Twitter of the Lab of Dr. Patrick Shih at UC Berkeley
Joined May 2019
- Tweets 450
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13 Photos and videos
Our lab's new paper is out!
We introduce ENTRAP-seq, a high-throughput in planta assay for multiplexed profiling of protein-coding libraries. Using ENTRAP-seq and machine learning, we discovered transcriptional regulators from ~1,500 plant viral genomes.
go.nature.com/4pw5cL1
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ShihLab retweeted
25 Nov 2025
Multiplexed profiling of transcriptional regulators in plant cells go.nature.com/4pw5cL1
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ShihLab retweeted
19 Nov 2025
Excited to share our lab’s first publication at UGA!
PhD student Taden Welsh's new perspective highlights how plant bacterial synthetic biology could enhance iron mobilization for food crop fortification.🌱🦠🧬
pubs.acs.org/doi/10.1021/acs…
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ShihLab retweeted
15 Sep 2025
Active learning enables discovery of transcriptional activators across fungal evolutionary space biorxiv.org/content/10.1101/… #biorxiv_genomic
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Functional annotations from model organisms are insufficient for robust evolutionary predictions. Active learning across evolutionary space enables generalizable models to accelerate discovery in understudied branches of life.
Preprint: biorxiv.org/content/10.1101/…
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ShihLab retweeted
26 Aug 2025
Big news from Demirer lab: 4 research papers preprinted! Feedback welcomed:
eCIS for plant protein delivery: tinyurl.com/mrx4d878
R2 for targeted insertion: tinyurl.com/5n73za6h
Transient expression: tinyurl.com/38p2ud6w
Chemotaxis assay: tinyurl.com/3nw9haes
👀⬇️
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ShihLab retweeted
7 Aug 2025
A truly enabling new approach by Tara Lowensohn, @WillCody_12 and @Sattely_lab to probe plant genetics at scale.
Single-gene-per-cell delivery coupled to an effective transcriptional selection system.
Libraries in plants.
biorxiv.org/content/10.1101/…
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Check out our new preprint! We examined sources of variability of transgene expression in N. benthamiana agroinfiltration and ways to minimize it. Graduate student Sophia Tang observed FP expression in >1,800 plants over the course of nearly 3 years! biorxiv.org/content/10.1101/…
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ShihLab retweeted
16 Jun 2025
Causes and consequences of experimental variation in Nicotiana benthamiana transient expression biorxiv.org/content/10.1101/… #biorxiv_plants
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ShihLab retweeted
14 May 2025
Today the Shih Lab (@LabShih) presents ENTRAP-seq, a high-throughput assay for functional screening directly in plant cells.
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We're excited to share another work from our lab this week. We present ENTRAP-seq, the first massively parallel reporter assay to characterize protein-coding libraries in plants. Congrats to Simon, Lucas, and all other co-authors.
biorxiv.org/content/10.1101/…
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ShihLab retweeted
12 May 2025
New OA Article: "Quantitative dissection of Agrobacterium T-DNA expression in single plant cells reveals density-dependent synergy and antagonism" rdcu.be/elJ5z
News & Views: "Cooperation and antagonism in Agrobacterium-mediated transformation" rdcu.be/elJ5F
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Happy to share our new publication out today in @NaturePlants where we quantitatively dissect synergy and antagonism that occurs during Nicotiana benthamiana transient agroinfiltration. Congrats to Simon, Matthew, Mitch and all other co-authors!
nature.com/articles/s41477-0…
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We also very much appreciate the associated News and Views article: nature.com/articles/s41477-0…
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