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BalintKintsesLab @KintsesLab

Enthusiastic team of genome engineering and phage therapy aficionados

Joined December 2022
  • Tweets 42
  • Following 308
  • Followers 246
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BalintKintsesLab@KintsesLab
27 Sep 2024
📢 Thrilled to announce our latest research in @CellCellPress! We've created a global ‘superbug map’ for a critically antibiotic-resistant bacterium to inform #phagetherapy 🧵1/11 cell.com/cell/fulltext/S0092…
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New preprint: We mapped global receptor-binding protein compatibility across 1,270 Klebsiella and Acinetobacter phages — identifying conserved adapter domains that define host-range modules for programmable phage engineering doi.org/10.64898/2026.02.20.… #phage #AMR #syntheticbiology
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Turns out phages go beyond binding to mucus. Many latch onto epithelial cells, get internalized, and traffic to the ER using Ig-like adhesins encoded by some of the most abundant gut phages. Our new preprint is out: doi.org/10.64898/2026.02.02.… #phages #preprint #microbiome
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Köszönjük a megtisztelő elismerést, és a rengeteg támogatást! #Straub-plakett #HUNREN #SZBK
HUN-REN Hungarian Research Network@hunren_science
21 May 2025
#KintsesBálint kapta a #Straub-plakettet, a #HUNREN Szegedi Biológiai Kutatóközpont elismerését. Gratulálunk 👏 hun-ren.hu/tudomanyos_kishir… #SZBK @BiologicalRese1 @KintsesLab
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Excited for #ESCMIDGlobal kicking off this week—hope to see you in Vienna! 🇦🇹 Our lab is presenting two posters: Sunday: P2395 | Session 05a Monday: P1835 | Session 03g Come say hi and chat phages & resistance!
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Excited to share a new collaboration with the @Csaba_Pal_Lab, out now in @NatureMicrobiol! The study highlights how ESKAPE pathogens adapt to emerging antibiotics:
Csaba Pal Laboratory@Csaba_Pal_Lab
13 Jan 2025
🚨 Excited to share that our new study, “ESKAPE pathogens rapidly develop resistance against antibiotics in development in vitro” is just published in @NatureMicrobiol. For details, see the 🧵below and read the paper here: nature.com/articles/s41564-0…
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After a year of hard work and breakthrough success, we came together for a festive Christmas party. 🧑‍🔬🍕@ApjokGabor even brewed our own beer—fittingly named Scientists' Bloody Sweat! 🍻 Cheers to innovation and teamwork!Happy holidays from all of us at the Kintses Lab! 🎅#LabLife
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Thank you @phagedirectory and @JessicaSacher for this, excited to see our work being shared! Check out the full story in this week's Capsid & Tail! #AMR #PhageTherapy #Acinetobacterbaumanii
Phage Directory@phagedirectory
10 Dec 2024
A team of Hungarian scientists (@KintsesLab & @balazs_papp_lab) created a global ‘superbug map’ for A. baumannii strains, paving the way for scalable phage therapy to combat AMR infections. Check out the feature blog post in this week's Capsid & Tail to learn more!
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Fantastic news! Congratulations @AzeredoLab
Joana Azeredo@azeredo_joana
23 Nov 2024
📢 Historic day for Portugal and phage therapy! 🇵🇹 A framework was approved, allowing magistral preparation of personalized phage products. 🙌 Grateful to Jean-Paul Pirnay, my group @AzeredoLab Portuguese patients, and doctors who signed a petition inspired by the Belgium model.
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BalintKintsesLab retweeted
HUN-REN BRC Genetics@HUNRENBRCgen
6 Nov 2024
The guest speaker of today's Institute of Genetics seminar was Bálint Kintses, head of the Laboratory of Translational Microbiology at the BRC Institute of Biochemistry. His work on bacteriophage cocktail therapy was published in Cell.
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Thrilled to be featured on @NakedScientists, discussing our work recently published in @CellCellPress on guiding phage therapy with genomic surveillance! #AntibioticResistance #PhageTherapy #GenomicSurveillance
The Naked Scientists@NakedScientists
1 Nov 2024
News pod: @dr_michaelmarks from @LSHTM on mpox; Steve Baker from @Cambridge_Uni on antibodies for AMR; @balint_kintses from @BiologicalRese1 on a superbug map; Elizabeth Graham @ucl on Mayans; Michael Ishida on robot fish; and @EdiaCharlotte on dinosaurs. thenakedscientists.com/podca…
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Excited to see our work on guiding phage therapy with genomic surveillance featured in @NatureMicrobiol News & Views! Thanks to @PhageForward and Lorenz Leitner for highlighting our research! #PhageTherapy #GenomicSurveillance #AntibioticResistance @CellCellPress
Nature Microbiology@NatureMicrobiol
28 Oct 2024
News & Views: @PhageForward and Lorenz Leitner discuss the recent @CellCellPress paper from @KintsesLab @balint_kintses Guiding phage therapy with genomic surveillance nature.com/articles/s41564-0…
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BalintKintsesLab retweeted
INCATE@INCATEurope
22 Oct 2024
Did you know that today, October 22nd, is World Phage Day? This day also marks the beginning of World Phage Week (October 22nd-28th), dedicated to raising awareness about the life-saving potential of #bacteriophages. #WorldPhageDay #WorldPhageWeek #PhageTherapy
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Excited to share that our new paper in @CellCellPress, in collaboration with the @balazs_papp_lab, has been featured in GEN!
Genetic Engineering & Biotechnology News@GENbio
17 Oct 2024
First "Superbug Map" May Advance Phage Therapy for Acinetobacter baumannii Scientists have created a global "superbug map," paving the way for scalable #phagetherapy to combat antibiotic-resistant infections in hospitals. hubs.li/Q02TPBcN0
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BalintKintsesLab retweeted
Azeredo Lab@AzeredoLab
13 Oct 2024
Magistral phage preparation according to the Belgium model of phage therapy is being discussed by the Portuguese government. @azeredo_joana and @DPP_Pires were at the parliament to present the concept as a result of a petition initiated by two patients who received phage therapy.
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BalintKintsesLab retweeted
Cell@CellCellPress
29 Sep 2024
Now online! Genomic surveillance as a scalable framework for precision phage therapy against antibiotic-resistant pathogens dlvr.it/TDpzHm

Genomic surveillance as a scalable framework for precision phage therapy against antibiotic-resis...

By mapping the genetic diversity and geographic distribution of carbapenem-resistant Acinetobacter baumannii, bacteriophage cocktails were developed and designed to treat the maximum number of...

cell.com
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🌐 Bridging fields: #Pathogengenomicsurveillance has revolutionized epidemiology and vaccine development, but its potential in phage therapy remains untapped. Our study highlights the need to bring these fields together. 9/10
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🙏 Gratitude: This journey has been incredible. The work was a collaboration between @KintsesLab, @balazs_papp_lab, @Csaba_Pal_Lab from @BiochemBrc, @BiologicalRese1, the National Public Health Centre (Hungary). Huge thanks to our incredible team and international partners! 10/11
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🤝 Shoutout to @chngin_the_wrld! We hope our work advances the wider application of Acinetobacter phage therapy pioneered by the Patterson case. 🙌11/11
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🔄 From personalized to scalable: Traditionally, phage therapy is personalized and time-consuming. Our map identifies locations where patients need the same phages, scaling up phage therapy and allowing clinical trials. 7/10
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🏥 Clinical impact: By enabling hospitals to prepare in advance, we can save lives, reduce the spread of superbugs, and make phage therapy a routine part of healthcare. 8/10
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💡 Key discovery: Despite hundreds of bacterial variants, only a few strains dominate in each region. This means we can prepare region-specific phage treatments that could tackle up to 80% of local infections. 5/10
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⏳ Timing is everything: Superbug variants spread slowly, remaining prevalent for about 6 years in a region, allowing us to prepare region-specific phage treatments in advance. 6/10
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