Bio - logy. Mutations, TADs, and gene regulation in development. All the good stuff. Tweets by @mphan_236 and lab members.

Joined January 2015
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MundlosLab retweeted
(1) Chromatin/cancer paper alert! We've unraveled how genotoxic anticancer drug impacts the chromatin structure of human cells. Using Hi-C, ChIP-seq, and RNA-seq, we've explored the changes in chromatin architecture triggered by doxorubicin and ICRF193. mdpi.com/2073-4409/12/15/200…
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MundlosLab retweeted
Excited to share our story on how enhancers repositioning leads to disease-associated gene mis-expression during development out in @NatureComms 🧬🐁🤓 I couldn't be happier to have teamed up with @Giulia_Cova on this one! @MundlosLab 👇 rdcu.be/c73nV

And it’s officially out @NatureComms!!Couldn’t be happier 😃🥳!! A long way, but definitely worthy!!Thanks to my amazing partner-in-crime @GJuliane_ 🤗, all the authors, the reviewers, and to everyone that has been part of this journey 🤗 so grateful!! nature.com/articles/s41467-0…
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MundlosLab retweeted
And it’s officially out @NatureComms!!Couldn’t be happier 😃🥳!! A long way, but definitely worthy!!Thanks to my amazing partner-in-crime @GJuliane_ 🤗, all the authors, the reviewers, and to everyone that has been part of this journey 🤗 so grateful!! nature.com/articles/s41467-0…

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MundlosLab retweeted
🧬 Want to dissect the gene regulatory function of long non-coding RNAs using #genomicengineering #syntheticbiology? Join the lab of @StefanMundlos / @MundlosLab & our #IMPRS-BAC #gradschool! Apply today! 👉 molgen.mpg.de/4567460/Mundlo…

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MundlosLab retweeted
Researchers @MeloUira @StefanMundlos @MundlosLab @VingronLab characterize structural variations (SVs) in a cohort of individuals with complex genomic rearrangements and investigate their impact on gene expression and the 3D chromatin architecture. go.nature.com/3VgGeAM
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28 Nov 2022
Way to go! Congrats @Alessa_Ringel 🥳🥳🥳
Last week we hosted the GOA Young TAD Award presentations. They were all amazing and the scoring was very tight! We are excited to announce the winner was @Alessa_Ringel 👏👏👏
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MundlosLab retweeted
🦔 Looking for a #PhD position & interested in investigating how the hedgehog got its spines? Join the lab of @StefanMundlos / @MundlosLab & our #IMPRS-BAC #gradschool! Apply today! 👉 molgen.mpg.de/4567427/Mundlo…

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MundlosLab retweeted
Interested in gene regulation in disease? Stay tuned for @mrmikerobson1´s lab opening @BIMSB_MDC in April 2023.
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30 Sep 2022
The latest Mundlos lab evolutionary adventure in gene regulation continues.. Big congratulations to @Alessa_Ringel & @mrmikerobson1! Check out the tweetorial for the highlights ⬇️
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MundlosLab retweeted
Job alert Postdoc: you are a molecular biologist and interested in gene regulation? Study how lncRNAs work in regulating genes in development. Use cutting edge technologies including synthetic genomics and large-scale genomic engineering. Contact me. molgen.mpg.de/Development-an…
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30 May 2022
Congrats everyone, especially our very own @KraftKaterina & @Andreas_Magg 🍾🥂 A must-read for all 3D- & Polycomb-enthusiasts!
Thank you @KatieEYost @HowardYChang @SedonaMurphy @Andreas_Magg @YichengLong @ABoettiger @StefanMundlos Tom Cech Polycomb-mediated genome architecture enables long-range spreading of H3K27 methylation | Proceedings of the National Academy of Sciences pnas.org/doi/10.1073/pnas.22…
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MundlosLab retweeted
Thanks so much to everybody for support in this #ERCAdG endeavor! It has been a tough competition. I see it as a special honor that my project was viewed as "ostentatiously overambitious" by a reviewer. Peer reviews are so much fun! 😂
🍾 Congratulations! 🎉 For a a research project on the genomics of evolution, or “how bats learned to fly”, our researcher @StefanMundlos / @MundlosLab has been awarded a prestigious @ERC_Research Advanced Grant #ERCAdG molgen.mpg.de/4491702/
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Anlässlich ihrer Jahresversammlung zeichnet die Leopoldina ForscherInnen für ihre hervorragenden wissenschaftlichen Leistungen aus. Mehr: leopoldina.org/presse-1/nach… @CoBaStiftung
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MundlosLab retweeted
I am excited to announce the publication of TADA, a tool to prioritize pathogenic CNVs @GenomeBiology! TADA annotates CNVs with respect to the affected regulatory environment and computes a pathogenicity score indicating their functional impact. genomebiology.biomedcentral.…
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14 Feb 2022
Check out our new @biorxivpreprint! A bona fide Mundlos Lab's study looking at structural variations leading to gene dysregulation @ the Lbx1/Fgf8 locus. An impressive effort lead by @Giulia_Cova & brought to the finish line by @GJuliane_ #preprint #3DGenome
Extremely happy to share the preprint of my work from my time in the @MundlosLab! A novel conceptual framework where combination of gene misexpression and dosage occurs upon structural variations that involve the Lbx1/Fgf8 locus and its 3D organization. biorxiv.org/content/10.1101/…
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14 Feb 2022
@Giulia_Cova is now a post doc in NYC @nyulangone. Feel free to reach out to her if you have any questions!
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MundlosLab retweeted
🦇 Join the lab of @StefanMundlos / @MundlosLab / @der_bri to find out how bats learned to fly! To uncover the complex changes in its genome, apply as a #PhD student & join our #IMPRS-BAC research school! 👉 molgen.mpg.de/3931585/Mundlo…
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