Osteoarthritis and Cartilage, and Osteoarthritis and Cartilage Open - official journals of @OARSInews. Impact factor 9. co-EiCs: @AM_Malf & @ProfDavidHunter
Joined March 2018
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🔥 Just out!
The first of OAC's Osteoarthritis "Fundamental series" covers #diagnosis and #assessment
A clinician’s diagnosis is a vital step to facilitate access to and engagement
with treatment.
Read more from Lauren King and Abhishek Abhishek here: oarsijournal.com/article/S10…
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🔥 New this month!
What are the effects of Sustained Release Calcium Butyrate (SRCaBu) on gut microbiome composition and function in hand OA patients?
Read for free from Merel Hartog et al. - oarsijournal.com/article/S10…
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🩺🤖 How close are we to seeing Generative AI in everyday osteoarthritis care?
Read more from Fairley et al. in this month's issue: oarsijournal.com/article/S10…
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📈Knee arthroplasty in OECD countries has hit a tipping point
New study by Backes, Pabinger, Lothaller & Geissler tracks 25 countries over 17 years and found that patients under 65 now make up >50% of all procedures - up from ~37% in 2005.
Read for free: oarsijournal.com/article/S10…
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#New this month our #Basic #Science Editor's Choice for #June.
PAR2 in bone accelerates late-stage OA, showing bone turnover’s key role in joint damage and the age- and cell-specific complexity of PAR2. #Osteoarthritis #BoneHealth
Read more 🔗: sciencedirect.com/science/ar…
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🔥 New in this month's special issue!
For osteoarthritis interventions to work long-term, we have to stop treating exercise as just a "treatment" and start focusing on behavior change theory to build sustainable habits.
Read more from Pellegrini et al: oarsijournal.com/article/S10…
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📉 High placebo response is a major hurdle in knee osteoarthritis trials.
A new study shows that Screening Period Pain Inconsistency when a patient's pain worsens right before randomization strongly predicts a massive, long-term placebo response.🔬
oarsijournal.com/article/S10…
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Does adding exercise therapy to a splint improve outcomes for thumb CMC osteoarthritis?
Read more in this month's issue that compared compared orthosis exercise against orthosis-only: oarsijournal.com/article/S10…
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🔬 Are we overcomplicating inclusion criteria for knee OA trials?
We often screen heavily for patellofemoral structural damage & bone marrow lesions (BMLs) assuming they accelerate overall cartilage loss.
But does the data actually back this up - oarsijournal.com/action/show…
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Can hsCRP help us identify an "inflammatory phenotype" in knee osteoarthritis?
New data from the NIH-funded MOST Study (n=792) suggests the answer is likely no.
Read more from George et al. - oarsijournal.com/article/S10…
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🦴Is waiting for knee replacements (TKR) slowing down drug discovery?
Using intermediate endpoints might make trials faster:
🔹CKOASO: Cuts sample size from 3,000 to 229
🔹esKOA: Strongest predictor of future TKR (5.7RR)
🔹FNIH: High feasibility
doi.org/q5p8
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⏰ ICYMI
Special issue on OA and obesity deadline has been extended to Jun 1 2026.
More information can be found here: sciencedirect.com/special-is…
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The way we talk about OA matters. 🦴
"Wear and tear" feels final, but OA is about resilience and movement. Our latest editorial highlights 4 metaphors from our 2025 competition to redefine the OA narrative.
Which one resonates with you? 👇
oarsijournal.com/article/S10…
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Therapeutics given to the knee joint are rapidly cleared. In this work, Boyer et al. engineered a cationic Interleukin-1 Receptor Antagonist (catIL-1RA) to target anionic cartilage and form drug depots within the joint.
Read more:
oarsijournal.com/article/S10…
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The incidence of #OA is higher is postmenopausal #women compared to aged matched #men...
Chen et al. links the osteoclast secreted galectin-3 to articular cartilage degeneration in rats!
Check out this work 📑 :
oarsijournal.com/article/S10…
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#ACL injury initiates #PTOA via two distinct processes: initial injury of the cartilage surface and secondary joint instability. Takahata et al. aimed to reveal the individual effects of cartilage compression and joint instability on PTOA progression.
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oarsijournal.com/article/S10…
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Live from the OARSI Word Congress 2026 in Florida! 🌴☀️
Did you know that all papers submitted to OAC undergo statistical review?
Rigorous and time-consuming, but very important.
Led by the amazing team of Jamie Collins Robin Christensen and Aleksandra Turkiewicz
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🗞️Today's Headline🗞️
Preventing osteoarthritis after ACL injury: The case for targeting pre-osteoarthritis illness
@OACJournal @Harkey_MS @jbdriban @AIRLabsMSU @oaactionallianc @OAClinicalRes
pubmed.ncbi.nlm.nih.gov/4139…
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Live from the OARSI Word Congress 2026 in Florida! 🌴☀️
OARSI President @dr_englund highlighting the top reviewers for OAC at his opening address 🥳
Augustin Latourte
André Struglics
Rachel E. Miller
Dr Thomas Perry
Alice Courties
Matthew Harkey
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We are just 2 DAYS away! Can't wait to see you at #OARSI !
Getting geared up for OARSI?🤩
Mark your calendars for the OAC/OAC Open Journal Session on April 23rd, 2026 11 am-12:30 pm EST. 🌴
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