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Jun Liu Lab @JunLiuLab
Joined June 2018
  • Tweets 235
  • Following 371
  • Followers 1,762
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Jun Liu Lab@JunLiuLab
27 Dec 2022
Postdoctoral Positions @JunLiuLab @Yale #CryoET #CryoEM #postdocs #postdocposition #sciencejobs m.yale.edu/qzr7
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Congratulations to @JunLiuLab @YaleMicroPath researcher @guowangbiao for receiving the poster award at the 11th Annual @Yale Biophysics and Structural Biology Symposium!
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Using in-situ single particle cryo EM, the Liu lab has characterized the asymmetrical flagellar sheath of Treponema denticola biorxiv.org/content/10.64898…
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Structural insights into the assembly and evolution of a complex bacterial flagellar motor nature.com/articles/s41564-0… @YaleMed @YaleMicroPath In collaboration with Beile Gao (CAS), Xiang Gao (Shandong University), Matt Baker (UNSW), and Maria Lara-Tejero (Yale University)
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Jun Liu Lab retweeted
YaleMicroPath@YaleMicroPath
5 Dec 2025
New View of Cholera ‘Tail’ Could Inform Treatment m.yale.edu/dddn @guowangbiao @JunLiuLab @NatureMicrobiol

New View of Cholera ‘Tail’ Could Inform Treatment

Researchers took a detailed image of the cholera bacteria’s flagella, which could explain how they move so quickly and offer new routes for treatment.

medicine.yale.edu
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Jun Liu Lab retweeted
Yale West Campus@YaleWestCampus
2 Dec 2025
Congratulations to the Mougous Lab, recent arrivals at Yale’s Microbial Sciences Institute @YaleMicroPath, on their discovery of “umbrella toxins” cell.com/cell/fulltext/S0092… @CellPressNews @YaleMed
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Jun Liu Lab retweeted
SEVEN@guowangbiao
3 Dec 2025
How does the sheathed flagellar motor rotate while adapting to fluctuations of the outer membrane? What happens after the motor is shed? Here is the answer: x.com/JunLiuLab/status/19962… biorxiv.org/content/10.64898…
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Jun Liu Lab@JunLiuLab
3 Dec 2025
#preprint from @JunLiuLab #postdoc @guowangbiao and @YueJianUSTC @YaleMed #Vibriocholerae #flagellum biorxiv.org/content/10.64898…
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Jun Liu Lab retweeted
Andy Goodman@Goodman_lab
3 Dec 2025
An unexpected mechanism for population heterogeneity in the gut microbiome, led by @YaleMicroPath grad student @annapaigez and Ran Mo. cell.com/cell-host-microbe/f…

A commensal bacterium secretes effector proteins to establish population heterogeneity in the gut

Zagieboylo and colleagues demonstrate that the human commensal Bacteroides thetaiotaomicron secretes two self-targeting proteins that induce heterogeneity within its own population. Differential...

cell.com
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#preprint from @JunLiuLab #postdoc @guowangbiao and @YueJianUSTC @YaleMed #Vibriocholerae #flagellum biorxiv.org/content/10.64898…
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Jun Liu Lab@JunLiuLab
18 Nov 2025
linkedin.com/posts/yale-west…

Yale researchers discover cholera bacterium's swimming mechanism | Yale West Campus posted on the...

Cholera has caused numerous global pandemics, with the WHO estimating as many as 143,000 deaths from the illness each year.   The lab of Jun Liu, Yale Microbial Sciences Institute, has uncovered the...

linkedin.com
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Jun Liu Lab@JunLiuLab
17 Nov 2025
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Jun Liu Lab@JunLiuLab
17 Nov 2025
Congratulations to #postdoc @cryoHuaxinYu @JunLiuLab @YaleMed for insightful findings @ScienceAdvances #cryoEM #cryoET #Lambdaphage Structural basis of bacteriophage Ur-lambda infection initiation science.org/doi/10.1126/scia…
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Jun Liu Lab@JunLiuLab
17 Nov 2025
Congratulations to #postdoc @cryoHuaxinYu @JunLiuLab @YaleMed for insightful findings @ScienceAdvances #cryoEM #cryoET #Lambdaphage Structural basis of bacteriophage Ur-lambda infection initiation science.org/doi/10.1126/scia…

Structural basis of bacteriophage Ur-lambda infection initiation

In situ structures reveal molecular insights into infection initiation of bacteriophage Ur-lambda.

science.org
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Jun Liu Lab@JunLiuLab
31 Oct 2025
Beautiful work using #insitu #cryoEM #SingleParticleAnalysis from @guowangbiao @YaleMicroPath in @NatureMicrobiol nature.com/articles/s41564-0…
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Jun Liu Lab retweeted
Yale West Campus@YaleWestCampus
24 Sep 2025
Now in 3D: Yale scientists catch Legionnaires' disease ‘in the act’. bit.ly/nowin3D @Yale @PNASNews @JunLiuLab @YaleMicroPath @Goodman_lab

Now in 3D: Yale scientists catch Legionnaires' disease ‘in the act’

The Yale labs of Craig Roy and Jun Liu have harnessed the power of cryo-EM to solve a 30-year mystery of how the Legionella bacteria works

westcampus.yale.edu
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Jun Liu Lab@JunLiuLab
23 Sep 2025
Great work from @YueJianUSTC @YaleMicroPath @YaleMed in @PNASNews #Legionella #T4SS pnas.org/doi/10.1073/pnas.25…

In situ structures of the Legionella Dot/Icm T4SS identify the DotA–IcmX complex as the gatekeeper...

The Dot/Icm machine of Legionella pneumophila is among the most versatile type IV secretion systems (T4SSs), capable of translocating more than 330...

pnas.org
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Jun Liu Lab retweeted
Yale West Campus@YaleWestCampus
4 Aug 2025
The Stavroula Hatzios lab has revealed how different gut bacteria feed on a dietary antioxidant found in mushrooms – and a potential target pathway for colorectal cancer therapeutics bit.ly/mushroommolecule
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Jun Liu Lab@JunLiuLab
11 Jul 2025
Happy to share @JunLiuLab @YaleMed #postdoc Samira Heydari’s chapter on #cryoET @ElsevierConnect shop.elsevier.com/books/cryo…

Cryo-electron Tomography

Cryo-Electron Tomography: A Journey from Sample Preparation to Data Mining providing a holistic overview of this rapidly advancing field and equipping

shop.elsevier.com
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Jun Liu Lab@JunLiuLab
30 Jun 2025
Exciting findings from @JunLiuLab #postdoc @YueJianUSTC @YaleMed Architecture and activation of the Legionella Dot/Icm type IVB secretion machine #cryoEM #cryoET #Legionella biorxiv.org/content/10.1101/…

In-situ structures of the Legionella Dot/Icm T4SS identify the DotA-IcmX complex as the gatekeeper...

The Dot/Icm machine in Legionella pneumophila is one of the most versatile type IV secretion systems (T4SSs), with a remarkable capacity to translocate over 330 different effector proteins across the...

biorxiv.org
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Jun Liu Lab@JunLiuLab
21 May 2025
Congratulations to #postdoc Jiaqi Guo @JunLiuLab @YaleMicroPath on her poster prize at the 10th Annual Biophysics and Structural Biology Symposium @YaleChem #cryoET #cryoFIB #cryoEM medicine.yale.edu/profile/ji…

Jiaqi Guo

My research focuses on how nanoscale structures drive bacterial motility and interact with host cells. In Vibrio cholerae, the pathogen that causes cholera, a

medicine.yale.edu
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Jun Liu Lab@JunLiuLab
19 May 2025
Congratulations to our #postdoc Shoichi Tachiyama @JunLiuLab on his paper @mbiojournal journals.asm.org/doi/10.1128… #T6SS #cryoET

Outer membrane tube formation by Francisella novicida involves extensive envelope modifications and...

Francisella tularensis is an intracellular bacterial pathogen that causes the zoonotic disease tularemia. Following uptake by host cells, the bacteria rapidly escape the phagosome and replicate...

journals.asm.org
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Jun Liu Lab retweeted
YaleMicroPath@YaleMicroPath
2 May 2025
medicine.yale.edu/micropath/… #HIV #research #microbiology @YALEBBS @YaleMed

Ya-Chi Ho promoted to Associate Professor with Tenure

Ya-Chi Ho, MD, PhD, has been promoted to Associate Professor with Tenure in the Department of Microbial Pathogenesis at Yale School of Medicine.

medicine.yale.edu
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