Biosensor engineer
Joined March 2021
- Tweets 246
- Following 269
- Followers 434
- Likes 839
11 Photos and videos
Yusuke Nasu retweeted
台湾ー日本の神経科学者のための交流会です。一般参加者を受け付けています！
演題募集：2026年6月30日（火）締切
事前参加登録：2026年7月15日（水）締切
場所：Academia Sinica（台北）
8月24 - 25日 開催 2026台日神経科学研究者交流会
jnss.org/academic-events?id=…
1
3
4
560
Yusuke Nasu retweeted
Excited to announce a powerful new one-two punch for voltage imaging from our lab and collaborators! In two new preprints, we introduce ASAP6c for high-throughput population spike-recording, and ASAP7yfor deep, subthreshold 2P imaging.
🧵 1/14
5
52
189
19,207
Yusuke Nasu retweeted
May 22
Where a signaling protein lives matters as much as what it does. Our new tool lets you interrogate this one compartment at a time. We built TerminaTOR, a genetically encodable inhibitor that silences mTORC1 at subcellular locations.
1
7
52
5,035
Yusuke Nasu retweeted
May 17
Hope to see many local friends at Q Microbio at Academia Sinica tomorrow!
sites.google.com/view/q-micr…
1
2
250
Yusuke Nasu retweeted
🔬Publication - by Dr. Steven Lin @NatureComms
The newly established #genome-wide #CRISPR screening platform identified key regulators of #NK #cell functions, suggesting potential engineering targets for more potent NK #cancer #immunotherapy. doi.org/10.1038/s41467-026-7…
#biochem
3
4
349
Yusuke Nasu retweeted
An inspiring lecture on the history of Kamiokande, Kamland, and super-Kamiokande. We look forward to the launch of hyper-Kamiokande!
3
7
294
Yusuke Nasu retweeted
Excited to share that our AzoTag paper is now out in @NatureChemistry! 🥳
We demonstrate de novo chemo-optogenetics through the rational design of photoresponsive small molecules and selection of their artificial protein binding pairs.
nature.com/articles/s41557-0…
5
36
168
13,786
Yusuke Nasu retweeted
[Please RT]
Hiring: Research Technician II – Inoue Lab, WashU
We build new optical sensors AND apply them in vivo to study brain disorders.
Looking for someone excited about: stereotaxic surgery & mouse handling, neural circuit imaging
Great prep for PhD / MD-PhD applicants.
1
18
49
5,284
Yusuke Nasu retweeted
Apr 6
Online now: Astrocytic glucose metabolism regulates the survival of newborn hippocampal neurons in the adult brain dlvr.it/TRv9GD
1
34
131
8,569
Yusuke Nasu retweeted
Took a break from science-posting for several months (will explain later), but excited to finally discuss some recent work from the lab.
First up, a new solution to the old problem: How to engineer proteins to bind to a natural metabolite of interest, in this case biliverdin
1
4
30
2,571
Yusuke Nasu retweeted
Mar 18
Today we report single-cell APEX-seq (scAPEX-seq) — a new method for unbiased mapping of *subcellular* transcriptomes at single-cell resolution. This approach reveals cell states that are not detectable by standard scRNA-seq, and enabled us to identify regulators of CAR T function that improve solid tumor killing.
biorxiv.org/cgi/content/shor…
3
121
531
41,532
Yusuke Nasu retweeted
Congratulations to Dr. Makoto Shirakawa @MakotoShirakaw2 on receiving the JSPP Young Investigator Award! The award ceremony was held on March 14 in Tokyo.
1
10
44
1,879
Yusuke Nasu retweeted
Mar 15
Excited to share our new paper on GRAB_PGE2-1.0, the first genetically encoded fluorescent sensor for monitoring spatiotemporal prostaglandin E2 (PGE2) dynamics in vivo! It enables real-time imaging in cultured cells, acute brain slices, and living mice.
2
17
129
6,303
Yusuke Nasu retweeted
Mar 13
私の所属する研究所が４０周年を迎えるにあたり、関連分野のリーダーを招いてシンポジウムを開催します。定量生物・生物物理関連では James Ferrell, Michale Elowitz, Wendell Lim らが登壇してくれます。三日間の濃密なプログラムです。ぜひお越しください。
4
14
667
Yusuke Nasu retweeted
Excited to share our new preprint with @fbayashi_T!
We developed a boosted PURE-based cell-free FADS platform for rapid protein evolution.
Using this platform, we evolved highly robust SP6 RNA polymerases and engineered split variants that sense diverse biomolecular interactions.
Efficient cell-free evolution of RNA polymerases by droplet microfluidics biorxiv.org/content/10.64898… #biorxiv_synbio
17
34
7,404
Yusuke Nasu retweeted
Our collaborative study with Yasui lab @sciencetokyo_ja is out in @ScienceAdvances ! With gRNA/GeNL tagging, we showed that cancer-derived small EVs can reach and be concentrated in urine via transcytosis, providing rationale for urinary liquid biopsy. science.org/doi/10.1126/scia…
1
7
44
3,958
Feb 22
羊土社『実験医学』3月号にて、Academia Sinicaおよび私の研究室の紹介記事を寄稿しました。研究環境や日々の取り組み、Academia Sinicaで研究を行う魅力についてまとめています。ご関心のある方にお読みいただけましたら幸いです。
Academia Sinicaでは各Institute（大学の学部に相当）でほぼ毎年PIの公募が行われていますが、それに限らず、大学院生やポスドクとして挑戦できる機会も数多くあります。近年は、欧米でポスドクをされている日本人研究者や、日本で研究を進めてこられた方々の着任も増えており、日本との距離も年々縮まっていると感じています。
本稿が、学生・ポスドク・PI志望の方を含め、海外での研究という選択肢を考えるきっかけになれば嬉しく思います。
Feb 21
6
18
3,701
Yusuke Nasu retweeted
📢 Applications are open! Join us @HHMIJanelia to explore next-gen fluorescent proteins, biosensors, imaging advances ML/computational approaches to accelerate design.
🛏️ Meals & lodging covered
Apply by May 21 ➡️ janelia.news/FPS26
@HHMIscience @ERSchreiter @agtebo
7
43
8,859
Yusuke Nasu retweeted
Feb 10
Come join us at the Quantitative Microbiology Symposium this May in Taipei!
We’ve invited outstanding researchers working at the interface of the mathematical sciences and microbiology.
For details and registration, see: sites.google.com/view/q-micr…
3
8
673
Yusuke Nasu retweeted
Feb 10
🧪🧬 New preprint!
What if the same biosensor could reveal how cysteine is regulated across life domains?
We introduce Cystector, a genetically encoded fluorescent biosensor for real-time cysteine monitoring in living cells.
biorxiv.org/content/10.64898…
🧵A thread ⬇️
2
11
57
4,756