We study the fascinating non-lethal biology of caspase/metacaspase proteases ☠️. We are also interested in the molecular cues that manage cardiac remodeling🫀
Lung cancer patients who received an mRNA COVID-19 vaccine within a few months of immunotherapy lived nearly twice as long as unvaccinated patients. sciencenews.org/article/canc…
Book signing with Dr Tony Sanfilippo, and his amazing wife Michelle. Tony is the author of “The doctors we need” @QueensuDOM @KingstonHSC @queensutime -a great read on how Canada can solve its doctor shortage problem-a must read!
We’re proud to celebrate @CincyKidsHeart's Jeff Molkentin, PhD, for receiving @UCincyMedicine's 2025 Daniel Drake Medal—college's highest honor! His groundbreaking work in cardiovascular biology continues to advance science & inspire next-gen researchers: scienceblog.cincinnatichildr…
Celebrating an amazing trip up Mount Kilimanjaro with daughter Elizabeth, supported by team Ultimate Kilimanjaro @UltimateKili @QueensuDOM @queensutime @KingstonHSC -19341 feet of challenging, hypoxic beauty. One of the hardest things I’ve ever done!
New @NatureComms paper: Large-scale serum protein biomarkers discovery associated with function and clinical milestones in Duchenne muscular dystrophy. #DMDtinyurl.com/34nufjed
Congrats to @LorsonLab and colleagues for their new @hmg_journal paper: Novel neurofilament light (Nefl) E397K mouse models of Charcot–Marie-tooth type 2E (CMT2E) present early and chronic axonal neuropathy. tinyurl.com/y9x94c8z
one of the most interesting papers on muscle biology in decades....a challenge to the satellite cell hypothesis!!!!
Muscle growth by sarcomere divisions | Science Advances science.org/doi/10.1126/scia…
very cool paper from Assaf Vardi's group on metacaspase function in diatoms. Metacaspases mediate thermotolerance of diatoms following marine heat waves | bioRxiv biorxiv.org/content/10.1101/…
Happy to share that our single-cell analysis of muscle stem cells in two DMD models is now published in Cell Death & Disease. We hope this resource benefits researchers in neuromuscular disease and helps to support the development of stem cell targeted therapies for DMD.
Happy to share our new paper demonstrating optimization of base editing to correct the lethal ACTA2 R179H mutation in human smooth muscle cells in vitro and humanized mice, thereby rescuing multisystemic smooth muscle dysfunction syndrome. ahajournals.org/doi/abs/10.1…
It was a lot of fun today getting to talk with the students about life and career challenges! Thanks Arnaldo and Leah for hosting this!
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We cordially invite our community to our upcoming STORIES event on April 8. Join us as we welcome Dr. Benjamin Weaver, who will share his inspiring journey in science. Check out the flyer for details.