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Morgan Pfiffner @MorganPfiffner

MS in nutrition. I write about food and health. Editor-In-Chief of Study Summaries at Examine.com. Contributor for redpenreviews.org.

Joined January 2015
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In a new randomized controlled trial, skipping breakfast did not clearly worsen mood, sleepiness, or cognitive function in teenagers (13–15 y/o) when compared to regular low-GI breakfast (w/ or w/o nitrate supplementation). nature.com/articles/s41538-0…
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This crossover trial found that a vegan diet, but not a Mediterranean diet, substantially reduced people's estimated intake of advanced glycation end products (AGEs). I think the jury is still out on the harms of AGEs, but interesting data nonetheless. pubmed.ncbi.nlm.nih.gov/3917…
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Morgan Pfiffner retweeted
Dr. Travis Masterson, PhD@NutritionCues
29 Aug 2024
🔎New study out from our Dartmouth team! 🔍 🧬Genetics interact with cue reactivity!🧬 onlinelibrary.wiley.com/doi/… "Each FTO risk allele was associated with a 30% increase in [intake]... Food cue exposure exacerbated associations between the FTO variant with gummy candy [intake]."

Genetic associations with consumption of palatable foods in the absence of hunger in response to...

Objective The objective of this study is to evaluate obesity-related genetic factors in relation to excess consumption and assess if food cues modify associations. Methods Children (9–12 years) co...

onlinelibrary.wiley.com
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In an article for @Examinecom I wrote about exercise-related energy compensation (ExEC), a phenomenon in which exercise burns fewer calories than expected. examine.com/research-feed/st…
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A new study analyzed a single dataset on red meat and mortality 1,208 different ways In an article for @Examinecom, I discuss why researchers did this, what it tells us about epidemiology, and why it doesn't tell us much about red meat and health. examine.com/research-feed/st…
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I found another AI-generated garbage diagram in a scientific journal. It’s entirely gibberish and features anatomically incorrect limbs with too many bones. ncbi.nlm.nih.gov/pmc/article…
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Follow-up: I’ve received notice that the journal is retracting this study, due to the above graphic and a number of concerning data irregularities pointed out by @MicrobiomDigest and @TKesteman on PubPeer.
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In case anyone is interested, at @Examinecom we have a guide called “How to Read a Scientific Study”. It’s a great surface-level resource for catching study limitations that aren’t as obvious as AI-generated mutant leg bones. examine.com/guides/how-to-re…
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Most people who go on diets see weight loss plateau as time goes on. Could switching up your diet prevent this? Maybe not. In a new study, diet-induced weight loss showed expected slowing, even as folks changed diets after 6 months (from low-fat to low-carb, or vice versa).
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It's still possible that diet switching has some minor benefits (it may partially inhibit regain), but can't really say for sure until there's a similar RCT with a non-switching control group. Reference: pubmed.ncbi.nlm.nih.gov/3868…

Switching diets after 6-months does not result in renewed weight loss: a secondary analysis of a...

Weight change trajectory from diet and lifestyle interventions typically involves rapid weight loss followed by a weight plateau after approximately 6 months. Changing from one weight-loss diet to...

pubmed.ncbi.nlm.nih.gov
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Does exercise help with depression? And which types help the most? In my new article for @Examinecom I wrote about a curious meta-analysis on the topic: examine.com/research-feed/st…
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I think this is objectively wrong (sorry Brady!). There is extensive data that smoking increases mortality risk substantially more than sitting: pubmed.ncbi.nlm.nih.gov/3025…

Evaluating the Evidence on Sitting, Smoking, and Health: Is Sitting Really the New Smoking? - PubMed

Sitting has frequently been equated with smoking, with some sources even suggesting that smoking is safer than sitting. This commentary highlights how sitting and smoking are not comparable. The most...

pubmed.ncbi.nlm.nih.gov
Brady Holmer
@Brady_H
2 Apr 2024
"Sitting is the new smoking." I think sitting is worse. Based on some analyses, the mortality risk reduction associated with being physically active (-66%) is greater than the risk reduction associated with not smoking (-38%): sciencedirect.com/science/ar…
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Sitting time and physical activity can be disentangled, as in the 45 and Up Study. pubmed.ncbi.nlm.nih.gov/3102…
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Is yogurt overrated for metabolic health? In a new 16-week randomized controlled trial, yogurt was not clearly better than milk at improving health metrics like body fat, liver fat, blood pressure, blood lipids, or insulin resistance. pubmed.ncbi.nlm.nih.gov/3823…
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I’m excited to share my review of the book How Not to Diet! HNTD makes a myriad of claims — with haphazard scientific accuracy — to rationalize an overly complicated diet that nonetheless seems conducive to weight loss and fairly healthy. redpenreviews.org/reviews/ho…

Red Pen Reviews@redpenreviews
1 Feb 2024
New Review! How Not to Diet: The Groundbreaking Science of Healthy, Permanent Weight Loss By Michael Greger Written by @MorganPfiffner One of our most requested books. redpenreviews.org/reviews/ho…
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In a new clinical trial, a Mediterranean diet led to impressive improvements in IBS symptoms (despite no difference in FODMAP or fiber intake). I think this could be a big step forward for IBS management. Check out my article on study for @Examinecom. examine.com/research-feed/st…
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Credit to @FeliceJacka and colleagues at the @foodmoodcentre for this research.
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In a new analysis from the Look-AHEAD trial, achieving remission of type 2 diabetes was associated with a 40% lower risk of CVD. Remission was more likely in the lifestyle intervention (diet exercise) group. pubmed.ncbi.nlm.nih.gov/3823…
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“Using the structured approach to assess concordance, 15 (19.0%) out of 79 analysed diet-disease outcome pairs were concordant.”
Nick Krontiris
@nick_krontiris
10 Jan 2024
In line with findings of previous studies from the same group, this meta-research study suggests that on average, randomized controlled trials and cohort studies are likely to have similar effect estimates.
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A cohort study with 59,033 women found that eating pan-fried red meat was associated with a lower risk of T2 diabetes... ...if participants cooked their meat in vegetable oil. (sharing bc I found it interesting, but I wouldn't read too much into it) ncbi.nlm.nih.gov/pmc/article…
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