). →The fatty-acid signature specific to high-fatigue PCS adds a potential severity marker. 5. Notes: - Changes persisted already up to 9 months after infection. - PCS remains symptom-based, but these markers offer objective, measurable signals of underlying vascular and metabolic damage! -The discussion and results treat the observed endothelial and metabolic changes as consequences of a single infection and do not speculate on additive damage from subsequent exposures. - Limitations well noted. ‼️So, COVID-19 leaves detectable, objective blood-vessel and metabolic damage in the bloodstream nearly a year later, even if you feel completely fine and never had Long COVID symptoms. Specific fatty-acid spikes flag severe post-COVID fatigue. The “it’s all in your head” narrative for many post-covid people is directly contradicted by these biomarkers! These findings, solidly backed by prior 2021–2025 evidence, prove that COVID-19 inflicts measurable, persistent endothelial and nitric-oxide metabolic damage up to nearly a year later, even in fully symptom-free survivors, thereby supporting the implementation of routine biomarker screening, but even more importantly: #AvoidSars2 #AvoidReinfections. YOU ARE NOW A CV RISK PATIENT! nature.com/articles/s41598-0…