The Jacks Lab, established in 1992. Koch Institute for Integrative Cancer Research at MIT. Cancer genetics. GEMMs. Tumor immunology. Run by lab members.

Joined June 2021
28 Photos and videos
Pinned Tweet
5 Mar 2025
We've moved!
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17 Jan 2024
We're hiring technicians! Apply below. careers.peopleclick.com/care…

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9 Jan 2024
As the lab gets up and running following the break we'd like to share this picture from the annual holiday party. What a fun time!
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9 Jan 2024
Thanks to Tyler and Laura for hosting!
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30 Nov 2023
The Lab Christmas tree is officially lit! Happy holidays to all :)
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Jacks Lab retweeted
Excited to announce the Yang lab officially opens at @Columbia University. We are interested in developing innovative single cell recording technologies to study tumor evolution and cancer plasticity. We are hiring motivated postdocs & students, please RT dianyanglab.com/
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14 Oct 2023
We were honored to be a part of the annual @lustgartenfdn walk this morning!
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Jacks Lab retweeted
Out today, with @LabJacks, @isidrolauscher, @fran_muyas, we used new mouse models of spontaneous lung and colon cancer to delineate a mechanism for why many patients with DNA mismatch repair deficient (MMRd) tumors may not respond to immunotherapy 🧵1/11 nature.com/articles/s41588-0…
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11 Aug 2023
A heartfelt farewell to our amazing summer students Safya and Michelle! Congratulations on the amazing work and posters!
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14 Jun 2023
Our prime editor mouse is now available to request from The Jackson Laboratory: jax.org/strain/037953 jax.org/strain/037954

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Jacks Lab retweeted
A prime editor mouse to model a broad spectrum of somatic mutations in vivo go.nature.com/3Bk8fz4
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12 May 2023
Excited to share our new publication in @NatureBiotech nature.com/articles/s41587-0… Here, we introduce a genetically engineered mouse model that enables prime editing in vivo! We're excited about the system's potential for rapid and precise modeling of essentially any cancer mutation!

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12 May 2023
Many thanks to our awesome collaborators: @davidrliu, @fjsanchezrivera, and others!
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Jacks Lab retweeted
10 May 2023
Tyler Jacks’ Keynote Lecture: “Genetic engineering meets tumor immunology: Lessons from mouse models of cancer” @LabJacks #eacrImmunoOncology
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Jacks Lab retweeted
Tyler Jacks from @kochinstitute @MIT presenting eloquent vignettes (called tapas while @EACRnews #eacrImmunoOncology in Spain) on genetic engineering approaches in mice that have revealed profound insights into immuno-oncology and novel targets.
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Jacks Lab retweeted
Ludwig @MIT Co-director Tyler Jacks spoke at #AACR2023 about the use of mouse models of cancer—further engineered to express cancer antigens or accumulate mutations in cancer cells—as a tool for nuanced and comprehensive study of anti-tumor immune responses.
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15 Feb 2023
Great to see our very own @KarenKarenoyee featured in @kochinstitute my voices! Thank you Karen for all you do!
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13 Feb 2023
We are currently hiring technicians! Apply if you're interested in 🐭 models of cancer, there are opportunities across cancer types and all of our research areas: careers.peopleclick.com/care…

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19 Jan 2023
Tried and failed to go the the @muddycharlespub and revive lab Muddy Wednesdays (they were closed) 😭, but succeeded at having a great time!
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11 Nov 2022
RT @kochinstitute: Congratulations to Tyler Jacks, recipient of the Ernst W. Bertner Memorial Award! Professor Jacks will be giving his aw…
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