🚨 Our work exploring polygenic risk scores for Coronary Heart Disease is now out in @JAMA_current and presented at #AHA24 by all-star @SarnoffCardio fellow @sabramowitz_: jamanetwork.com/journals/jam…

Very excited to share our preprint led by @MGLevin @skoyamamd @jakob_woerner & with @damrauer assessing genome-wide pleiotropy of >1,000 clinical traits across ~1.7M individuals with nearly 30K locus-trait associations! medrxiv.org/content/10.1101/… @medrxivpreprint [1/3]

CVI's Highlighted #PapersoftheWeek rdcu.be/egHer

Common-variant and rare-variant genetic architecture of heart failure across the allele-frequency spectrum | ⁦@NatureGenet⁩ nature.com/articles/s41588-0…

Check out this editorial just published in @JAMACardio by our very own💫@PennCardiology fellow Anthony Anguiera & @sabramowitz_ under the mentorship of the one & only @MGLevin! Unfolding the Link Between Transthyretin Stability and Survival jamanetwork.com/journals/jam…

CVI's Highlighted #PapersoftheWeek @MGLevin doi.org/10.1001/jama.2024.23…

New research by @damrauer & @MGLevin suggests that polygenic risk scores may provide conflicting results for detecting heart disease risk. spr.ly/6018scAup

Now out in @JAMA_current: How well do individual risk estimates from different CHD polygenic scores agree? Grateful to work on this with a dream team of mentors and co-authors @damrauer @MGLevin @bpasaniuc @MarylynRitchie @dokyoon_kim @bvoight28 @BoulierKristin @karlkeat