From earlier this week: Shaking out the
#macrophage role in
#muscle_repair
This issue's cover features work by Hiroshi Takayanagi & team
@KU_CRI on that a macrophage subset expressing activin A that facilitates muscle regeneration by acting on satellite cells but contributes to heterotopic
#ossification in pathological settings such as fibrodysplasia ossificans progressiva.
The cover image: Injured skeletal muscle sections from mice immunostained to show embryonic myosin heavy chain (magenta), regenerating muscle fibers indicating necrotic fibers (light blue), and nucleu (blue):
doi.org/10.1172/JCI193797
#Osteoimmunology