Official account of Microbial Biotechnology journal Original research reporting significant advances in microbial applications @microbiotech.bsky.social
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Kato et al (doi.org/10.1111/1751-7915.70…) engineering bacterial P450 into an H₂O₂-driven biocatalyst boosting activity 28-fold & enabled efficient synthesis of valuable compounds, including indigo dye. A simple, powerful strategy to expand sustainable enzyme-driven chemistry.
Machine learning meets microbiome science: optimized amino acid formulations for Bifidobacterium longum reduced nutrient inputs by up to 77% while maintaining growth. Kaneco et al reveal key amino acids shaping fitness and enables streamlined media design. doi.org/10.1111/1751-7915.70…
Science conversations are evolving. By analysing interactions on X and BlueSky, Bernal et al highlight the microbiology and biotechnology topics our community cares about most: from precision medicine to synthetic biology and sustainability. doi.org/10.1111/1751-7915.70…
Park et al present ways for fighting antibiotic resistance by targeting bacterial persisters. bymBDZ accelerates persister regrowth & increases antibiotic susceptibility in E. coli, boosting killing during early recovery. doi.org/10.1111/1751-7915.70…
A greener future for bioplastics: near-solvent-free recovery of microbial PHAs directly from wet biomass using insect-derived enzymes. High polymer recovery & material quality, and up to 7× lower carbon footprint without drying or toxic solvents. doi.org/10.1111/1751-7915.70…
Adapting Bacteria for Better Bioremediation. Evolving Dehalobacter on mixed substrates boosts 1,1-DCA dechlorination. Key mutations in TmrA enhance binding to xenobiotic pollutants, a new path to engineer more efficient cleanup microbes. Read Ren et al doi.org/10.1111/1751-7915.70…
Engineering Better Fucosylation with Enzyme Design. MBT ( doi.org/10.1111/1751-7915.70…) presents a study led by Patricie Vodičková, that boosts transfucosylation >20× via a single mutation (S237V), enabling precise synthesis of fucosyllactose derivatives for biosensors & diagnostics.
Prototheca, rare pathogenic microalgae, are widespread in wastewater (78% samples). Treatment cuts levels by up to 99.9%, yet detectable cells remain, highlighting WWTPs as potential release routes and the need for routine monitoring safety guidelines. doi.org/10.1111/1751-7915.70…
Healthcare systems are failing on access, equity, and resilience. Timmis et al propose a bold reset: patient-driven digital care, microbial tech innovation, and a shift to prevention, reframing healthcare as a public good, not a commodity. Learn more doi.org/10.1111/1751-7915.70…
How does a methylotrophic yeast fine-tune methanol metabolism? Cai et al reveal high-res structures of two alcohol oxidase isozymes in Ogataea methanolica, showing distinct cofactor preferences & assembly into functional octamers:biotech protein production doi.org/10.1111/1751-7915.70…
PET waste is tough to recycle, but Barriuso’s group upcycled it into biodegradable PHAs using a hybrid approach: fast glycolysis engineered microbial consortium. By splitting tasks between microbes, they boost efficiency and valorize plastic waste. Read doi.org/10.1111/1751-7915.70…
Magnetospirillum MSR-1 produces magnetosomes, ie uniform, magnetic nanocrystals with huge biotech potential. Oxygen levels control their size: more O₂ → smaller crystals. Fine-tuning O₂ could boost scalable production of tailored magnetic nanoparticles. doi.org/10.1111/1751-7915.70…
Smarter bioreactors can better control how cells behave under real-world stress. Using real-time monitoring, Delvenne et al show how dynamic environments shape cell response and make biotech processes more reliable, scalable, and efficient. doi.org/10.1111/1751-7915.70…
Persister bacteria evade antibiotics by “hibernating” their ribosomes. A shift from active (70S) to inactive (100S) states defines persistence, & reversing this shift drives recovery. Targeting ribosome hibernation could help prevent infection relapse. doi.org/10.1111/1751-7915.70…
Bacterial vesicles could transform One Health—linking human, animal & environmental health with next-gen vaccines, diagnostics, and drug delivery. Tiny messengers, big impact. Read Arce-Rodriguez et al doi.org/10.1111/1751-7915.70…
ONE HEALTH: Turning pests into cures. Chen et al show that A cockroach-associated Streptomyces exhibits strong anti-Candida potential, revealing new antifungal compounds via multi-omics—opening ways to fight drug-resistant infections. Find more at doi.org/10.1111/1751-7915.70…
Decades of plant-focused breeding boosted yields, but reshaped (and often reduced) beneficial microbiomes. What if we bred plants and their microbiomes together? By combining rewilding & microbiome-aware genetics. An approach for climate-resilient crops. doi.org/10.1111/1751-7915.70…
Brüssow reviews COVID-19 antivirals. Remdesivir, molnupiravir & nirmatrelvir show variable benefits-greatest with early use in high-risk patients. Outcomes depend on timing, variants, patient context. Right drug,right time=better impact. Highly recommended doi.org/10.1111/1751-7915.70…