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Cytof Manchester @ManchesterCytof

Tweets relating to #CyTof Helios and Hyperion imaging mass cytometry in University of Manchester's flow cytometry facility. Posted by @ghowell2812 #Cytofpub

Joined July 2016
  • Tweets 2,193
  • Following 364
  • Followers 544
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Cytof Manchester@ManchesterCytof
19 Dec 2017
A Beginner’s Guide to Analyzing and Visualizing Mass Cytometry Data | The Journal of Immunology #cytofpub jimmunol.org/content/200/1/3
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Cytof Manchester retweeted
British Society for Parasitology@BSPparasitology
9 Aug 2023
Another potentially interesting course for parasitologists: the Flow Cytometry Course run by @royalmicro at @UniOfYork - From 4-8 September '23 - Full, Basic, & Advanced courses - All information at bitly.ws/RsDb - Registration open until 𝟯𝟬𝘁𝗵 𝗔𝘂𝗴𝘂𝘀𝘁 '𝟮𝟯
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Dynamics of circulating lymphocytes responding to human experimental enterotoxigenic Escherichia coli infection - Rim - European Journal of Immunology - Wiley Online Library onlinelibrary.wiley.com/doi/… #cytofpub

Dynamics of circulating lymphocytes responding to human experimental enterotoxigenic Escherichia...

In volunteers with diarrhea during experimental infection with enterotoxigenic Escherichia coli, innate immune cell populations responded initially. Then, Th17-like CD4 effector memory cells and...

onlinelibrary.wiley.com
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Congratulations @ProfJudiAllen
Lydia Becker Institute@LydiaBeckerIII
10 May 2023
🎉🎉 Huge congratulations from everyone at the Becker to @ProfJudiAllen who has been elected as a Fellow of the @royalsociety !!
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Frontiers | CD4 T cells expressing CX3CR1, GPR56, with variable CD57 are associated with cardiometabolic diseases in persons with HIV frontiersin.org/articles/10.… #cytofpub

Frontiers | CD4 T cells expressing CX3CR1, GPR56, with variable CD57 are associated with cardiom...

Persons with HIV (PWH) on long-term antiretroviral therapy (ART) have a higher incidence and prevalence of cardiometabolic diseases attributed, in part, due ...

frontiersin.org
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Sleep loss potentiates Th17‐cell pathogenicity and promotes autoimmune uveitis - Liu - 2023 - Clinical and Translational Medicine - Wiley Online Library onlinelibrary.wiley.com/doi/… #cytofpub

Sleep loss potentiates Th17‐cell pathogenicity and promotes autoimmune uveitis

The IL-23–Th17–GM-CSF positive feedback loop drives aggravated autoimmune uveitis after sleep loss. SL increases GM-CSF levels in healthy individuals, patients with SL-induced recurrent uveitis and...

onlinelibrary.wiley.com
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Integrated Proteomics and Single-Cell Mass Cytometry Analysis Dissects the Immune Landscape of Ankylosing Spondylitis | Analytical Chemistry pubs.acs.org/doi/10.1021/acs… #cytofpub

Integrated Proteomics and Single-Cell Mass Cytometry Analysis Dissects the Immune Landscape of...

Mass cytometry is a powerful single-cell technology widely adopted to depict immune cell heterogeneity in different contexts. However, this method is only capable of examining several dozens of...

pubs.acs.org
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McSNAC: A software to approximate first-order signaling networks from mass cytometry data journal.hep.com.cn/qb/EN/10.… #cytofpub

McSNAC: A software to approximate first-order signaling networks from mass cytometry data

Background: Mass cytometry (CyTOF) gives unprecedented opportunity to simultaneously measure up to 40 proteins in single cells, with a theoretical potential to reach 100 proteins. This high-dimensi...

journal.hep.com.cn
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Changes in local tissue microenvironment in response to subcutaneous long-acting delivery of tenofovir alafenamide in rats and non-human primates - ScienceDirect sciencedirect.com/science/ar… #cytofpub
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Early immune pressure initiated by tissue-resident memory T cells sculpts tumor evolution in non-small cell lung cancer - ScienceDirect sciencedirect.com/science/ar… #cytofpub
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The Imaging and Molecular Annotation of Xenografts and Tumours (IMAXT) High Throughput Data and Analysis Infrastructure | Biological Imaging | Cambridge Core cambridge.org/core/journals/… #cytofpub

Imaging and Molecular Annotation of Xenographs and Tumours (IMAXT): High throughput data and...

Imaging and Molecular Annotation of Xenographs and Tumours (IMAXT): High throughput data and analysis infrastructure - Volume 3

cambridge.org
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JCI Insight - Spatial transcriptomic characterization of COVID-19 pneumonitis identifies immune circuits related to tissue injury insight.jci.org/articles/vie… #cytofpub
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Stromal and therapy-induced macrophage proliferation promotes PDAC progression and susceptibility to innate immunotherapy | Journal of Experimental Medicine | Rockefeller University Press rupress.org/jem/article-abst… #cytofpub

Stromal and therapy-induced macrophage proliferation promotes PDAC progression and susceptibility...

Stromal desmoplasia drives local proliferation of TAMs and induces their immunosuppressive ability through altering p21 expression. These changes in p21 in

rupress.org
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T helper 2 cells control monocyte to tissue-resident macrophage differentiation during nematode infection of the pleural cavity: Immunity cell.com/immunity/fulltext/S… #cytofpub

T helper 2 cells control monocyte to tissue-resident macrophage differentiation during nematode...

Current understanding is that, in the steady state, macrophages acquire tissue residency in response to local tissue signals. Finlay et al. show that during nematode infection of the pleural cavity,...

cell.com
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A multiplexed in vivo approach to identify driver genes in small cell lung cancer: Cell Reports cell.com/cell-reports/fullte… #cytofpub

A multiplexed in vivo approach to identify driver genes in small cell lung cancer

Lee et al. report a meta-analysis of published genomic studies to identify candidate drivers of SCLC development in patients. They implement a genetic screening approach in mouse models of SCLC to...

cell.com
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Durable responses to alectinib in murine models of EML4-ALK lung cancer requires adaptive immunity | npj Precision Oncology nature.com/articles/s41698-0… #cytofpub

Durable responses to alectinib in murine models of EML4-ALK lung cancer requires adaptive immunity

npj Precision Oncology - Durable responses to alectinib in murine models of EML4-ALK lung cancer requires adaptive immunity

nature.com
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Implantable niche with local immunosuppression for islet allotransplantation achieves type 1 diabetes reversal in rats | Nature Communications nature.com/articles/s41467-0… #cytofpub

Implantable niche with local immunosuppression for islet allotransplantation achieves type 1...

Nature Communications - Islet transplantation for type 1 diabetes management is hindered by the life-long need for immunosuppressive medications. Here, the authors report an islet encapsulation...

nature.com
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FGL2-targeting T cells exhibit antitumor effects on glioblastoma and recruit tumor-specific brain-resident memory T cells | Nature Communications nature.com/articles/s41467-0… #cytofpub

FGL2-targeting T cells exhibit antitumor effects on glioblastoma and recruit tumor-specific...

Nature Communications - Glioblastoma is an aggressive type of cancer with poor patient prognosis. Here, the authors show that T cells armed with an FGL2-specific scFV can induce antitumour...

nature.com
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Microenvironmental ammonia enhances T cell exhaustion in colorectal cancer: Cell Metabolism cell.com/cell-metabolism/ful… #cytofpub

Microenvironmental ammonia enhances T cell exhaustion in colorectal cancer

Bell et al. identify that ammonia accumulates in colon tumors. The accumulated ammonia reduces tumor immune response by specifically inhibiting T cell function. Removing microenvironmental ammonia...

cell.com
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Targeting the chromatin effector Pygo2 promotes cytotoxic T cell responses and overcomes immunotherapy resistance in prostate cancer | Science Immunology science.org/doi/10.1126/scii… #cytofpub

Targeting the chromatin effector Pygo2 promotes cytotoxic T cell responses and overcomes immunoth...

Pygo2 constrains antitumor T cell immunity and mediates immunotherapy resistance in prostate cancer through the p53/Sp1/Kit/Ido1 axis.

science.org
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ROS Induction Targets Persister Cancer Cells with Low Metabolic Activity in NRAS-Mutated Melanoma | Cancer Research | American Association for Cancer Research aacrjournals.org/cancerres/a… #cytofpub

ROS Induction Targets Persister Cancer Cells with Low Metabolic Activity in NRAS-Mutated Melanoma

Metabolic reprogramming in drug-resistant NRAS-mutated melanoma cells confers sensitivity to ROS induction, which suppresses tumor growth and metastasis in combination with MAPK pathway inhibitors.

aacrjournals.org
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