Recent work from our group:
Role of diffusion and reaction of the constituents in spreading of histone modification marks
biorxiv.org/content/10.1101/…
What is the role of diffusion of enzymes/other constituents in the spreading of histone modifications? We simulated a model with diffusion and reaction of reader/writer enzymes to explain the spreading of histone modifications. biorxiv.org/content/10.1101/… (1/5)
Our work is out in @NatureComms. Read the paper if you want a quantitative description of chromatin polymer or plan to simulate chromatin. We answer some fundamental questions. Details below. @sangramjkadam @KiranKumari_@vinoth46m@DuttaShuvadip@mithunmittir (1/10)
Exciting work from our lab in @PLOSCompBiol on histone modification inheritance, post replication.
With collaboration with Prof.Sibiraj Pillai from the electrical department IIT Bombay. Congratulations @nitkal and @ranjithpa.
Our work, modeling the high fidelity inheritance of histone modifications post replication, using ideas from information theory, is published in PLOS computational biology. journals.plos.org/ploscompbi…@ranjithpa
Interesting work from our lab alumnus @AdityaRanganat4 on RNA-binding protein condensates and emergence of fibrillar structures using coarse-grained simulations.
biorxiv.org/content/10.1101/…
RNA-binding protein condensates exhibit a physical phenomenon called aging which results in a loss of dynamicity. We use coarse-grained simulations to show that droplets can access several structural states with distinct intra-condensate environments.
Congratulations Prof. Rohit Srivastava @rsr004 on winning the prestigious SS Bhatnagar Prize in medical sciences. Proud moment for all of us @BsbeIitb@iitbombay
Delighted to share the preprint of our collaborative work with @Afroze_AC @dnarepairlab at Simon's center @NCBStheory. Chech out the preprint showing the role of SMC protein RecN in the repair process during dsDNA breaks in bacteria.
Our labmate @KiranKumari_ receiving PhD degree. Congratulations Kiran! It is great to see your avatar in convocation robe and receiving the degree! Proud of you! Cheers and best wishes! @BsbeIitb@iitbombay@iitbmonash