It’s been great interacting with our readers, reviewers, authors, editors, & others in 2024. As #JNR takes on new leadership, this page will transition to something else. Thanks, @SalahuddinMoh19! Here’s to an ultra productive 2025! 🥂🍾
Parvalbumin interneurons, linked to autism spectrum disorder, could be targeted for therapeutic interventions due to genetic and environmental factors, mutations, and oxidative stress. Read: buff.ly/3NKyBjK#neurosceince#medtwitter#neurotwitter
The study reveals gut vagal sensory neurons and the cNTSNA-to-vlBNST circuit modulate learned passive avoidance behavior in rats, suggesting a dynamic role in memory consolidation and extinction. Read: buff.ly/3Yeh1cY#neurosceince#Medtwitter#neurotwitter
NaV1.7–ChR2, NaV1.8–ChR2, and NaV1.9–ChR2 mice showed nocifensive behavior to blue light exposure, with paw withdrawal and shorter time spent in blue LED rooms compared to wild-type mice. Read: buff.ly/3BREAAV#neuroscience#Medtwitter#Neurotwitter
Treatment-resistant depression is linked to functional dysconnectivity of the thalamus, insula, superior temporal cortex, anterior paracingulate cortex, and cerebellum crus II. Read: buff.ly/4e15Mus#neuroscience#Medtwitter#Neurotwitter
High motor impulsivity in rats is linked to low cortico-striatal function, but chemogenetic restoration can reduce motor impulsivity without affecting risky decision-making. Read: buff.ly/3Y1lzV8#neuroscience#medtwitter#neurotwitter
Recent discoveries reveal altered Stathmin-2 (Stmn2) function in humans with amyotrophic lateral sclerosis and in rodent models, leading to axon degeneration and motor impairment, crucial for neurodegeneration treatment. Read: buff.ly/4eq6WzY#neuroscience#medtwitter
Adverse social experiences in adulthood, like social defeat, promote vulnerability, while maternal separation and social defeat foster resilience, with activity-dependent plasticity crucial for overcoming adversity. Read: buff.ly/3Zm2Rsx#neuroscience#medtwitter
The study demonstrated significant changes in resting-state functional activity and connectivity in the left dorsolateral prefrontal cortex, confirming its effects in both proximal and distant cortical areas. Read: buff.ly/3z8Kwo6#neuroscience#medtwitter#Neurotwitter
IL-4, derived from immune cells, stimulates Ly6C macrophages to express BDNF, leading to a significant decrease in BDNF, IL-4 protein lev, and BDNF /Ly6C cell quantity. Read: buff.ly/47g5Q7N#neuroscience#Medtwitter#Neurotwitter
Resistance exercise training has neuroprotective, antioxidant, & anti-inflammatory properties, preventing inflammatory diseases like memory loss and lipid peroxidation in Wistar rats, thereby increasing protein density. Read: buff.ly/3T07m80#neuroscience#medtwitter
Study highlights schizophrenia's disrupted connectivity between the amygdala and DMDN, emphasizing resting-state functional connectivity in understanding treatment efficacy & symptom improvement. Read: buff.ly/4709vGw#neuroscience#medtwitter#neurotwitter
A study on rat ages revealed that chloride reversal potential (ECl) varies with age and SCN region, with ventral SCN experiencing more hyperpolarization and negative at night. Read: buff.ly/3SJiS7I#neuroscience#medtwitter#neurotwitter
The study investigates the age dynamics of SMI-32-immunopositive neurons in cats' dorsal lateral geniculate nucleus and primary visual cortex, using antibodies to track neuronal maturation and motion processing. Read: buff.ly/3AeHn6q#neuroscience #medtwitter#neurotwitter
The study found ( )-catechin can alleviate neuropathic pain in male rats undergoing CCI surgery by triggering the Nrf2-induced antioxidant system, inhibiting TLR4/NF-κB, and producing ROS. buff.ly/4ftyOVm#neuroscience#medtwitter