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LCSOJournalClub @LCSOJournalClub
Joined March 2021
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LCSOJournalClub@LCSOJournalClub
15 Nov 2024
After 167 entries and more than 800 articles highlighted, #LCSOJournalClub is moving to the group Linkedin account: linkedin.com/in/lcso-lab-5b1… Please follow us there if you are interested in the journal club! We will keep this account open for the history of previous highlights.
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167.1 Only 4 this week: First a Pd-catalyzed synthesis of either 1,1- or 1,2- cyclobutanecarboxamides from cyclobutanols reported by Xiao-Feng Wu and co-workers @likat_rostock /Chinese academy of sciences in @NatureComms rdcu.be/dZbCs
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167.3 A propargylic substitution of mesylates with vinyl boronic acids reported by Bo Xu and co-workers from Donghua University in Tetrahedron sciencedirect.com/science/ar…

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167.4 And finally an activation of 2-methylindole with trifluoroacetic acid for Sp3 C-H functionalization reported by Wang, Zhou, Song and co-workers from Shandong Second Medical University in @AdvSynthCatal onlinelibrary.wiley.com/doi/…
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166.0 Let's start this week by a philosophical bonus: "The Chemical Sciences need introverts too" from Bruce C Gibb @NatureChemistry rdcu.be/dYFB7
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166.4 A selective bioconjugation on Arginine using a designed diketone by Gothelf and co-workers from Aarhus University in @BioconjChem pubs.acs.org/doi/10.1021/acs…

A Diketopinic Reagent for the Reversible Bioconjugation to Arginine Residues on Native Antibodies

Arginine is one of the less commonly targeted amino acids in protein bioconjugation, despite its unique reactivity and abundance on the surface of proteins. In this work, a molecule containing...

pubs.acs.org
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166.5 And finally a carbonyl-directed copper-catalyzed 1,-4 aminohydroxylation of dienes reported by Qiu Wang and co-workers @WangLabDuke from Duke University in @ChemCatalysis cell.com/chem-catalysis/full…
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165.1 Best of 2 weeks. First ynamide-tagged oligonucleotides for bioconjugation reported by Watson, Burley and co-workers @watson_group @BurleyResearch from University of St-Andrews/Strathclyde in @BioconjChem pubs.acs.org/doi/10.1021/acs…

Reactivity Profiling for High-Yielding Ynamine-Tagged Oligonucleotide Click Chemistry Bioconjugat...

The Cu-catalyzed azide–alkyne cycloaddition (CuAAC) reaction is a key ligation tool used to prepare bioconjugates. Despite the widespread utility of CuAAC to produce discrete 1,4-triazole products,...

pubs.acs.org
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165.4 A cobalt-catalyzed trans-dialkylation of alkynes reported by Hanmin Huang and co-workers from University of Science and Technology of China in @ChemCatalysis cell.com/chem-catalysis/full…

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165.5 And finally a cobalt-catalyzed hydroalkylation of difluorocyclopropenes reported by Qiang Liu and co-workers from Tsinghua University in @OrgChemFront pubs.rsc.org/en/content/arti…

Cobalt-catalyzed stereoselective synthesis of chiral gem-difluorocyclopropanes with vicinal...

The introduction of fluorine atoms into a cyclopropane ring has been demonstrated to augment both biological activity and bioavailability. Chiral gem-difluorocyclopropanes, especially those incorpo...

pubs.rsc.org
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164.1 only four this week: First the photomediated addition of halotrifluoroacetones to alkenes described by Katayev and co-workers @KatayevL @DCBPunibern in @HelvChimActa onlinelibrary.wiley.com/doi/…
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164.3 A (3 2) annulation of vinyl azides and bicyclobutanes reported by Li Deng and co-workers from Westlake university in JOC @JOC_OL pubs.acs.org/doi/10.1021/acs…

Modular Synthesis of Azidobicyclo[2.1.1]hexanes via (3 2) Annulation of α-Substituted Vinyl...

Here, we present a mild and rapid method to access azidobicyclo[2.1.1]hexanes via formal (3 2) cycloaddition of α-substituted vinyl azides and bicyclo[1.1.0]butanes under Lewis acid catalysis. A...

pubs.acs.org
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164.4 And finally a synthesis of phosphines via the ring-opening of phospharinium ions reported by Dalla, Taillier and co-workers from Normandie University in @NatureComms rdcu.be/dWufi
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