Pediatric #neuromuscular doc, amateur scientist @URneuroscience, runner, chess enthusiast, dad. #Meliora
Joined September 2021
- Tweets 1,086
- Following 788
- Followers 856
- Likes 3,200
180 Photos and videos
Pinned Tweet
1 Jun 2025
New pod, who dis? Co-hosting with the incomparable @OligoclonalBand. Music by @zach_london. Drops monthly. Strap in.
Immature Brains: A Child Neurology Podcast rss.com/podcasts/immature-brโฆ via @rss
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Samuel Mackenzie MD PhD retweeted
Jun 12
I enjoy using IGV, but I need a more efficient tool for analyzing diploid genomes. So, I developed one for myself. It provides exceptional GPU acceleration, allowing me to uncover all essential information spanning six orders of magnitude. #bioinformatics #genomics #visualization
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Samuel Mackenzie MD PhD retweeted
Jun 5
Tryptophan is the tenured senior professor of amino acids. It negotiated a private parking spot, its own codon, and then spent the entire department budget on synthesizing serotonin.
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This is wild. Smells like a class action lawsuit to me.
May 22
Earlier this week I posted an example of a fake western blot provided by ThermoFisher to demonstrate the validity of a p53 antibody. I considered it an amusing curiosity. In fact ThermoFisher has systematically manipulated antibody validation data. Short Thread... ๐งต
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Samuel Mackenzie MD PhD retweeted
May 17
Surprised to discover that Thermo Fisher appears to show a fake western blot for the validation of one of their p53 antibodies. I've added a diagram to show the very similar bands. This does not appear to be one of the "published figures", but their own internal data.
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Samuel Mackenzie MD PhD retweeted
This is my favorite scene from The Bible.
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You too can donate! Support families who have lost a child. Childneurologyfoundation.org
Are you traveling to the @AANmember annual meeting today?
What a great time to listen to an incredibly goofy BONUS EPISODE of Immature Brains: A Child Neurology Podcast, where we pledge drive for @Child_Neurology with Kim Hindery!
rss.com/podcasts/immature-brโฆ @NotoriousEMG
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Samuel Mackenzie MD PhD retweeted
Are you traveling to the @AANmember annual meeting today?
What a great time to listen to an incredibly goofy BONUS EPISODE of Immature Brains: A Child Neurology Podcast, where we pledge drive for @Child_Neurology with Kim Hindery!
rss.com/podcasts/immature-brโฆ @NotoriousEMG
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Samuel Mackenzie MD PhD retweeted
Apr 7
Heartwarming: When Dan Orlovsky's autistic son, Madden, joined NFL Live and made everyone on set cry while highlighting Autism Awareness Day with his drawings.
You can just see how proud Dan is of his son.
What a special moment captured ๐ฅนโค๏ธ
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Samuel Mackenzie MD PhD retweeted
Mar 16
Here is our updated database of grants for early careers researchers in all fields.
It goes way beyond traditional NIH and NSF funding opportunities. We list 428 types of grants.
Download it here: research.jhu.edu/rdt/fundingโฆ
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Samuel Mackenzie MD PhD retweeted
this is what actual national suicide looks like btw
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Samuel Mackenzie MD PhD retweeted
Mar 16
We were told NIH funding cuts were about eliminating DEI.
But the data now shows grants are down across nearly every field of medicine: cancer, diabetes, mental health, brain disorders.
With the greatest cuts hitting Alzheimerโs research, down more than 50%.
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Samuel Mackenzie MD PhD retweeted
Mar 16
A deliberate erosion of the scientific enterprise begins by eroding the workforce.
In 2025 alone, the U.S. lost more than 10,000 STEM Ph.D.s across 14 federal agencies. The brain drain is real.
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Our final episode of season 1 is out! Thanks to all our listeners and to @kuntal_sen_ for joining us! See you again in June. @OligoclonalBand open.spotify.com/episode/1Aaโฆ
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Reposting this is probably rewarding some bot farm in Indonesia, but I donโt care.
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RT @JReinerMD: In the fall the administration held a press conference attended by President Trump, FDA Commissioner Makary, and HHS Sec Kenโฆ
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Samuel Mackenzie MD PhD retweeted
Feb 27
NIH is not issuing awards. You may think that it's because they it is coming up with new directions of research...The apposite is true.
Here is a graph showing how many fewer new funding opportunities that NIH has posted over time.
-91%, a trend that started on Jan 2025.
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Samuel Mackenzie MD PhD retweeted
Feb 26
Federal funding for US biomedical research is moribund.
Since October 1 2025, NIH is -80% in new grants and -70% in values (total dollars).
Labs are closing down and researchers are leaving science.
To what end?
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Samuel Mackenzie MD PhD retweeted
Feb 8
Todayโs American History Lesson: Puerto Rico has been part of the U.S. since 1898, and Puerto Ricans have been U.S. citizens since 1917 ๐ต๐ท ๐บ๐ธ
Weโve cheered many non-Americans at the #SuperBowl. Bad Bunny isnโt one of them.
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