Neuropathologist; Cancer genomics research; Assistant Professor, Harvard Medical School @BrighamWomens @BWHPath

Joined August 2012
14 Photos and videos
Thanks for including me in this great work!
We’re excited to share our study looking at molecular classification and survival of 4,400 #gliomas @NeuroOnc A huge team effort over the years @MGBNeurosurgery @BWHNeurosurgery @DanaFarber, here’s what we found. 1/10 academic.oup.com/neuro-oncol…
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Excited to share that our paper on a foundation AI model for cancer prognosis and pathology diagnosis is published in Nature today. nature.com/articles/s41586-0… @HarvardDBMI @NIH @NIGMS @CDMRP @AmericanCancer #AI #DigitalPathology

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Not before your pathologist does! Important opportunity for pathologists and other diagnosticians to communicate their results directly to patients and explain results. Patients need to advocate for this as it’s not currently supported by insurance. #pathology
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When you see your health test results before your doctor? It's the law. My latest: wsj.com/health/wellness/your… via @WSJ
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Glad to finally have our work on ROS1-rearranged gliomas in diverse age groups published! #Neuropath #PathTwitter #pathX #pathology sciencedirect.com/science/ar…

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Thanks for including me in this exciting work!
Excited to share our new paper: AI and digital pathology enable real-time diagnoses and molecular subtype predictions during cancer surgery. cell.com/med/fulltext/S2666-… @MacNasrallah @JuzZ_AI_Mopho ChengCheTsai @NeuropathDM @ElianaMarostica @KeithLigon5 @Jeff_golden1 @HarvardDBMI
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Partially demyelinated axons of the cauda equina in the setting of Powassan Infection, presented by our Clinical Fellow, Dr. Kate Krause @pathonthewing #neuropathology #neurotwitter #infectiousdisease
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MALIGNANT PERIPHERAL NERVE SHEATH TUMOUR. Underlying NF1. IHC: SOX10, H3k27me3. NB: spindle-epithelioid cells with pale amphophilic cytoplasm; ovoid-round nuclei with moderate pleomorphism and conspicuous mitotic activity; variable collagenous-myxoid stroma.
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Rare example of chondroma arising in the dura (falx). Histo shows characteristic mature hyaline cartilage with increased cellularity and mild nuclear atypia. #pathology #PathTwitter #BSTpath #Neuropath
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Not all EMA tumors in the dura are meningiomas. Do you recognize this one? (EMA immunostain is shown for reference.) #pathology #PathTwitter #Neuropath #BSTPath
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Additional IHC (CD99 /des /SSTR2-) was highly characteristic of Intracranial Mesenchymal Tumor, FET::CREB fusion positive. EWSR1 FISH showed rearrangement. This particular case has a solid growth pattern with no myxoid stroma. #Neuropath #pathology #PathTwitter #BSTpath
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Can you diagnose in one cell? (Smear preparation from an enhancing deep white matter frontal mass in an older patient.) #Pathology #PathTwitter #Neuropath
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A good clue is the presence of lymphoglandular bodies in the background. Smear prep is probably the best way to diagnose CNS lymphoma at frozen section. Here is the accompanying H&E permanent section and CD20. #PathTwitter #pathology #Neuropath #hemepath
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Welcome to our new #PathMatch2023 AP/NP residents! Alicia Kenyon, MD from Sidney Kimmel Medical College at Thomas Jefferson Univ & Denis Smirnov, MD, PhD from Univ of California San Diego School of Medicine 🧠🔬#neuropath #PathTwitter @BrighamWomens @BostonChildrens @MGHPathology
Replying to @BWHPath
@BWHPath and @MGHPathology welcome 22 new residents to the Mass General Brigham Pathology Residency Program. We are thrilled that you will be joining us! Welcome to Boston. Congratulations to everyone who matched in pathology today! 🍾🎉 #PathMatch2023
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Nice example of a clear cell meningioma with the characteristic "blocky" collagen and absence of SMARCE1 expression.
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@BWHPath and @MGHPathology welcome 22 new residents to the Mass General Brigham Pathology Residency Program. We are thrilled that you will be joining us! Welcome to Boston. Congratulations to everyone who matched in pathology today! 🍾🎉 #PathMatch2023
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This was surgically removed from brain of a one year old. Source: ⁦@GreenJournal⁩ 🧵
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An infant presented w/an intra-axial frontal lobe lesion. A craniotomy for total resection was performed, and H&E of the brain lesion showed the following. What is your differential diagnosis? What stains would you get? #BWHPathCotW #BWHNeuroPathWinter 1/
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Hello and welcome to the Gross Case of the Week – Neuro Winter Edition! This week we have another case from autopsy. Can you guess what is pictured here? #GrossCOTW #NeuroWinter
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A pt presents w/an intracranial enhancing non-expansile mass in the parietal lobe and extending into the ipsilateral temporal lobe. Biopsies taken during a craniotomy show the following. What is your DDx? What additional studies would you do? #BWHPathCotW #BWHNeuroPathWinter 1/
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