@IrisJaffeLab profile picture
MCRI Jaffe Lab @IrisJaffeLab

Executive Director of the Molecular Cardiology Research Institute, Physician-Scientist, Eagles fan

Joined November 2018
  • Tweets 201
  • Following 156
  • Followers 360
42 Photos and videos
MCRI Jaffe Lab retweeted
Endothelial Cell News
@endothelialnews
6 Aug 2025
New from the @IrisJaffeLab! 🙌 Ponatinib, a potent anticancer therapy, activates #EndothelialCells and platelets, driving plaque inflammation and death from MI and stroke in mice, mirroring clinical cardiotoxicities in patients with cancer. | @CircAHA 🔗 bit.ly/4mrUhAz
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Tufts Medical Center-Led Study Identifies Safer Path Forward for Cancer Patients at Risk of Heart Disease | ⁦@TuftsMedicalCtr⁩ ⁦@TuftsMedSchool⁩ ⁦@TuftsMCResearch⁩ tuftsmedicine.org/about-us/n…

Tufts Medical Center-Led Study Identifies Safer Path Forward for Cancer Patients at Risk of Heart...

Tufts Medical Center researchers find safer cancer drug option for patients at risk of heart disease, identifying a key mechanism behind treatment-related cardiac events.

tuftsmedicine.org
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Congratulations Tufts MD-PhD student Alec Stepanian and ⁦@TuftsMedicalCtr⁩ Molecular Cardiology research Institute team. ⁦@TuftsMedSchool⁩ ⁦@TuftsMCResearch⁩ pubmed.ncbi.nlm.nih.gov/4076…

Ponatinib, But Not the New Abl-Kinase Inhibitor Asciminib, Activates Platelets, Leukocytes, and...

Ponatinib, a potent anticancer therapy, activates ECs, platelets, and leukocytes, driving plaque inflammation and death from MI and stroke in mice, mirroring clinical cardiotoxicities in patients...

pubmed.ncbi.nlm.nih.gov
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MCRI Jaffe Lab retweeted
Tufts Medical Center@TuftsMedicalCtr
6 May 2025
Members of our Molecular Cardiology Research Institute volunteered with @communityserv yesterday to prep medically tailored meals for people with heart failure, diabetes, kidney disease and HIV. Proud to support patients beyond the lab. #TuftsMedicine @irisjaffelab
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MCRI Jaffe Lab retweeted
Tufts Medical Center Research@TuftsMCResearch
29 Apr 2025
Happening now at #AACR25 @TuftsMedicine @TuftsMedSchool's @IrisJaffeLab presents Cardio-Oncology: A Novel Platform for Investigation. Room E353C 10:15am - 11:45am CST. #CancerResearchSavesLives #TuftsMedicine
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MCRI Jaffe Lab retweeted
Tufts Medical Center Research@TuftsMCResearch
29 Apr 2025
The talk describes a new mechanism discovered in @IrisJaffeLab showing how drugs that treat certain leukemias also cause heart attacks strokes in cancer survivors. This research sets the stage for new treatments to protect leukemia survivors from CV side effects #AACR25
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Congratulations Alec Stepanian on a fantastic presentation. Alec was one of only 10 MD/PhD students across the country chosen to speak at the ASCI/AAP meeting in Chicago. @TuftsMedSchool @TuftsMedicalCtr @hboucher3
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Congratulations Alec Stepanian on a fantastic presentation. Alec was one of only 10 MD/PhD students across the country chosen to speak at the ASCI/AAP meeting in Chicago. ⁦@TuftsMedSchool⁩ ⁦@TuftsMedicalCtr⁩ ⁦@hboucher3⁩
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MCRI Jaffe Lab retweeted
Tufts School of Medicine@TuftsMedSchool
22 Apr 2025
The definition of bridging the #bench-to-bedside divide: Iris Jaffe is the inaugural director of the Tufts University–Tufts Medicine Research Enterprise #transformative @TuftsUniversity @TuftsMedicine @IrisJaffeLab ow.ly/hVF450VFGcq
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Congratulations Lauren Biwer on receiving the Early Career Investigator in Atherosclerosis Award at Vascular Discovery. ⁦⁦@TuftsMedicine⁩ ⁦@YaleMed⁩
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MCRI Jaffe Lab retweeted
Tufts Medical Center Research@TuftsMCResearch
12 Feb 2025
#TuftsMedicine’s @NavinKapur4 presents at #THT2025 on Safety and Efficacy of the preCARDIA System to Mechanically Reduce Cardiac Preload for Acutely Decompensated Heart Failure. 📍 Ensemble A-B | Level 2 ⏰ 7:55 – 9:12 am #Cardiology @IrisJaffeLab
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Congratulations Alec Stepanian for a fantastic presentation and for winning the Jonathan Epstein Scholar award at the 227th ICC meeting. ⁦@TuftsMedicalCtr⁩ ⁦@TuftsMedSchool⁩ ⁦@TuftsMCResearch⁩
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MCRI Jaffe Lab retweeted
Karen Freund MD@KarenFreundMD
1 Oct 2024
Our amazing #bircwh scholars at the annual meeting @NIH_ORWH @ErikaWernerMD @IrisJaffeLab @TuftsMedSchool @TuftsNutrition
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Congratulations Casey Turner on her F32 grant from the NIH and her mentor Jennifer DuPont. @TuftsMedicalCtr @TuftsMCResearch
Dr. Jennifer DuPont, PhD@DrJenDuP
20 Aug 2024
An exciting day in the lab celebrating @CaseyGTurner1 's F32 award! Thank you to our MCRI colleagues for celebrating with us and to the @NIH for supporting our trainees! @IrisJaffeLab @BlantonLab @karla_cmarqs @amandakmauro @nicolelorrainew @TuftsMCResearch
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Congratulations Nicole Wolter, Tufts MD PhD student for her AHA early career travel award. ⁦@TuftsMedSchool⁩ ⁦@hboucher3⁩
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MCRI Jaffe Lab retweeted
MCRI Jaffe Lab@IrisJaffeLab
16 May 2024
Fantastic talk from Alec Stepanian Tufts MD PhD student at AHA Vascular Discovery Conference in Chicago showing his innovative mechanism for arterial thrombosis in cancer patients treated with Ponatinib. ⁦@TuftsMedicalCtr⁩ ⁦@TuftsMedSchool⁩ ⁦⁦@MTChinMDPhD⁩ ⁦
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Tufts MD PhD student Nicole Wolter gave a spectacular talk at the AHA Vascular Discovery Conference in Chicago. I couldn’t be more proud. ⁦@TuftsMedicalCtr⁩ ⁦@TuftsMedSchool⁩ ⁦@TuftsMCResearch⁩ ⁦@hboucher3⁩ ⁦@MTChinMDPhD⁩
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Fantastic talk by Oncology Fellow Ricky Travers at the AHA Vascular Discovery Conference in Chicago. ⁦@TuftsMedicalCtr⁩ ⁦@TuftsMCResearch⁩ ⁦@hboucher3⁩ ⁦@KarenFreundMD⁩
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Fantastic presentations by post doctoral fellow Jaime Ibarrola and MD PhD student Nick Camarda and AHA Vascular Discovery in Chicago. ⁦@TuftsMedicalCtr⁩ ⁦@TuftsMedSchool⁩ ⁦@TuftsMCResearch⁩ ⁦@hboucher3⁩
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