now @buckleylab.bsky.social. We use live confocal imaging and optogenetics to investigate mechanics and cell polarity during epithelial organ morphogenesis
Now that we have polished it a bit, we are excited to share our new preprint with you "Local optogenetic NMYII activation within the zebrafish neural rod results in long range, asymmetric force propagation" biorxiv.org/content/10.1101/…
Now that we have polished it a bit, we are excited to share our new preprint with you "Local optogenetic NMYII activation within the zebrafish neural rod results in long range, asymmetric force propagation" biorxiv.org/content/10.1101/…
This helps to explain how precise morphogenetic patterns can occur across distance in response to relatively small local anisotropies in cellular contractility.
Together, the ability to precisely and reversibly manipulate actomyosin contractility at depth within a physiological in vivo vertebrate system has uncovered rapid, long-range and directional mechanical communication between cells