We study the fascinating non-lethal biology of caspase/metacaspase proteases ☠️. We are also interested in the molecular cues that manage cardiac remodeling🫀

Joined March 2023
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Lynn Megeney retweeted
Lung cancer patients who received an mRNA COVID-19 vaccine within a few months of immunotherapy lived nearly twice as long as unvaccinated patients. sciencenews.org/article/canc…
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Lynn Megeney retweeted
Book signing with Dr Tony Sanfilippo, and his amazing wife Michelle. Tony is the author of “The doctors we need” ⁦@QueensuDOM⁩ ⁦@KingstonHSC⁩ ⁦@queensutime⁩ -a great read on how Canada can solve its doctor shortage problem-a must read!
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Lynn Megeney retweeted
Interesting work from @Rudnicki_Lab in @NatureComms : Intrinsic dysfunction in muscle stem cells lacking dystrophin begins during secondary myogenesis. tinyurl.com/4byakujj

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Lynn Megeney retweeted
Excited to share our paper with Ghayda Mirzaa describing the novel SMARCA1-related NDD. Out today in Nature Communications. rdcu.be/ePaDp

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Lynn Megeney retweeted
We’re proud to celebrate @CincyKidsHeart's Jeff Molkentin, PhD, for receiving @UCincyMedicine's 2025 Daniel Drake Medal—college's highest honor! His groundbreaking work in cardiovascular biology continues to advance science & inspire next-gen researchers: scienceblog.cincinnatichildr…
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Lynn Megeney retweeted
Celebrating an amazing trip up Mount Kilimanjaro with daughter Elizabeth, supported by team Ultimate Kilimanjaro ⁦@UltimateKili@QueensuDOM⁩ ⁦@queensutime⁩ ⁦@KingstonHSC⁩ -19341 feet of challenging, hypoxic beauty. One of the hardest things I’ve ever done!
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one of the most interesting papers on muscle biology in decades....a challenge to the satellite cell hypothesis!!!! Muscle growth by sarcomere divisions | Science Advances science.org/doi/10.1126/scia…
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Lynn Megeney retweeted
New @NatureMedicine paper: AAV mini-dystrophin gene therapy for Duchenne muscular dystrophy: a phase 1b trial. #DMD tinyurl.com/bdhwrkka

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Lynn Megeney retweeted
Interesting new #JACC paper: Long-Term Dystrophin Replacement Therapy in Duchenne Muscular Dystrophy Causes Cardiac Inflammation. tinyurl.com/2t5rv79t
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very cool paper from Assaf Vardi's group on metacaspase function in diatoms. Metacaspases mediate thermotolerance of diatoms following marine heat waves | bioRxiv biorxiv.org/content/10.1101/…
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Lynn Megeney retweeted
Happy to share that our single-cell analysis of muscle stem cells in two DMD models is now published in Cell Death & Disease. We hope this resource benefits researchers in neuromuscular disease and helps to support the development of stem cell targeted therapies for DMD.
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Lynn Megeney retweeted
Huge wall cloud over East Ottawa right now! #onstorm cannot discern rotation
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Lynn Megeney retweeted
Happy to share our new paper demonstrating optimization of base editing to correct the lethal ACTA2 R179H mutation in human smooth muscle cells in vitro and humanized mice, thereby rescuing multisystemic smooth muscle dysfunction syndrome. ahajournals.org/doi/abs/10.1…
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Lynn Megeney retweeted
My name is Tim and I am Nova Scotian 🇨🇦
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Great career perspective in Nature Metabolism from Dr Ben Weaver rdcu.be/ejc9u.
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Lynn Megeney retweeted
It was a lot of fun today getting to talk with the students about life and career challenges! Thanks Arnaldo and Leah for hosting this! x.com/ADiaz_PhD/status/19002…

We cordially invite our community to our upcoming STORIES event on April 8. Join us as we welcome Dr. Benjamin Weaver, who will share his inspiring journey in science. Check out the flyer for details.
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