News from the King Lab @UW. Part of @UWproteindesign and @UWBiochemistry. Some assembly required.
Joined June 2018
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74 Photos and videos
May 8
Last week, Grace Hendricks successfully defended her dissertation and earned her PhD!
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King Lab retweeted
Excited to share our new preprint:
“Computational design of membrane fusion proteins”
Huge thanks to all collaborators, co-authors, @KingLabIPD, and everyone at @UWproteindesign who contributed to this work.
Preprint:
biorxiv.org/content/10.64898…
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King Lab retweeted
.@KingLabIPD ski on a beautiful spring day at Crystal! I love my coworkers 💜💛
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King Lab retweeted
A team presents vaccines for H5 clade #influenza based on a stabilized H5 hemagglutinin stem, which improves the breadth and depth of antibody responses and protects against #H5N1 challenge in immunized mice. @KingLabIPD @anniedosey @UWBiochemistry scim.ag/4reeKei
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Mar 5
🚨 new paper alert 🚨
Here we demonstrate increased anti-RBS neutralizing responses elicited by stabilized influenza H5 immunogens:
bit.ly/4u8UxJl
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Jan 3
Happy New Year! We are delighted to share with you our newest @biorxivpreprint, in which we describe the de novo design of protein nanoparticles with structures tailored to specific applications. Long a dream, it is now reality!
biorxiv.org/content/10.64898…
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4 Dec 2025
Yesterday Dane Zambrano successfully defended her thesis on hybrid lipid-protein nanoparticles! Excellent work Dr. Dane!!
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4 Nov 2025
🚨new paper alert🚨
Here, we show how recently developed ML tools can be leveraged to design self-assembling protein nanoparticle immunogens in the absence of experimentally determined structures of the oligomeric building blocks.
Read more @PNASNews: doi.org/10.1073/pnas.2409566…
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15 Oct 2025
🚨 new paper in @ScienceTM 🚨
Here, we describe and evaluate a "best-of-both-worlds" vaccine technology platform that combines the benefits of mRNA vaccines and computationally designed protein nanoparticle immunogens: bit.ly/47s7btG.
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15 Oct 2025
mRNA vaccines 🤝 designed nanoparticle immunogens
15 Oct 2025
This week's issue of #ScienceTranslationalMedicine has arrived!
New mRNA vaccines generate self-assembling nanoparticles to enhance immunity, dual-targeting "decoys" prevent metastasis and potentiate immunotherapy against melanoma in mice, and more. scim.ag/43lkZUm
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8 Oct 2025
Couldn't have asked for a lovelier day to break ground in our new lab downtown!🌞
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22 Aug 2025
Thanks to Aia, Syed, Dixie, and James for joining us this summer as Rosetta Commons Undergraduate Researchers! We loved working with you these past 10 weeks and wish you the best as you head back home!
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22 Aug 2025
Another day, another @biorxivpreprint!
Here, we show how new machine learning tools can be leveraged to design new self-assembling protein nanoparticle immunogens in the absence of experimentally determined structures of the building blocks. biorxiv.org/cgi/content/shor…
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4 Aug 2025
🚨 New paper alert! 🚨
Here we show that stabilized influenza hemagglutinin HPAI H5 immunogens improve the quality of elicited antibody responses. Thank you to @open_phil for funding this work! bit.ly/4lgr0rM
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1 Aug 2025
🚨 new paper alert 🚨
We present a method for designing protein nanoparticles with two unique faces that can bring together distinct biological targets at controlled distances!
This project was led by Dr. Sanela Rankovic is out now in Nature Materials: tinyurl.com/yj8t476d
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1 Aug 2025
You can also learn more in the most recent
@UWproteindesign blog post: ipd.uw.edu/2025/08/creating-…
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1 Aug 2025
We’re looking for early stage investigators (Sr. Postdocs, Instructors, Asst Profs, etc) to join our ReVAMPP Center designing vaccines and antibodies against paramyxoviruses and bunyaviruses! Read more and apply here: tinyurl.com/MLvax-ESI-app
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9 Jul 2025
The IPD is hiring a new Assistant to the Director! This role provides complex administrative support to IPD leadership and is crucial to keeping operations running. Apply today! bit.ly/4kyguvn
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27 Jun 2025
Congrats on graduating Priya! After working in the lab for 3 years on vaccine adjuvants targeting the CD40 signaling pathway in germinal centers, she earned a Distinguished Researcher in Biochemistry award! Now she's off to work on flu vaccines at NIAID’s Vaccine Research Center.
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