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Vögeli_Lab @LabVogeli

NMR spectroscopy for the elucidation of conformation and communication networks within and between proteins and nucleic acids. University of Colorado, USA

Joined July 2019
  • Tweets 118
  • Following 272
  • Followers 405
49 Photos and videos
Michael is the 1st master's student to graduate from the lab. He did a really great job presenting his data on Dynein and Pin1 #NMR @CUAnschutz @CU_BMG
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A lot of effort behind this one, and a great team to work with. #Omics #NMR @CUMedicalSchool
Morkos Henen@morkos_henen
Apr 16
Our newly published paper with the @dalessandrolab identifies the #PIMT (PCMT1) V120I variant as crucial for enhancing red blood cell storage and reducing hemolysis, highlighting its potential in improving #RBC preservation. #NMR @LabVogeli onlinelibrary.wiley.com/doi/…
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We are excited to announce the first in-person “A to Z Meeting - Ludwig Conference on Alternative Nucleic Acid Conformations in Health and Disease.” September 28th-October 2nd, Oxford, UK #RNA For registration, visit the website: atozconference2026.my.canva.…
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Vögeli_Lab@LabVogeli
20 Nov 2025
We uncover the first evidence that the long-mysterious Zβ domain of ADAR1 binds G-quads, a surprising twist that reshapes how we think about ADAR targeting—opening new directions for understanding the links between innate immunity and splicing regulation. biorxiv.org/content/10.1101/…

Zα and Zβ domains of ADAR1 and ZBP1 bind to G-quadruplexes with low micromolar affinity

While it is well established that the Zα domains of ADAR1 and ZBP1 proteins bind Z-form-prone nucleic acids (Z-NAs), it has also been shown that the Zα domain of ADAR1 binds DNA G-Quadruplexes (GQ)....

biorxiv.org
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Vögeli_Lab@LabVogeli
22 Oct 2025
A new group photo @CUAnschutz #NMR #RNA #IDPs
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Vögeli_Lab@LabVogeli
13 Oct 2025
Exciting new research
Morkos Henen@morkos_henen
13 Oct 2025
New paper from our lab Cromolyn, an #FDA-approved drug, binds selectively to ADAR1p150—revealing a new pharmacophore to tune #RNA editing & immune signaling in #Cancer. @CUCancerCenter @CU_BMG Collab w/ Rincon & Quentin Vicens labs @qvicens @LabVogeli onlinelibrary.wiley.com/doi/…
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Vögeli_Lab retweeted
Morkos Henen@morkos_henen
13 Oct 2025
New paper from our lab Cromolyn, an #FDA-approved drug, binds selectively to ADAR1p150—revealing a new pharmacophore to tune #RNA editing & immune signaling in #Cancer. @CUCancerCenter @CU_BMG Collab w/ Rincon & Quentin Vicens labs @qvicens @LabVogeli onlinelibrary.wiley.com/doi/…

Cromolyn as a novel pharmacophore of the Zα domain of the RNA‐editing enzyme ADAR1p150

ADAR1p150 is a critical RNA-editing enzyme for maintaining cellular homeostasis through dsRNA binding, protein–protein interactions, and adenosine-to-inosine (A-to-I) editing. Beyond its dsRNA...

onlinelibrary.wiley.com
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Vögeli_Lab@LabVogeli
22 Sep 2025
Intrinsically disordered cytoplasmic tail in netrin receptor DCC binds... #IDP #NMR sciencedirect.com/science/ar…
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Vögeli_Lab@LabVogeli
15 Sep 2025
Celebrating our new paper with @Meg_Filbin @natasiainthelab and @morkos_henen #NMR #RNA
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The finish of Cancer Center CREU program. ⁦@CUCancerCenter⁩ ⁦@CUAnschutz⁩ ⁦@CU_BMG⁩
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Please join us congratulating Dr. Natasia Paukovich, who successfully defended her Ph.D. thesis today. @CUAnschutz @natasiainthelab #NMR #IDP
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Our 1st paper of 2025 #CellPress @STARProtocols Protocol for converting assigned NOESY series peaks into exact distance restraints #NMR #drug_discovery @CU_BMG @CUAnschutz @morkos_henen star-protocols.cell.com/prot…
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Vögeli_Lab@LabVogeli
14 Feb 2025
TENURE-TRACK FACULTY POSITION Department of Biochemistry and Molecular Genetics University of Colorado Anschutz Medical Campus. #EM #Structural @CUAnschutz @CU_BMG
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Vögeli_Lab@LabVogeli
10 Dec 2024
Here is our new graduate Dr. Nichols #NMR @CU_BMG @CUAnschutz
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The new group photo #NMR @CU_BMG @CUAnschutz
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Vögeli_Lab@LabVogeli
14 Sep 2024
A great study
Morkos Henen@morkos_henen
14 Sep 2024
One of the largest study to characterize metabolites in ultramarathon runners. A great effort and amazing contributions from runners. #runrabbitrun @travisnemkov @dalessandrolab @CU_BMG @CUAnschutz
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Vögeli_Lab retweeted
Morkos Henen@morkos_henen
14 Sep 2024
One of the largest study to characterize metabolites in ultramarathon runners. A great effort and amazing contributions from runners. #runrabbitrun @travisnemkov @dalessandrolab @CU_BMG @CUAnschutz
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Our new paper on ZBP1 protein. 1st step to decipher this protein on the molecular level #NMR #RNA link.springer.com/article/10… @jeffrey_krall @morkos_henen

Solution NMR backbone assignment of the N-terminal tandem Zα1-Zα2 domains of Z-DNA binding protein 1

Biomolecular NMR Assignments - The detection of nucleic acids that are present in atypical conformations is a crucial trigger of the innate immune response. Human Z-DNA binding protein 1 (ZBP1) is...

link.springer.com
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Vögeli_Lab@LabVogeli
22 Aug 2024
Spinning in Seoul, South Korea. The #ICMRBS banquet dinner and meeting with the legendary #NMR scientists @CU_BMG @morkos_henen
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Vögeli_Lab@LabVogeli
21 Aug 2024
Spinning in Seoul, South Korea. At Lotte World Tower, 6th tallest building in the world #ICMRBS #NMR @morkos_henen
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