Thankyou so much to all those who attended #4thphvcis2026 with the theme “CVD in women” full house with 300 attendees! The academic sessions were top notch with excellent talks & engaging discussions! special thanks to speakers from Canada & USA who stayed up so late to join us❤️

Good news! The much awaited 4th annual Pakistan valve and imaging conference is almost here! Excited to announce that this year the focus & theme is “disease in women” with a special Cardioob session in collaboration with ACC council for reproductive health and CardioOb!

🧠🫀 AI CCTA: from anatomy to actionable risk The CONFIRM2 registry takes a big step forward in showing what happens when AI-driven quantitative coronary CT angiography (CCTA) meets real-world clinical populations. 🔬 What’s new here? This isn’t just about detecting stenosis. 👉 AI enables automated, reproducible quantification of: ✔️ Total plaque burden ✔️ Non-calcified vs calcified plaque ✔️ High-risk plaque features Across large, multicenter datasets. 📊 Key insight Risk is not binary. Patients without “significant stenosis” can still carry: ⚠️ High plaque burden ⚠️ Adverse plaque phenotype And importantly: 👉 These features are strongly associated with outcomes, independent of traditional stenosis-based assessment. ⚡ Why this matters We’ve spent decades asking: “Is there a ≥50% stenosis?” But CONFIRM2 reinforces a shift toward: ➡️ Total disease quantification ➡️ Biology of plaque, not just lumen narrowing This aligns perfectly with the treat-to-plaque paradigm. ⚠️ The nuance AI is powerful—but: ✔️ Dependent on image quality ✔️ Sensitive to acquisition variability ✔️ Still requires clinical context 👉 Automation ≠ interpretation 🎯 Clinical implication AI-CCTA may: ✔ Improve risk stratification ✔ Identify patients missed by traditional metrics ✔ Guide earlier, more personalized prevention 🔮 Bottom line We are moving from: “Do you have a blockage?” ➡️ to “How much disease do you actually carry—and how dangerous is it?” AI doesn’t replace clinicians. But it’s starting to quantify what we’ve been underestimating for years.

#EHJIMP 👩‍🍼🌍Can we screen pregnant women for structural heart disease with handheld ultrasound? In PRESAP, POCUS matched standard TTE for valvular & congenital disease, though TTE was better for subtle LV dysfunction. Highly applicable in LMICs. 👉doi.org/10.1093/ehjimp/qyaf1…