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Neufeldt Lab @NeufeldtLab

Organic and organometallic research at Montana State University. Established 2016. Student-run lab page.

Joined July 2017
  • Tweets 81
  • Following 220
  • Followers 933
35 Photos and videos
Not that we're huge social media users, but we'll be migrating to Bluesky. Latest: C2 selective cross-coupling of 2,4-dichloropyrimidine doi.org/10.1021/jacs.4c17020 (our "holy grail" for inverting site selectivity) and Sharon receives a PECASE (Biden admin.) tinyurl.com/yc3de6e6

C2-Selective Palladium-Catalyzed C–S Cross-Coupling of 2,4-Dihalopyrimidines

Under most conditions, 2,4-dihalopyrimidines undergo substitution reactions at C4. Here we report that Pd(II) precatalysts supported by bulky N-heterocyclic carbene ligands uniquely effect C2-selec...

pubs.acs.org
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Congrats to Oliver, Albert, Collin, Nate, And Calvin on publishing on a novel C2 selective C–S cross-coupling of 2,4-dichloropyrimidine. Amazing work achieving unconventional selectivity. pubs.acs.org/doi/10.1021/jac…

C2-Selective Palladium-Catalyzed C–S Cross-Coupling of 2,4-Dihalopyrimidines

Under most conditions, 2,4-dihalopyrimidines undergo substitution reactions at C4. Here we report that Pd(II) precatalysts supported by bulky N-heterocyclic carbene ligands uniquely effect C2-selec...

pubs.acs.org
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We had a great time "flooding" the department on Halloween for the GSA hosted costume contest. Thank you to all who voted and help us secure our second group costume win.
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Check out what's new happening in our department!!! chemistry.montana.edu/newsle…

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We teach oxidative addition of ArX at Pd(0) as a 3-centered TS, but it's more complicated. Understanding the mechanistic nuances has implications for site-selective cross-coupling. Congrats Matt and Albert on your epic investigation now in @J_A_C_S! pubs.acs.org/doi/10.1021/jac…
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Neufeldt Lab retweeted
Synthesis Workshop@MatthewHorwitz1
29 May 2024
Today on The SW Pod with @aplooby28 we journey into the mechanistic world of transition metal catalysis with Prof. Sharon Neufeldt @NeufeldtLab @montanastate!! Spotify: open.spotify.com/episode/19S… YouTube: youtu.be/PmKiymSNM3I If you like these episodes, RT for visibility!
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As the semester comes to an end, we want to thank our wonderful undergrads Riley, Zach and Daniel for all the work they have put in over the semester. Special shoutout to Daniel for winning a poster award.
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Congrats to Nate and Jake for publishing "Mechanistic Origin of Ligand Effects on Exhaustive Functionalization During Pd-Catalyzed Cross-Coupling of Dihaloarenes" in ACS Catalysis. pubs.acs.org/doi/10.1021/acs…

Mechanistic Origin of Ligand Effects on Exhaustive Functionalization During Pd-Catalyzed Cross-Co...

We describe a detailed investigation into why bulky ligands─those that enable catalysis at “12e–” Pd0─tend to promote overfunctionalization during Pd-catalyzed cross-couplings of dihalogenated...

pubs.acs.org
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From firery redox reactions to golden products: @grace_ibsen column's is a chromatic journey through the vibrant world of reactions. @Biotage
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The Neufeldt lab is looking to hire 1-3 new grad students to start in fall 2024 to work on mechanistic organometallic research. We like to ask the questions "why?" and "how?" and then "can we make it do something different?" neufeldt-chemistry.com/
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Our lab is currently funded by the NIH and NSF. Experimental or computational background/interests welcome. Please email Sharon directly with questions (contact info here: tinyurl.com/3bx37kmm)
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MSU GSA held a lab coustume contest, and were lucky enough to win!!! We have to start planing our next group costume.
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Today we had the honor of listening to Oliver give his 4th year seminar. It was great to hear what you've done over the year, and excited to see what is to come!
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Yesterday, the Neufeldt Lab participated in the department Fun run 5K. We were excited to show some lab pride!
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Congrats to Oliver for presenting at GRS2023
Angie R Angeles@angierangeles
23 Jul 2023
A great way to end day 3 with more amazing student presentations ⁦@ACSorganic⁩ #GRS2023: Hillary Nguyen (Colorado State Univ), Oliver Jackson (Montana State Univ), David Cabanero (Columbia Univ)! ⁦@AndyMcNally367⁩ ⁦@RovisGroup⁩ ⁦@NeufeldtLab⁩
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Neufeldt Lab retweeted
Joan Broderick@joanbroderick
13 May 2023
So happy for our newly-minted Associate Professors with tenure. They are passionate and inspiring, and just good people. I’m happy to call them colleagues. Roland Hatzenpichler, Sharon Neufeldt, and Nick Stadie. @environmicrobio @NeufeldtLab
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Neufeldt Lab retweeted
Nicholas Ball@ballnchemist
16 Jun 2023
20 years of Sanford @Sanford_Lab Note: not even close to everyone:)
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As the semester comes to a close, we would like to congratulate Dr. Sharon Neufeldt on getting tenure. You have worked very hard and deserve it.
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Congratulations to such a hard working group! They were able to find a novel, ligand free, trifliate selective cross coupling method in chloro- and bromo-aryl triflates system. doi.org/10.1002/asia.2023000…

Triflate‐Selective Suzuki Cross‐Coupling of Chloro‐ and Bromoaryl Triflates Under Ligand‐Free...

“Ligand-free” room-temperature conditions for Pd-catalyzed Suzuki couplings of haloaryl triflates give selectivity for triflate over chloride or bromide. For chloroaryl triflates, triflate selectiv...

aces.onlinelibrary.wiley.com
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Playing Jeopardy in group meeting to become aquatinted with different topics that are important to our group, and have a little fun while doing it.
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