Zebrafish lab in University of Manchester with interests in stroke, neuroinflammation, genetics and neurological disease

Joined July 2018
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KasherLab retweeted
I'm incredibly excited to share our new paper "Loss of col4a1 in zebrafish recapitulates the cerebrovascular phenotypes associated with monogenic cerebral small vessel disease" from my PhD work with @KasherLab and @BIG_research 🐟🧠sciencedirect.com/science/ar…

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27 May 2025
What a week! Many congratulations @EmzMcM and @Daisy_Flatman very well deserved. It’s been a pleasure working with you both.
A @KasherLab double whammy!! 🐟 BIG congrats to zebrafish enthusiasts Dr Emily McMahon (@EmzMcM) and Dr Daisy Flatman (@Daisy_Flatman) for passing their PhD vivas last week! 🎉 Excited to see where your research takes you next! 🧠🫀
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20 Nov 2024
Two more excellent talks from Manchester by @nima_geemon and Abigail Bennington at #neuroprotection conference!! @BIG_research @GJBrainResearch
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KasherLab retweeted
Brilliant talks from the Manchester group at #neurorepair2024 #neuroprotection @KasherLab @KieronSouth @EmzMcM @victor_tapia_o
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KasherLab retweeted
We're delighted & very proud to see @sccrilly nominated for this Rising Star award🌟Siobhan was a PhD student, post doc, and fellow with @BIG_research at the GJBRC, before moving this year to @uniofgalway to start her own lab with a prestigious MEDTRAIN Marie Curie fellowship
Replying to @WomeninNeuroUK
Congrats to all the nominees for this amazing milestone! 🎉  #WiNUKAwards2024 #WiNUKRisingStar #InspiringLeadership
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10 Oct 2024
Interested in translational stroke research and/or zebrafish disease modelling?? Check out our exciting MRC DTP studentship with @adrianpj1 @stu_art_here in the @BIG_research @DNS_UOM @GJBrainResearch findaphd.com/phds/project/mr…

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KasherLab retweeted
Check out the link below for a exciting PhD opportunity at the University of Manchester with ourselves & @KasherLab and @adrianpj1 findaphd.com/phds/project/mr…

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Research technician position @XimenaSoto40 lab! Apply!
Replying to @XimenaSoto40
Come join us in @MCF_UoM @SBS_Spotlight and help us assess the functional importance of dynamic gene expression underlying spinal cord regeneration. For more information see the link below jobs.manchester.ac.uk/Job/Jo…
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KasherLab retweeted
Our study into the mechanism behind the reduced blood flow in dementia has been short listed for research story of the year! We would appreciate your vote in the link below
As part of this year’s Heart Hero Awards, we invite you to discover three of our most cutting-edge research projects and vote for the one that inspires you the most. Left to right: ❤️ An AI tool predicting the risk of a heart attack - Professor Charalambos Antoniades @UniofOxford 💊 Developing routes to the first drug treatments for vascular dementia - Professor Adam Greenstein @OfficialUoM 🔬 High-tech scans helping to detect heart conditions - Dr George Joy @ucl We'll be diving into each BHF-funded research project in more detail throughout the month. Learn more and vote now for your favourite here: bhf.org.uk/researchstoryvote
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13 May 2024
Great to see our preprint out. Top work @victor_tapia_o
25-hydroxycholesterol dysregulates brain endothelial cell function and exacerbates cerebral haemorrhage biorxiv.org/cgi/content/shor… #bioRxiv
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KasherLab retweeted
I had a great time at the @DCVS_UoM showcase today. I am really chuffed to have been awarded first prize for my talk! 🐟
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KasherLab retweeted
We did it!! 💨🗻🌧️🌈 Team BIG x @NKMTrust completed the 24.5 mile, 5200 ft ascent that makes up the Yorkshire 3 peaks, battling with sidewards hail, snow and 70 mph gusts! Incredibly grateful for all your donations so far - one last push for 10K! justgiving.com/page/brain-in…
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KasherLab retweeted
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KasherLab retweeted
The Brain Inflammation Group is taking on the Yorkshire Three Peaks Challenge on April 15th to raise funds for @NKMTrust, a wonderful charity that supports essential brain haemorrhage research. Please help us reach our target by donating here: justgiving.com/page/brain-in…
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KasherLab retweeted
On 15th April I will be taking on the Yorkshire three peaks challenge with @BIG_research to raise money for @NKMTrust who fund life saving brain haemorrhage research! Donate using the link below to help us support this worthy cause 🧠👩🏻‍🔬🩸 justgiving.com/page/brain-in…
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13 Feb 2024
Fantastic to see this out now in @iScience_CP. Great work @EmzMcM
12 Feb 2024
My first ever research paper is out !! 👩🏼‍🔬🎉 👉👉pubmed.ncbi.nlm.nih.gov/3832… A natural product "brazilin" inhibits the NLRP3 inflammasome pathway, a key driver of numerous inflammatory human diseases including those affecting the brain such as stroke and dementia.
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KasherLab retweeted
I'm excited to see that the preprint of my PhD research, characterising a natural product inhibitor of the NLRP3 inflammasome, is now out in the World! @KasherLab @BIG_research 👇💥 doi: doi.org/10.1101/2023.10.30.5…

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KasherLab retweeted
30 Oct 2023
An exciting PhD opportunity to join my lab studying NLRP3 inflammasome in vascular dementia. This project is in collaboration with @KasherLab Prof. David Brough, and Dr. Ingo Schiessl. Please contact me for details (roychun-laam.ng@manchester.ac.uk) findaphd.com/phds/project/mr…
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