@JasonWBusse profile picture
Jason Busse @JasonWBusse

Professor of Anesthesia; Assoc. Director of the MGD Centre for Medicinal Cannabis Research; Canada Research Chair in Prevention & Management of Chronic Pain

Joined September 2015
  • Tweets 556
  • Following 340
  • Followers 727
30 Photos and videos
While fair criticism is welcome and may provide important opportunities to improve or correct publications, erroneous claims offer an opportunity for correction. Our team recently had such opportunity: painphysicianjournal.com/cur…
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We found moderate to high certainty evidence that beta-blockers and CGRP-targeted therapies probably reduce migraine frequency. Calcium channel blockers and anticonvulsants may also be effective for reducing migraine frequency but are less well tolerated: ebm.bmj.com/content/early/20…

Effectiveness and tolerability of pharmacological prophylaxis for migraine headaches: a systematic...

Objectives Migraine headaches are common and potentially disabling disorders, with several interventions available for prevention and symptom reduction. We explored the comparative effectiveness and...

ebm.bmj.com
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Our review found low certainty evidence that several interventional procedures for chronic spine pain show risk of deep infection, dural puncture, temporary altered level of consciousness and prolonged pain or stiffness: bmjopen.bmj.com/content/16/6…

Harms of selected spinal and paraspinal injections and denervation procedures for chronic non-can...

Objective To summarise the evidence on long-term and infrequent harms following selected spinal and paraspinal injections and denervation procedures for chronic non-cancer spine pain. Design System...

bmjopen.bmj.com
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Our review found high certainty evidence that 5 in every 100 active-duty Canadian Armed Forces members live with PTSD and moderate certainty evidence that 12 in every 100 Canadian veterans probably live with PTSD: militaryhealth.bmj.com/conte…

Prevalence of post-traumatic stress disorder among current and former members of the Canadian Armed...

Objective We synthesised the literature to establish the prevalence of post-traumatic stress disorder (PTSD) among current and former members of the Canadian Armed Forces (CAF). Methods We searched...

militaryhealth.bmj.com
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New review out on migraine prophylaxis. Monoclonal antibodies are promising, but trials require replication. Evidence for botulinum toxin, propranolol, topiramate, and valproate was largely at high risk of bias: acpjournals.org/doi/10.7326/…

Effectiveness and Tolerability of Pharmacologic Prophylaxis for Chronic Migraine: A Systematic...

Background: Migraine headaches are considered chronic when they occur on 15 or more days per month. Newer medications are available for prevention. Purpose: To explore the effectiveness and tolerab...

acpjournals.org
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Can access to chiropractic care reduce use of opioids for chronic spine pain? Observational data suggests yes, RCTs needed to confirm: journals.lww.com/painrpts/fu…

Impact of chiropractic care on opioid use for noncancer... : PAIN Reports

ng adults with noncancer spine pain. We searched for eligible randomized controlled trials (RCTs) and observational studies in MEDLINE, Embase, AMED, CINAHL, Web of Science, and the Index to Chirop...

journals.lww.com
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New Consensus Statement on medical cannabis competencies: jamanetwork.com/journals/jam… Important start to ensuring clinicians are prepared to support patients who use cannabis.

Developing Medical Cannabis Competencies

This consensus statement describes the development of a set of core competencies for educating medical students about medical cannabis, including its clinical utility, risks, legal landscape, and...

jamanetwork.com
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New trial (nature.com/articles/s41591-0…) confirms the findings of our 2021 review (bmj.com/content/374/bmj.n103…) that found non-inhaled cannabis products may provide important pain relief to a minority (10-15%) of people living with chronic back pain. Long term effects remain uncertain.

Full-spectrum extract from Cannabis sativa DKJ127 for chronic low back pain: a phase 3 randomized...

Nature Medicine - A phase 3 trial found that VER-01, a full-spectrum cannabis extract, reduces chronic low back pain, improves physical function and sleep and shows no signs of dependence or...

nature.com
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Jason Busse retweeted
Chronic Pain Network@cpn_rdc
26 Sep 2025
💉💊⚕️Michael G. DeGroote National Pain Centre is looking for participants for a qualitative study exploring experiences on opioid tapering to manage chronic non-cancer pain. Sign-up for this opportunity on Pain Connect today: tinyurl.com/2pmt6x9z
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Jason Busse retweeted
Chronic Pain Centre of Excellence@chronicpainCOE
8 Sep 2025
Canadian Veterans living with chronic pain, your voice matters. 🗣️ Help shape better care & support by completing McMaster University’s survey today. 🔗 rsjh.ca/redcap/surveys/?s=K7… 📩 veteransurvey@mcmaster.ca #VeteransCanada #ChronicPainAwareness #VeteranResearch
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Jason Busse retweeted
McMaster Anesthesia@AnesResMAC
11 Aug 2025
Department of Anesthesia Weekly Announcement - August 11th, 2025 - mailchi.mp/593781fd9f61/depa…
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Jason Busse retweeted
McMaster Anesthesia@MacAnesthesia
3 Jul 2025
Welcome to our Research Spotlight featuring Dr. @JasonWBusse! Learn more about what led him to his current career, and how his research has led to medical and policy developments. Find the interview here: instagram.com/reel/DLpq4casn…

McMaster University Department of Anesthesia (@macanesthesia) • Instagram reel

instagram.com
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🚨Our systematic review found that almost 50% of women and a third of men exaggerate their symptoms when undergoing Independent Medical Evaluations. Exaggeration ≠ malingering. Most attendees presented with chronic pain or mild traumatic brain injury: journals.plos.org/plosone/ar…

Prevalence of symptom exaggeration among North American independent medical evaluation examinees: A...

Background Independent medical evaluations (IMEs) are commonly acquired to provide an assessment of impairment; however, these assessments show poor inter-rater reliability. One potential contributor...

journals.plos.org
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We found moderate certainty evidence that preserving the intercostal brachial nerve during breast cancer surgery probably protects against chronic post-surgical pain: sciencedirect.com/science/ar…
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Our analysis of 906,404 tweets regarding ME/CFS identified frustration with labelling the condition as psychosocial and a desire for identification of physical causation and biomedical treatments.
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We also found enthusiasm for the 2021 NICE guidelines that reversed the prior recommendation in favor of graduated exercise therapy, and claims that revisions were the result of patient advocacy efforts: jmir.org/2025/1/e65087/

Impact of the COVID-19 Pandemic and the 2021 National Institute for Health and Care Excellence...

Background: Myalgic encephalomyelitis (ME), also referred to as chronic fatigue syndrome (CFS), is a complex illness that typically presents with disabling fatigue and cognitive and functional...

jmir.org
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Our review of 488 randomized trial protocols found that less than half reported their outcomes as originally specified in the corresponding trial publication. This suggests substantial risk for reporting bias: pubmed.ncbi.nlm.nih.gov/4034…

Metaresearch on patient-reported outcomes in trial protocols and results publications suggested...

Less than half of RCT protocols with planned PROs reported them as specified in corresponding published results, suggesting outcome reporting bias, and PRO reporting quality was often deficient....

pubmed.ncbi.nlm.nih.gov
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Our survey of total joint arthroplasty patients found that 40% were receptive to opioid-free post-op care, and 50% to reduced opioid use after surgery: cureus.com/articles/323929-p…

Patient Perceptions Towards Reduction or Avoidance of Opioids After Knee and Hip Arthroplasty: A...

Background and objective Opioid analgesics are routinely prescribed to manage pain after total joint arthroplasty (TJA) but are associated with several adverse effects. There is a scarcity of...

cureus.com
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We found that medical cannabis as an alternative to opioids for chronic pain may confer similar, but modest, benefits to patients, and reduce the risk of opioid overdose without substantially increasing costs: liebertpub.com/doi/10.1089/c…

Cost-Effectiveness of Medical Cannabis Versus Opioids for Chronic Noncancer Pain - Haron M. Jeddi,...

Background: Chronic noncancer pain (CNCP) affects one in five adults and is commonly managed with long-term opioid therapy. Concerns regarding rare but catastro...

journals.sagepub.com
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Prior reviews report acupuncture is highly effective for diabetic peripheral neuropathy. We found only low or very low certainty evidence, no improvement in function, and that acupuncture provided less pain relief when compared to sham vs. usual care: link.springer.com/article/10…

Acupuncture for the Management of Chronic Diabetic Peripheral Neuropathy: A Systematic Review and...

Current Pain and Headache Reports - Diabetic peripheral neuropathy (DPN) affects up to half of all patients with diabetes mellitus. Acupuncture is often used to manage chronic pain, but its’...

link.springer.com
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