@JunLuLab profile picture
Jun Lu @JunLuLab

Jun is a member of Yale Stem Cell Center

Joined April 2019
  • Tweets 8
  • Following 24
  • Followers 97
2 Photos and videos
Jun Lu@JunLuLab
17 Aug 2020
Is it possible to design virus-specific anti-viral therapeutics to prepare for the next viral outbreak? Check out our new manuscript! In Silico Design of siRNAs Targeting Existing and Future Respiratory Viruses with VirusSi biorxiv.org/content/10.1101/…

In Silico Design of siRNAs Targeting Existing and Future Respiratory Viruses with VirusSi

The COVID-19 pandemic has exposed global inadequacies in therapeutic options against both the COVID-19-causing SARS-CoV-2 virus and other newly emerged respiratory viruses. In this study, we present...

biorxiv.org
3
18
Jun Lu@JunLuLab
2 Apr 2020
A great webnar. Looking forward to
1
2
8
Jun Lu retweeted
Gracjan Michlewski@gmichlew
9 Jan 2020
Post-transcriptional Regulation is the Major Driver of microRNA Expression Variation. Post-Transcriptional regulation rules! #microRNA #miRNA #cancer biorxiv.org/content/10.1101/…

Post-transcriptional Regulation is the Major Driver of microRNA Expression Variation

MicroRNA (miRNA) expression patterns are highly variable across human tissues and across cancer specimens. The intuitive assumption is that transcription is the main contributor to mature miRNA...

biorxiv.org
3
3
Jun Lu retweeted
GuoLabatYale@GuoLabatYale
19 Dec 2019
MLL-AF9 initiates transformation from fast-proliferating myeloid progenitors | Nature Communications nature.com/articles/s41467-0…

MLL-AF9 initiates transformation from fast-proliferating myeloid progenitors

Nature Communications - Not all mutated cells become malignant, suggesting additional requirements for transformation. Here, the authors track blood progenitors from normal to malignancy driven by...

nature.com
2
4
22
Jun Lu@JunLuLab
11 Nov 2019
Our manuscript on bioRxiv: microRNA seedless sites attenuate strong-seed-site-mediated target repression biorxiv.org/content/10.1101/…

microRNA seedless sites attenuate strong-seed-site-mediated target repression

MicroRNAs (miRNAs) regulate protein-coding gene expression primarily through cognitive binding sites in the 3’ untranslated regions (3′ UTRs). Seed sites are sequences in messenger RNAs (mRNAs) that...

biorxiv.org
3
4
Jun Lu@JunLuLab
22 May 2019
Welcome Carl Walkley to our stem cell center! Great to see a friend from the opposite side of the globe.
3
9
Jun Lu@JunLuLab
28 Apr 2019
Wonder what happens to the codons of those mt genes, which is different in mt from nuclear genome
Science News
@ScienceNews
26 Apr 2019
One parasite’s energy factories have gone nuclear. The organism’s mitochondria have transferred all of their DNA to the hosts’ nucleus. ow.ly/HkfF30owKIj
1
Jun Lu retweeted
Nature Portfolio
@NaturePortfolio
25 Apr 2019
A research team reports in Nature that several recently developed CRISPR base editors, which create targeted changes in a single DNA base, can induce widespread off-target effects in RNA, extending beyond the targeted DNA. go.nature.com/2Islggz
16
231
450
Load more