A collaborative group for early- and mid-career faculty who study nuclear receptors. Advancing science and career development.

Joined December 2020
7 Photos and videos
NR IMPACT retweeted
For #WomensHistoryMonth, @zmadak is honoring JES Associate Editor (bit.ly/39Ubs9D), @Prof_Riggins, for her knowledge and mentorship. @womensday #IWD2023 #InternationalWomensDay
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NR IMPACT retweeted
For #WomensHistoryMonth, @emiliampinto is honoring @Katja_K_Vassi, who is serving on our Annual Meeting Steering Committee, Endocrine Cancers SIG, #JCEM Editorial Board, for her passion and dedication to adrenocortical disorders. @womensday #IWD2023 #InternationalWomensDay (1/2)
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For #WomensHistoryMonth, @mjsikora is celebrating both @Prof_Riggins and @zmadak for their years of colleagueship. He admires their selfless contributions of time, energy, and support for trainees and faculty. @womensday #IWD2023 #InternationalWomensDay
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Fantastic job by @ZheqiL and others in the lab. Thanks @mjsikora @JCarrollLab for help. Maybe @NR_IMPACT can take this on for other receptors, other tumor types? In the meantime pls provide #feedback 🙏 #bcsm
Please RT: ER/E2/breast cancer. We are seeking #crowdsourced datasets and opinions. We curated 136 published datasets, processed with one pipeline and made a browser to visualize E2-induced expression and ER binding. Feel free to try it out estrogene.org/ 🧵
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NR IMPACT retweeted
Excited to share a new @biorxivpreprint from the lab! In this study, we show that RXRα ligands activate transcription of Nurr1-RXRα heterodimers through a mechanism distinct from classical pharmacological #nuclearreceptor activation. doi.org/10.1101/2022.11.08.5… 🧵 @NR_IMPACT

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NR IMPACT retweeted
What a cool story from @NR_IMPACT member Doug Kojetin and colleagues dissecting Nurr1-RXRα regulation. NMR, transcriptional control, small molecules...what more can you ask for 😁
Molecular basis of ligand-dependent Nurr1-RXRα activation biorxiv.org/content/10.1101/… #NuclearReceptors #NMR #TR-FRET
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9 Nov 2022
Estrogene is an outstanding new resource to query the current state of knowledge of the ER-alpha transcriptome and cistrome in breast cancer models - fair warning that you might lose a day looking for your favorite genes! We're intrigued by the idea of expanding this though...

ALT Math Zack Galifianakis GIF

Fantastic job by @ZheqiL and others in the lab. Thanks @mjsikora @JCarrollLab for help. Maybe @NR_IMPACT can take this on for other receptors, other tumor types? In the meantime pls provide #feedback 🙏 #bcsm
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NR IMPACT retweeted
Please consider applying for our Summer Undergraduate Research Experience in Toxicology at the University of Illinois. This program is designed for under-represented undergraduate students that are interested in Toxicology. Due date Feb 15, 2023. vetmed.illinois.edu/suretox/
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NR IMPACT retweeted
Our next step towards a clinical-grade #CAMKK2 inhibitor. Team effort led by @dhdrewry. @Dr_CaMKkinase @MetSigLab @anwarmedc @Chenchu48450284 @AwadDom @donaldmcdonnell
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NR IMPACT retweeted
See @LindseySTrevino discuss her experiences as a Latina in #endocrinology, and how important the support she received by peers in @TheEndoSociety's FLARE program has been to her career: bit.ly/3D5Lv7L #HispanicHeritageMonth
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13 Oct 2022
NR IMPACT is thrilled to welcome 5 new members! These scientists increase IMPACT's collective expertise in metabolism, structural biology and ligand binding, neuropharmacology, and cancer biology. nrimpact.com/members Without further ado... 🧵1/7
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.@AyeshaShafi14 is at @USUhealthsci. The Shafi Lab is focused on defining mechanisms and biomarkers of therapeutic resistance in patients with advanced prostate cancer (PCa) with the goal to develop better treatment strategies. usuhs.edu/node/122655 6/7

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We're thrilled to have this group of outstanding nuclear receptor scientists join NR IMPACT! We look forward to supporting their career development, and to leveraging their unique expertise. Welcome! 7/7

ALT Jimmy Fallon Celebs GIF

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NR IMPACT retweeted
#HispanicHeritageMonth Featured Member | @LindseySTrevino an Outstanding Abstract Award winner, speaks on her experience as one of the few Latinas during her career, and the support she received from peers in FLARE (bit.ly/2N5iKxV): bit.ly/3T2DqWr
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NR IMPACT retweeted
I was a guest on "The Scientist Speaks" podcast from @TheScientistLLC "What Comes Up Must Go Down: Maintaining Hormone Balance Through RNA Decay" bit.ly/3CsW9DT Huge thanks to @NSpahich for the invite and fun chat about my lab's research here at @CUAnschutz @rnabioco
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