@Menendez_Lab profile picture
Menendez Lab @Menendez_Lab

Great group of people working on developmental cancer, stem cell biology and immunotherapy group at @CarrerasIJC pursuing to cure pediatric leukemia.

Joined April 2020
  • Tweets 973
  • Following 263
  • Followers 1,295
153 Photos and videos
Josep Maria - you are a genious and so generous to others that you deserve this and more. An special person, scientist, husband, father, mentoe and friend of many . Congrats from all our Lab
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Do not miss this opportunity
Josep Carreras Leukaemia Research Institute (IJC)
@CarrerasIJC
Apr 27
🔬 We’re hiring 3 Group Leaders in Paediatric Haematologic Malignancies 🤝 @CarrerasIJC & @IRSJD_info are joining forces to launch a new translational research hub focused on paediatric blood cancers. 📝 Apply now to drive real change for young patients: careers.carrerasresearch.org… @SJDbarcelona_es @fcarreras
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Led by @onechaintx !!!!
ISEH@ISEHSociety
Apr 13
What does a systematic approach to CAR humanization actually look like? This study from Dr. Díaz and @Menendez_Lab explores a robust pipeline for next-generation CAR-T design with translational relevance. Read now➡️ exphem.org/article/S0301-472…
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FUNDACIÓN LAIR – Profesor Durantez Award for Best Scientific Article 2025 for “Engineered T cells secreting anti-BCMA T cell engagers control multiple myeloma and promote immune memory in vivo” goes to Laura Díez Alonso, PhD and Aïda Falgàs Comamala 🏆✨congrats !!!!!
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Closing soon! Please consider joining ISEH in Frankfurt ! Top notch science in experimental hematology !!!
ISEH@ISEHSociety
Apr 11
Abstract submissions close 17 April. Don’t miss your chance to present at #ISEH2026! Share your science with the global ISEH community. 🔗 iseh.org/Annual-Meeting/Abst…
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We present a model of hyperdiploidy, a common form of aneuploidy in childhood B-ALL, in fetal HSPC. Very grateful to our amazing team and collaborators and proud of Namitha Thampi & Oscar Molina’s lab at UB. cell.com/cell-reports/fullte…

Hyperdiploidy impairs fetal hematopoietic progenitor fitness and differentiation enabling persist...

Thampi et al. model prenatal hyperdiploidy in human fetal hematopoietic stem/progenitor cells and show that aneuploidy impairs fitness and delays differentiation. Although hyperdiploid cells are...

cell.com
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Our lab is proud to contribute to Experimental Hematology, the journal of the @ISEHSociety together with our colleagues at @onechaintx on prospective humanization of a Chimeric Antigen Receptor. Heppy reading! Narcis Fernandez et al! pubmed.ncbi.nlm.nih.gov/4188…

A roadmap for systematic humanization of a chimeric antigen receptor: preclinical validation of a...

The humanization of chimeric antigen receptor (CAR) T-cell constructs is essential for reducing immunogenicity while preserving optimal antigen-binding affinity. However, this process poses signifi...

pubmed.ncbi.nlm.nih.gov
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What a privilege to have hosted today Prof Toshio Suda - a giant HSC scientist who pionered research on trancriptional, metabolic and aging features of HSC. His career covers outstanding periods in Japan, Singapore and now in Tianjin (China). Huge mentorship track record!!
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Menendez Lab retweeted
Fundación Fero@FundacionFero
Feb 12
FERO sumó fuerzas con @FundAladina para potenciar la investigación en cáncer infantil. Hoy, ver cómo avanza el proyecto del Dr. Pablo Menéndez (@Menendez_Lab) desde el @CarrerasIJC nos confirma que vamos por el buen camino. ¡Dale al play para ver al equipo en acción!
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Menendez Lab retweeted
Fundación ”la Caixa”
@FundlaCaixa
22 Dec 2025
Detrás de cada avance hay alguien que cree que puede ocurrir. Personas que dedican su vida a acompañar a los demás, a que la brecha se reduzca, y que hacen que lo imposible sólo sea un poco más difícil que las cosas difíciles. Desde la Fundación ”la Caixa” agradecemos a todas las personas que nos ayudan a seguir avanzando hacia un futuro mejor a través de proyectos sociales, investigación y educación al servicio de la sociedad. Porque cuando muchas personas creen y actúan unidas, las utopías se hacen posibles Creer para transformar. Descubre más en fundacionlacaixa.org/es/utop… #FundaciónlaCaixa #DelLadoDeLosQueLoHacenPosible #CreerParaTransformar @hospitaldelmar, @IBECBarcelona, @AbleHumanMotion
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It has been an immense pleasure to celebrate de Namitha Tampi’s PhD dissertation supervised by @oscar_molina @CarrerasIJC @UniBarcelona on aneuploidy contribution to fetal liver origin of pediatric leukemogenesis. All the best Nami from the entire team
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So proud of Aida Falgàs @aidafc8 from @CarrerasIJC and Javi Arroyo @jarroyo8 from @CNIOStopCancer for being awarded tha best paper from the @jitcancer @sitcancer on next generation CART!
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Menendez Lab retweeted
One Chain Immunotherapeutics@onechaintx
27 Oct 2025
Great news 🎉 OneChain will lead a €3M consortium with @VHIO to develop a dual #CART therapy against #glioblastoma, one of the most aggressive brain cancers. The goal: complete preclinical development and move closer to clinical studies!
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What a great day at ReALLnet get together! Thanks to the Fundacion Uno entre Cienmil foe hosting us. Thanks Pablo Velasco for leading us
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Menendez Lab retweeted
Mick Milsom@MilsomMick
30 Sep 2025
Surprising finding that standard chemo treatment induces resistance to menin inhibitors in AML. Published in @ISEHSociety journal Exp. Hem: exphem.org/article/S0301-472…

Upfront menin-inhibitor resistance in multiply pretreated leukemias

Inhibitors of the menin-KMT2A interaction are promising agents for the treatment of KMT2A-rearranged leukemias. We evaluated menin inhibition in patient-derived xenografts of KMT2A-rearranged...

exphem.org
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We are hiring a Molecular/Biochemist scientist for a unique journey in advancing research and therapeutics in pediatric leukemia. Vision shared by Barcelona Children's Hospital Sant Joan de Déu (@SJDbarcelona_es) and Josep Carreras Leukaemia Research Institute (@CarrerasIJC ).
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Come and join us!
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Wow!!!! Our best friends ever 😍
Toribio Lab@ToribioLab
1 Sep 2025
We are so happy to share that our latest paper is finally out in @NatImmunol! 🤩 There’s a lot of work and passion behind this discovery of the preTCR as a novel #immunotherapy target for T-cell acute lymphoblastic #leukemia (T-ALL). 🔬🩸 nature.com/articles/s41590-0… @Nature
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It has been an immense pleasure and growth opportunity for our lab to learn from @MaribelParraLAB on HDAC inhibition in infant 4;11 proB ALL! Thanks team and congrats!!
Maribel Parra LAB@MaribelParraLAB
29 Jul 2025
Replying to @MaribelParraLAB
🙏Of course, we want to thank all our collaborators for their engagement and continuous suport to the project @CarrerasIJC @Menendez_Lab @clarabueno_74 🧡Also thanks to agencies who have funded the project in the last years @AgEInves @SaludISCIII @fcarreras @ContraCancerEs
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The photo fails to capture real credit. Give credit where credit is due! This work has been possible thanks to those who led it: Nestor Tirado, @k_fidyt, many members of @Menendez_Lab and @onechaintx and @ToribioLab and many many other colleagues nationwide. Thanks to all!
Josep Carreras Leukaemia Research Institute (IJC)
@CarrerasIJC
7 Jul 2025
🧬 New research from @Menendez_Lab presents a novel CAR-T cells therapy designed to target 2⃣ specific markers of T-ALL: the CD1a and CCR9 proteins. Preclinical results show high efficacy and safety in the lab, paving the way for clinical development in the short term. 🔗 carrerasresearch.org/en/news… 🤝 @IISAragon, @onechaintx 🚀@contracancerES, @contracancerINV, @contracancerBCN
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