We make stuff up for living || Chromatin || Transcription || Epigenetics
Joined September 2018
- Tweets 107
- Following 33
- Followers 139
- Likes 219
2 Photos and videos
Pinned Tweet
1 Feb 2022
Postdoc positions available in the Jothi Lab at NIH to study transcriptional and epigenetic control of gene expression programs controlling cell fate decisions. Please RT!
training.nih.gov/postdoc_job…
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Jothi Lab retweeted
We're thrilled to share our collaborative work with @Jothi_Lab on the human embryo atlas for human blastoid assessment (biorxiv.org/content/10.1101/…). This much-needed work by @hani_jieun provides insights into popular human blastoid models.
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Jothi Lab retweeted
19 Jun 2023
A fascinating close up of how a bee stinger works
📹 Stated Clearly
x.com/blabla112345/status/16…
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Jothi Lab retweeted
26 Sep 2022
Confused by all the "what is epigenetics" discourse?
Well I have just the thing for you -- presenting the Epigenetics Alignment Chart!
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Jothi Lab retweeted
What role does the bivalent chromatin play in differentiating stem cells? Dr Dhirendra Kumar from @Jothi_Lab will join us next Monday to present his latest research on the regulatory role of bivalency in maintaining epigenetic plasticity. Joins via zoom. No registration required.
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Jothi Lab retweeted
6 Nov 2021
There is a lot of pressure on academics to be extraordinarily successful. Is it worth it?
theatlantic.com/family/archi…
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Jothi Lab retweeted
7 Nov 2021
My Department at Thomas Jefferson Univ is hiring a new Assistant Prof. (ad coming soon) in any area of Molecular Biology and Biochemistry! It’s a great Department full of nice people with a lot of collaboration opportunities. DM if you have any question and please RT!
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Jothi Lab retweeted
5 Nov 2021
The Banaszynski lab is hiring a postdoc! We are a chromatin lab studying histone variant biology in the context of both development and disease. Help me spread the word and message me if you are interested. 1/
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20 Oct 2021
Decoding the function of Bivalent Chromatin in development and cancer. Bivalency does NOT poise genes for rapid activation BUT protects promoters from de novo DNA methylation. Bivalent domains have a function after all!
tinyurl.com/375t57zr
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3 Dec 2020
New insights on the function of bivalent chromatin. Bivalency does NOT poise genes for rapid activation BUT protects reversibly repressed genes from irreversible silencing. ‘Poised’ RNA Pol II incompatible with transcription; H3K4me3 not instructive
disq.us/t/3t9kpqt
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3 Dec 2020
Fun fact 3: Activation of bivalent genes is no more rapid than that of other transcriptionally silent genes, challenging the premise that H3K4me3 is instructive for transcription
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3 Dec 2020
Fun Fact 2: Loss of H3K4me3 at bivalent promoters is strongly associated with aberrant hypermethylation and irreversible silencing in adult human cancers.
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3 Dec 2020
Fun fact 1: H3K4me3 at bivalent gene promoters is a product of the underlying DNA sequence, persists in nearly all cell types irrespective of gene expression, and confers protection from de novo DNA methylation.
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Jothi Lab retweeted
2 Dec 2020
This figure is insane.
The extreme underrepresentation of z-values between -2 and 2 (which is just around the commonly used p-value threshold of 0.05) demonstrates publication bias/p-hacking/etc. Sharp edge near the threshold.
Source:
arxiv.org/abs/2009.09440
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22 Nov 2020
Asymptomatic spread of COVID is not a thing, says study based on Post-lockdown SARS-CoV-2 nucleic acid screening in nearly ten million residents of Wuhan, China disq.us/t/3t05qk0
19 Nov 2020
Postdoc positions available in the Jothi Lab at NIH to study transcriptional and epigenetic control of gene expression. Please RT!
training.nih.gov/postdoc_job…
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Jothi Lab retweeted
12 Nov 2020
Spectacular
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Jothi Lab retweeted
22 Sep 2020
We have a 3-yr benchwork (wet lab) research officer position open. This position is jointly mentored by Prof. Patrick Tam and me. For more details: seek.com.au/job/50568775?typ…
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Jothi Lab retweeted
22 Sep 2020
Integrator brings
PP2A to Paused Pol
For termination
#ChromatinHaiku
cell.com/molecular-cell/full…
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Jothi Lab retweeted
6 Aug 2020
Our contribution to understand the role of the Polycomb-associated factor PHF19 in controlling hematopoietic stem cell state and differentiation advances.sciencemag.org/cont…
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