@LabNetz profile picture
Netz Lab @ UNC | Chapel Hill @LabNetz

We love electrochemistry and biophysics. We blend the two to create continuous molecular monitors for health and biomedical research applications.

Joined June 2020
  • Tweets 486
  • Following 352
  • Followers 1,020
141 Photos and videos
New Publication! Can “off-the-shelf” aptamers work in plasma? Erin Demek shows how proteins and fatty acids disrupt aptamer sensors – and how simple sample prep restores buffer-like sensitivity. Read more: nature.com/articles/s44328-0… #Biosensors #Aptamers #AnalyticalChemistry

General approach to achieving electrochemical aptamer-based sensor sensitivity of buffer in blood...

npj Biosensing - General approach to achieving electrochemical aptamer-based sensor sensitivity of buffer in blood plasma

nature.com
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We've adapted our glucometer-based antibody assay to a 96-well plate format, making it more scalable and broadly applicable beyond SARS-CoV-2. 👏 Kudos to Elysse Ornelas-Gatdula & Xinran An for this exciting advance! 🔗pubs.rsc.org/en/content/arti… #biosensors #womeninscience

Adapting antibody–invertase fusion protein immunoassays to multiwell plates for infectious disease...

Traditional enzyme-linked immunosorbent assays (ELISAs) rely on horseradish peroxidase (HRP)-conjugated antibodies to generate a colorimetric response proportional to target antibody concentration....

pubs.rsc.org
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Going from benchtop sensors to in vivo testing is tough. In his final PhD work, John Mack explored using 3D printing to simplify subcutaneous electrode systems. He shared all .stl files to help others get started: iopscience.iop.org/article/1… #InVivo #Electrochemistry #OpenScience
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Excited to share new work with David Jenkins on NHC monolayers for biosensing! Phattananawee Nalaoh & Vincent Clark show aptamer-clicking to NHCs is possible. Still facing capacitive & peroxide issues but stronger gold bonding is a big step forward! pubs.acs.org/doi/full/10.102…
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Many students I talk to feel alone in their stress and uncertainty about academia. But they’re not. Sharing our stories can be healing, for us and for others. In this editorial, I reflect on the challenges and lessons from building my research career: 🔗iopscience.iop.org/article/1…
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Our new lab space at UNC is starting to look ready for transformation! What do you think it should look like? If you have 5 min to kill, share your thoughts with us at the link below: netzlab.unc.edu/2025/07/18/o…
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A new input: When you enter, there is a portal. Lab coats and safety gear are dispensed. Going through the portal alters the mood of all who enter, transforming a tired person into a productive scientist. Copilot's version:
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My daughters think it should look like this:
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Microsoft Copilot thinks it should look like this:
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🔬 New from our lab: H₂O₂ generated during NBE sensor interrogation (with reporter methylene blue) drives oligo hydrolysis. We show mitigation strategies in vivo results with improved stability, no pretreatment or baseline subtraction! 📄 pubs.acs.org/doi/10.1021/acs…

Extending the Operational Lifespan of Nucleic Acid-Based Electrochemical Sensors via Protection...

Nucleic acid-based electrochemical sensors (NBEs) have emerged as a promising approach to continuous molecular monitoring in vivo. NBEs consist of electrically conductive gold surfaces coated with...

pubs.acs.org
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Congrats Dr. John Mack! 🎓 Just defended his PhD in @BCMB_JHMI. I am inspired by his contributions: from diving into biosensor biostats to developing novel additive manufacturing for sensor development. Excited for his next chapter @ DEKA R&D! #PhDDefense #Mentorship #Innovation
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It’s official: I’ve received tenure at UNC Chapel Hill! Grateful, excited, and ready to push the frontiers of science with the amazing Tar Heel community. Let’s lead with creativity, innovation, and inclusive excellence. #Tenure #STEM #AcademicTwitter bot.unc.edu/approved-personn…

Approved Personnel Actions - Board of Trustees

Faculty and Non-Faculty Appointment Personnel Actions Approved by the Board of Trustees on 05/13/2026 Promotions Conferring Tenure Ashley Anderson College of Arts & Sciences Political Science Wubin...

bot.unc.edu
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It was a true pleasure collaborating with the @FUTURUMCareers team to create this open-access academic resource for students around the world. Though my background is in chemistry, our research is highly multidisciplinary. Learn more about our work at: netzlab.unc.edu!

Home - Netz Lab at UNC Chapel Hill

Our Vision Imagine being able to monitor key molecules in your body as you go about your daily life, empowering informed decisions about your diet, fitness, medical treatments, and overall health. At...

netzlab.unc.edu
FUTURUMCareers
@FUTURUMCareers
14 May 2025
In our latest animation, we explore the work of Dr Netz Arroyo from the University of North Carolina Chapel Hill (@UniversityofNo7). Netz is developing a new type of continuous molecular monitor that will be able to track our health in real time: youtu.be/jHlS7rkk2dg
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Happy to be part of the latest Futurum issue: all about inspiring future scientists to dive into STEM! Hope it sparks some curiosity and big dreams. We’re on page 8 if you want to check it out 👉 futurumcareers.com/Issue-31.… #STEM #FutureScientists #FuturumCareers

FUTURUMCareers
@FUTURUMCareers
7 Apr 2025
Issue 31 of Futurum is out now! As Oby Oputa at the University of London Careers Service, enthuses, “there are thousands of jobs out there that you might not know about, and it’s never too early to get researching.” Be inspired and find your passion… #stemeducation #careers #careersadvice #teachingresources futurumcareers.com/Issue-31.…
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After an amazing spring break visit to Hopkins and a celebratory bday cake, we are thrilled that Kian will be our first Chem student from UNC to join the group. We look forward to making your PhD training experiences exciting and rewarding, Kian! tarheels.live/netzlab/2025/0…
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We're always inspired by the stunning journal cover art from our colleagues in the field. This time, we’re thrilled to showcase one of our own! 🎉 📄 Read our paper: pubs.acs.org/doi/10.1021/acs… 🎨 Here’s the cover: tarheels.live/netzlab/2025/0…

Therapeutic Drug Distribution across the Mouse Brain Is Heterogeneous as Revealed by In Vivo,...

Drug discovery for central nervous system (CNS) targets is a high stakes process with estimated success rates below ten percent. Dose scaling, penetration through the blood–brain-barrier (BBB), and...

pubs.acs.org
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💊Whole brain homogenate is often used to measure drug penetration, but the brain isn’t uniform!🧠 In a study led by Dr. Karen Scida we show drug uptake & distribution kinetics vary across brain regions. pubs.acs.org/doi/full/10.102… #DrugDiscovery #Neuroscience #Pharmacokinetics

Therapeutic Drug Distribution across the Mouse Brain Is Heterogeneous as Revealed by In Vivo,...

Drug discovery for central nervous system (CNS) targets is a high stakes process with estimated success rates below ten percent. Dose scaling, penetration through the blood–brain-barrier (BBB), and...

pubs.acs.org
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Bringing aptamer biosensors to the clinic is no small feat. Vincent Clark & team designed an aptamer binding emtricitabine (key in HIV prevention). Partnering with the CDC HIV labs, we show high-throughput screening to monitor treatment adherence. onlinelibrary.wiley.com/doi/…
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DNA nanotechnology-based sensors alert! 🧬 In collaboration with Byoung-jin Jeon and Matteo Guareschi, we introduce the Lily Pad—a modular DNA origami platform for detecting analytes with precision using rational engineering principles:👇😱🤯 pnas.org/doi/epub/10.1073/pn…
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Attending the 47th Senior Technical Meeting of the ACS Puerto Rico Section, for the first time with trainee-at-heart Emma, and enjoying terrific presentations by students. Thanks to @cuncilab for hosting me!
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@uprrp super audience!
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