Joined August 2023
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Modern neuroscientists routinely record the complex, goal-oriented, and time-varying activity of thousands of neurons. Can we find representations of neural activity that 1) are human-interpretable and 2) enable the generation of neural activity for unrecorded behavioral conditions? We present our recent work on Generating Neural Observations Conditioned on Codes with High Information (GNOCCHI) 🥔🍝 !! By leveraging unsupervised, information-based diffusion models, GNOCCHI can discover interpretable latent spaces from neural data and generate high-quality neural activity for specific conditions outside of the set of available neural recordings!
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Modern neuroscientists routinely record the complex, goal-oriented, and time-varying activity of thousands of neurons. Can we find representations of neural activity that 1) are human-interpretable and 2) enable the generation of neural activity for unrecorded behavioral conditions? We present our recent work on Generating Neural Observations Conditioned on Codes with High Information (GNOCCHI) 🥔🍝 !! By leveraging unsupervised, information-based diffusion models, GNOCCHI can discover interpretable latent spaces from neural data and generate high-quality neural activity for specific conditions outside of the set of available neural recordings!
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On biological neural data, GNOCCHI-inferred codes can predict target position for held-out trials better than LFADS, suggesting that the representations learned by GNOCCHI can generalize to unseen conditions better than previous models!
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For more information, including additional comparisons to LFADS, check out the pre-print at the link below! Major thanks to all the co-authors who helped make this happen! @arsedle, @chris_versteeg, @DomenickMifsud, Mattia Rigotti-Thompson and @chethan ! arxiv.org/abs/2407.21195

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Jonathan McCart retweeted
Cosyne Workshop Alert! On Tuesday March 5th, @chethan and I are proud to bring you: Understanding Neural Computation using Task-trained and Data-trained Networks. youtu.be/bJ0stLORdgQ

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Jonathan McCart retweeted
Are you a postbac interested in neural engineering / BCIs? 🧠🤖🗣️ Come join our team!! Work directly with our amazing BCI participants. Great exposure for prospective grad/med school applicants! snel.ai/positions
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Jonathan McCart retweeted
Stop by NeurReps 2023 tomorrow morning to hear about how ODIN can help you accurately infer neural latent dynamics from neural recordings! Hint: combine low-dimensional dynamical models with injective, nonlinear readouts!
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If you are interested in estimating neural dynamics from population recordings, come to our poster Tuesday afternoon to hear more about how injectivity can improve the interpretability of your models! #SfN23 PSTR445.20 / XX40
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Jonathan McCart retweeted
Ever wondered whether the dynamics learned by LFADS-like models could help us understand neural computation? @chethan,@arsedle, @JonathanDMcCart, and I developed ODIN to robustly recover latent dynamical features through the power of injectivity! 📜 1/ arxiv.org/abs/2309.064021/
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