Where science meets society: bite-sized medical news and insights for today’s dynamic physician.
Joined July 2009
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Over-attributing MF anemia to inflammation isn't minor — it's how Luspatercept and ESA candidates get overlooked while JAK inhibitors get the focus.
The 3 misclassifications, with ASH's @AaronGerds : tinyurl.com/4ydva5xb
#MPNsm #HemeOnc
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No gepant had ever been studied prospectively in cluster headaches. Until #AHS2026. Small, open-label, no placebo arm, but a signal worth knowing for a population with thin acute options.
Our breakdown → tinyurl.com/ynrjj64p
#HeadacheMedicine #Neurology #Migraine
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"When do I commit to prevention?" finally has a data-backed answer.
#AHS2026: ROC modeling across 15,000 patients pins the monthly-headache-day threshold where moderate-to-severe disability sets in. tinyurl.com/ynrjj64p
#HeadacheMedicine #Neurology #Migraine
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He asks you to check his testosterone. The visit was never about testosterone.
This Men's Health Month: OSA, cardiometabolic risk, occult depression, sarcopenia — the screens that actually move the needle, and the one that gates whether you can treat.
Full logic on MDLinx: tr.ee/nc2nk5
#MensHealthMonth #Urology #PrimaryCare #MensHealth #Endocrinology
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Hot off the floor at #ASCO26: SV pembrolizumab in treatment-naïve NSCLC — PD-L1 high expressors. The ORR data is turning heads. What's your guess? → Think you know? Prove it. tr.ee/ZprcXF
#LungCancer #Oncology #NSCLC
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Practical implication from RASolute 302: order KRAS status at diagnosis for every mPDAC patient.
Daraxonrasib's pan-RAS mechanism covers G12, G13, and Q61 variants — that's the vast majority of your pancreatic patients in a single agent. 90-second read on what changed at ASCO 2026.
MDLinx oncology brief: tr.ee/Zs9foX
#ASCO2026 #PancreaticCancer #KRASmutation #PrecisionOncology #MDLinx
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A physician alleges One Medical terminated her after she raised patient safety concerns.
The offer: 3 months severance, one NDA. The lawsuit is now testing what clinical governance looks like inside a $3.9B Amazon-owned primary care network.
tr.ee/GXiHhB
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Landmark ctDNA detection at week 12 vs. serial monitoring in early breast cancer: ESMO 2026 showed these identify partially overlapping patient populations — not the same patients.
The clinical implications for adjuvant escalation decisions are different depending on which strategy you're using. tr.ee/T1HT4R
#ctDNA #ESMOBreast2026 #oncology
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FDA rejected MDMA-assisted therapy. Psilocybin is still Schedule I. Ketamine is legal and widely available.
Nearly half of physicians aren't comfortable counseling patients on any of it, even as the questions multiply.
Clinical framework for the conversation you're already having: tr.ee/sjufvS
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Every physician has felt the hierarchy.
Which specialty takes the most professional disrespect from peers, from patients, from the system?
Doctors just put it on the record. The answers are worth reading if you've been on either side of the referral. tr.ee/YWNVO3
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NMN — the anti-aging supplement your pancreatic cancer patients may already be taking, protected tumor cells from oxaliplatin, 5-FU, and gemcitabine in new Cancer Letters data.
Mechanism: NAD fuels cancer cell energy, DNA repair, and apoptosis resistance equally well.
Are you asking about supplement use at consult? tr.ee/ZA2HWN
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Parkinson's diagnosis in high-functioning athletes is delayed an average of 2–3 years after motor symptom onset. Three cases from professional golf that illustrate exactly why. tr.ee/pPs0cB
#parkinsons #Neuro
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AAN 2026: Plasma biomarkers (p-tau217, Aβ42/40) are approaching rule-in/rule-out performance in Alzheimer’s—potentially shifting PET/CSF to second-line.
If validated, this changes triage, referral timing, and diagnostic flow. mdlinx.com/cc/AAN-conference…
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TV medicine isn’t just inaccurate— It’s clinically relevant.
These 5 shows are surprisingly useful tools for patient conversations; if you know how to use them. tr.ee/wax98K
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“Can I boost fat loss while I sleep?”
Patients are coming in with specific strategies — casein protein, vinegar, herbal blends — and expecting clear guidance.
The challenge isn’t the question. It’s answering it quickly, accurately, and without opening a 10-minute nutrition consult.
This piece breaks down:
• Protein timing and overnight metabolism
• Where evidence actually exists
• What to say when the claim outpaces the data
Designed for real clinic flow — not theoretical discussions. tr.ee/7MFEBV
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MDLinx retweeted
Apr 2
I have to say, @MDLinx content (including the daily email that points to it) is incredibly valuable, consumable and timely. Well done! Here's a sample re a blockbuster product that was approved YESTERDAY: mdlinx.com/article/2-oral-gl… #GLP1 #MedTwitter
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Worst states to practice medicine (2026):
Malpractice, pay, workload—some regions are heading in the wrong direction.
Is your state on the list? tr.ee/78irqw
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A familiar format—adapted for clinical thinking.
Medical Connections challenges pattern recognition across specialties:
16 terms, 4 groupings, one daily puzzle.
No prep. No catch-up.
Just a quick way to engage your clinical instincts.
mdlinx.com/games/matchup
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