A computational biology lab at UCLA
Joined June 2019
- Tweets 101
- Following 1
- Followers 213
- Likes 95
1 Photos and videos
Jason Ernst Lab retweeted
Mar 25
I am a guest editor with Martha Bulyk and Katie Pollard of a Genome Biology special collection on "Prioritizing non-coding variants"
Link for more information: link.springer.com/collection…
Submission deadline: November 25, 2026.
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Learning a pairwise epigenomic and transcription factor binding association score across the human genome academic.oup.com/bioinformat…
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Jason Ernst Lab retweeted
MissenseHMM: state-based annotations for missense variants through joint modeling of pathogenicity scores biorxiv.org/content/10.64898… #biorxiv_genomic
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Jason Ernst Lab retweeted
Jan 30
We are excited to release a single-cell and spatial 3D epigenomic atlas of developing human basal ganglia and inhibitory neurons, part of our BICAN effort in collaboration with @lab_paredes @jernst98 @emukamel @CEpigenomics @bpasaniuc
biorxiv.org/content/10.64898…
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Jason Ernst Lab retweeted
Thanks to @ferhatay and Aly Khan, we’re excited to announce a new chapter for RECOMB-RSG 2026. After years with ISCB/DREAM, we are transitioning to an official RECOMB satellite meeting (May 25 in Thessaloniki). recomb-rsg.github.io
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Jason Ernst Lab retweeted
15 Oct 2025
We like to introduce map3C, developed by Joseph Galasso, that drastically improves the mapping and contact calling performance of snm3C-seq and now enables accurate 3D genome modeling. map3C was developed in collaboration with @jernst98 and Frank Alber biorxiv.org/content/10.1101/…
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Jason Ernst Lab retweeted
📣New from Li et al!
📄Whole genome sequence-based association analysis of African American individuals with bipolar disorder and schizophrenia
👉bit.ly/4lWks1M
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Jason Ernst Lab retweeted
5 Oct 2025
GECSI: Large-scale chromatin state imputation from gene expression biorxiv.org/content/10.1101/… #biorxiv_bioinfo
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Jason Ernst Lab retweeted
4 Jul 2025
Genome-wide identification and analysis of recurring patterns of epigenetic variation across individuals: Communications Biology, Published online: 07 June 2025; doi:10.1038/s42003-025-08179-5Recurring genome-wide patterns of epigenetic mark variation… nature.com/articles/s42003-0…
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9 Jun 2025
A new paper: "Genome-wide identification and analysis of recurring patterns of epigenetic variation across individuals" led by Jennifer Zou and @eamaciejewski is now published.
nature.com/articles/s42003-0…
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5 Jun 2025
A new paper: "Identifying associations of de novo noncoding variants with autism through integration of gene expression, sequence, and sex information" led by Luke Li is now published genomebiology.biomedcentral.…
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Jason Ernst Lab retweeted
24 May 2025
Will comparative biology crack the epigenetic code to longevity? New imputed DNA methylation dataset covers 59 tissues from 348 mammals including long living species such as bowhead whale (211 years), bats, and the naked mole rat. Which tissue holds the key to longevity? Which genes, CpGs, and genomic regions? Cutting-edge imputation applied to data from the Mammalian Methylation Consortium.
Emily Maciejewski, Jason Ernst (2025) CMImpute: cross-species and tissue imputation of species-level DNA methylation samples across mammalian species. Genome Biology. pmc.ncbi.nlm.nih.gov/article…
@JasonErnstLab
@eamaciejewski
#epigenetics #compbio #longevity
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21 May 2025
A new paper "CMImpute: cross-species and tissue imputation of species-level DNA methylation samples across mammalian species" led by @eamaciejewski building on our lab's mammalian methylation array collaboration with @prof_horvath is now published genomebiology.biomedcentral.…
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13 May 2025
A new paper "ChromActivity: integrative epigenomic and functional characterization assay based annotation of regulatory activity across diverse human cell types" led by @tevzilla is now published. genomebiology.biomedcentral.…
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Jason Ernst Lab retweeted
Perspective on recent developments and challenges in regulatory and systems genomics academic.oup.com/bioinformat… is out, amazing to think about this with @JuliaZeitlinger, @ferhatay, @mahonylab, @AMathelier, @AleMedinaRivera, @jernst98!
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Jason Ernst Lab retweeted
11 Feb 2025
Here is a press release by @UCLAHealth that nicely summarizes the key findings from our paper published today @CellCellPress. uclahealth.org/news/release/…
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Jason Ernst Lab retweeted
11 Feb 2025
Happy to share our new paper published today @CellCellPress. Thanks to all our coauthors from @dgsomucla, @UCLASemel, and CHDI.
Distinct mismatch-repair complex genes set neuronal CAG-repeat expansion rate to drive selective pathogenesis in HD mice: Cell cell.com/cell/fulltext/S0092…
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Jason Ernst Lab retweeted
22 Dec 2024
Learning a Pairwise Epigenomic and Transcription Factor Binding Association Score Across the Human Genome biorxiv.org/cgi/content/shor… #biorxiv_bioinfo
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Jason Ernst Lab retweeted
19 Dec 2024
Faculty Position in UCLA’s School of Medicine: Broad search in Biomathematics, Biochemistry, Genetics, Pharmacology, Neurobiology, Physiology, Microbiology, Immunology. We seek exceptional scientists committed to research and mentorship. Apply by Jan 19 recruit.apo.ucla.edu/JPF1006…
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After many zoom meetings, discussions & learning from one another about different ways to look at the same data/problem, our perspective article on regulatory genomics is out. We have a “hallmarks of gene regulation” figure which i am planning to use in my talks. Enjoy reading!
Delighted to have worked on this perspective on the cis-regulatory code with @JuliaZeitlinger, @JasonErnstLab, @ferhatay, @AMathelier, @AleMedinaRivera, @mahonylab, @sinhasaur arxiv.org/abs/2411.04363. We provide an overview of current progress and some challenges to think about.
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