An #openAccess journal, owned by CMA, published by Wiley. The mission of #Neuroprotection is to build a platform for people who care about neuroprotection.
Joined December 2022
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Happy New Year from #Neuroprotection! We are excited for what is to come in 2026. May it be a successful one for all of you as well.
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🧠 Can ursodeoxycholic acid (UDCA) help combat neurodegeneration?
This review in #Neuroprotection highlights evidence that UDCA:
✅ Restores mitochondrial function ✅ Reduces oxidative stress & neuroinflammation ✅ Protects neurons in PD and AD models
📄 doi.org/10.1002/nep3.70039
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Early clinical studies in Parkinson's disease are encouraging, but larger trials are needed.
#Neuroprotection #ParkinsonsDisease #AlzheimersDisease #Neuroscience #UDCA #Neurodegeneration
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Can #neuroprotection begin after recanalization?
Schneider et al. report that intravenous #rapamycin administered immediately after recanalization:
✅ Reduced infarct volume ✅ Improved neurological outcomes ✅ Enhanced somatosensory function
doi.org/10.1002/nep3.70035
#stroke
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Notably, these benefits occurred without significant changes in CBF, BBB permeability, or edema, suggesting a perfusion-independent mechanism.
The findings support further investigation of #rapamycin as an adjunct therapy alongside #reperfusion treatments for #ischemicstroke.
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🧠 New in #Neuroprotection
Lei et al. propose a novel microglial compensation-depletion framework for Alzheimer's disease. [1/2]
📖 doi.org/10.1002/nep3.70037
#Alzheimers #Microglia #Neuroinflammation #Neuroscience
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#Microglia may initially protect against Aβ pathology, but depletion of this compensatory capacity could mark a critical tipping point toward #neurodegeneration and cognitive decline.
#Alzheimers #Neuroinflammation #Neuroscience
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Neuroprotection retweeted
May 19
🧠NP journal: 🇸🇪 Lund Univ study finds Environmental Enrichment (EE) breaks the link between infarct size & chronic inflammation.
✅ Boosts sensorimotor recovery
✅ Highlights TREM2 microglia as key players
📄More: einpresswire.com/article/912…
via @ein_news #Stroke #Neuroprotection
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Neuroprotection retweeted
Take-home messages from the great talk by @johanna_ospel on the evolving concept of the core/penumbra model in 2026.
Thank you for this insightful and thought-provoking presentation @ESOstroke
#ESOC2026 #Stroke
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Neuroprotection retweeted
Day 2 of #ESOC2026 has started. Looking forward to more inspiring talks and posters. Don't miss joining our session "Brain on fire - Inflammation in ICH as a potential treatment target" at 5 PM in room Sydney.
#VoiceOfStroke #Stroke #StrokeResearch #ICH
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Neuroprotection retweeted
This is 🔥
A next-gen GLP-1/GIP agonist outperforms tirzepatide in a Parkinson’s model better brain penetration neuroprotection anti-inflammatory effects.
We’re not just treating metabolism anymore… we’re crossing into neurodegeneration.
frontiersin.org/journals/end…
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Neuroprotection retweeted
Selective intra-arterial cooling indicates potential safety benefits but no sufficient functional improvement in stroke patients treated with endovascular thrombectomy 🧠
@ESOstroke #StrokeTreatment #Neuroprotection #ESOC2026
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Neuroprotection retweeted
Now live at #ESOC2026: Acute treatment in intracerebral hemorrhage
#VoiceOfStroke #Stroke #StrokeResearch #ICH
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Neuroprotection retweeted
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Neuroprotection retweeted
Looking forward to a passionate exchange at #ESOC2026. Honored to be part of the Session: “Brain on fire – Inflammation in #ICH as a potential treatment target”. 🧠🤩
I am honored to be invited to present at the #ESOC2026 meeting in Session ID SS17: "Brain on fire – Inflammation in #ICH as potential treatment target"
where we will be discussing #inflammation and also other treatment targets for intracerebral hemorrhage.
#Stroke #VoiceOfStroke
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Neuroprotection retweeted
#ESOC2026 is about to start. Join the Welcome Session & Large Clinical Trials.
#VoiceOfStroke #Stroke #StrokeResearch #ICH
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Our editorial board member @ZilleMarietta in action!
I am honored to be invited to present at the #ESOC2026 meeting in Session ID SS17: "Brain on fire – Inflammation in #ICH as potential treatment target"
where we will be discussing #inflammation and also other treatment targets for intracerebral hemorrhage.
#Stroke #VoiceOfStroke
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We also welcome manuscripts on #neuroprotection in intracerbral hemorrhage. #ICH
Delighted to participate in the ICH Academy Meeting (IAM) which is happening today prior to the official start of #ESOC2026. It is wonderful to have this dedicated meeting on #ICH.
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Our editorial board member @ZilleMarietta will be at #ESOC2026 over the next few days. If you are interested to chat with her about #Neuroprotection, #stroke, #ICH or related topics, don't hesitate to get in touch with her.
A few more minutes to Maastricht to participate in the 12th European Stroke Organisation Conference #ESOC2026. Looking forward to the news on the frontiers of clinical and basic #stroke research.
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🧠 Is aromatase a therapeutic target in stroke? [1/2]
Read more:
doi.org/10.1002/nep3.70033
#Stroke #Neuroprotection #Estrogen #Neuroscience #TranslationalResearch
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🔹 #Aromatase expression increases after focal cerebral ischemia
🔹 Suggests endogenous neuroprotective response
🔹 But overexpression did not improve functional recovery
🔹 Aromatase inhibition did not worsen outcomes
Important insights into estrogen-related #neuroprotection.
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