Cofounder of @dittobio, @ycombinator (W26) | prev: @berkeleyMCB @hscrb
Joined January 2012
- Tweets 1,337
- Following 463
- Followers 1,502
- Likes 8,255
236 Photos and videos
Pinned Tweet
Feb 7
Some news: excited to share that I'm building @dittobio with @AdairLBorges and @emilycpierce as part of the @ycombinator W26 batch!
We're discovering drugs for autoimmune disease by harnessing parasite biology.
Shout out @agupta for betting on us. š below:
7
3
23
3,142
Weāre launching @trybaseframe to take you from AI fatigued to AI native.
You already have the AI tools. What you don't have is the time to figure out what to actually do with them, which features are useful to you, and how to use them.
BaseFrame does that for you. Its desktop app finds the repetitive work eating your week that you could automate today with the AI tools you already have.
Download the app and start unlocking hours today. Link below:
44
31
126
16,984
May 21
If youāve been looking for an Acquired equivalent for biotech, it has arrived and you too can listen below
May 14
Keytruda transformed cancer care and made Merck more money than any drug in history. It was also discovered by accident, and nearly out-licensed in 2010 for pocket change.
New Approved exclusive interviews with the inventors and the Merck CMO who ran development:
2
288
Dennis Sun retweeted
Apr 1
The genomics revolution told us which genes cause disease.
What if small molecules could target the genetic message? CRISPR-level precision, in a pill.
Endura Insights #1: why the genomics revolution is only half finished.
enduratx.com/blog/the-genomiā¦
1
4
10
1,557
Mar 19
Thrilled to be building with Pioneer!
Mar 18
š§¬ @dittobio is utilizing parasite strategies for developing breakthrough drugs for autoimmune disease. Why parasites? They've been running experiments on humans for millions of years being able to control the human immune system. Ditto is building an AI platform to identify drug-like proteins from these types of organisms which they then engineer into safe, effective therapeutics.
š¦ šŖ² šŖ± They are just getting started and have already analyzed over a million proteins across primate-infecting viruses, ticks, and parasitic worms. Initial discovery is looking promising!
@pioneer_fund is proud to back these three PhD scientists! Congratulations @AdairLBorges, @Mezarque, and @emilycpierce. Excited to partner with you!
6
251
Mar 5
Founder multitasking:
- listening to a talk on lipid nanoparticle-mediated immune toleranceā¦
- while stress-buying domain names and emailing cloud providers to kill a spoofed website.
At @dittobio we copy natureās playbook to treat disease. šÆ
Today, someone tried copying us.
1
2
3
414
Mar 5
shout out @posthog for helping us notice the spoofer and @GoDaddy @AWSstartups @googlecloud for helping us take them down!
1
3
122
Mar 4
Itās been an incredible 10 months of science at @dittobio, and Iām excited to share some of our progress in our first blog post.
Today, we're sharing our analysis mapping parasite proteins and human diseases they could treat.
dittobio.com/blog/2025-03-02ā¦
1
2
9
321
Mar 4
We highlight how viruses can teach us to find drug targets and even design therapeutic molecules.
For example, viruses were the first to invent drugs like Enbrel (etanercept). (green: TNF; orange: etanercept; blue: a viral protein)
Reach out if you want to learn more!
1
66
Dennis Sun retweeted
Mar 4
Finally got around to writing up some of our progress at @dittobio !
Check out our inaugural blog post to learn how my favorite parasites (aka viruses š) can improve target selection and discover blockbuster drug mechanisms for autoimmune disease:
dittobio.com/blog/2025-03-02ā¦
2
8
512
Mar 3
My @ycombinator puffer is finally fulfilling its true purpose: keeping me warm in the dead of winter.
Iām in Boston this week for the Antigen-Specific Immune Tolerance Summit (as-immunetolerance.com/)!
1
2
103
Mar 3
Iām representing our team at @dittobio ā we copy natureās playbook to build novel therapeutics for autoimmune diseases.
If youāre in Boston and want to meet up, please reach out! Iām excited to talk about platforms, partnerships, and next-gen therapies for autoimmune disease.
57
Feb 27
My top 2 themes from this year's @Biocom Global Partnering & Investor Conference #BiocomGPIC:
1. AI's impact in drug discovery development
2. China <> US competition & collaboration
Every panel conversation kept returning to these two areas. More in thread:
1/n
1
2
5
191
Feb 27
China (cont'd):
- for US companies to stay competitive, capital efficiency is king
- revisions to the regulatory landscape around starting clinical trials (e.g. centralized systems like in AUS/NZ) improved speed to human evidence could level the playing field
4/n
1
37
Feb 27
This was my first time attending. Incredible to hear from luminaries in the field and meet many amazing people working hard to bring new therapies to patients in need.
Thanks to everyone who reached out for a convo / met up!
Follow our work at @dittobio for more :)
43
Feb 24
Excited to be back home in sunny San Diego for @Biocom's Global Partnering & Investor Conference this week. hashtag #BiocomGPIC
Iām here representing our team at @dittobio, where weāre copying natureās playbook to build next-gen protein therapeutics for autoimmune disease.
1
1
5
176
Feb 24
Looking forward to great conversations around platform biotech, partnerships, and new collaborations. If youāre attending, please reach out! Would love to grab coffee and catch up.
1
58
Feb 22
Vapid, grifting, rage bait-driven startups do a disservice to the broader ecosystem b/c the public ( media class) over-indexes on stories like these.
Most founders I know are good, kind, serious people trying to solve real problems. A shame the grifters get outsized attention
Feb 20
āUntil we build an all-powerful but distant God, the agency problem remains. AIs are not capable of directing themselves; most people arenāt either.ā
Sam Kriss reports from San Francisco on the next generation of AI technologists.
harpers.org/archive/2026/03/ā¦
1
1
228