Laboratory of timing, oscillations and patterns at EPFL
Joined March 2019
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28 Photos and videos
How does the segmentation clock instruct cells to form a somite boundary? Read our new pre-print “Clock driven waves of Tbx6 expression prefigure somite boundaries”, by @Olivier_Venzin and colleagues, to find out.
biorxiv.org/content/10.1101/…
Summary thread below: 1/15
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2. The segmentation clock forms a densely connected network. We show here that, in addition to driving oscillations of dpErk activity (Simsek et al. 2023) and inhibiting the expression of ripply1/2 (Yabe et al. 2023), Hes/Her genes also drive oscillations of Tbx6.
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We thank @chloe_jollivet, @nKiaru, @ORSPF, Clément Helsens, Luis G. Morelli and Koichiro Uriu for their great work, @GValentinEPFL and members of the Oates lab for their feedback and @ViventisMicro for their technical support.
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But, what are the cells doing? Our step by step guide to following single cells in vivo is now out (in collaboration with @nKiaru) 🔬
4 Jun 2023
But, what are the cells doing? Image Analysis pipeline to follow single cells in the zebrafish embryo biorxiv.org/cgi/content/shor… #bioRxiv
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Our collaborative work with @mssakar on a robotic microsurgery platform to investigate the mechanics of zebrafish embryo elongation.
9 Jan 2023
News article on our microsurgery platform. Please contact us if you would like to operate on your samples using our robot or build your own system. @eceozelci @OatesLab @NatureComms actu.epfl.ch/news/a-robotic-… #epfl
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oaties retweeted
26 May 2022
Excited to build on the footsteps of hugely #interdisciplinary mentors @StephanGrill @mpicbg @oateslab @epflsv as I make the transition to @TIFRScience as a group leader in September. 1/n
tifr.res.in/~dbs/faculty.htm…
symmetrylab.squarespace.com
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The final version of our manuscript, where we investigate emergence of left-right symmetric somites in #zebrafish embryos is now out!
nature.com/articles/s41586-0…
@Sundar_Ram_07 @mpopov1c @AOates1 @EPFL_en @epflSV
Is left-right #symmetry a default state in somites? Excited to share our latest #preprint that counters the textbook view
@Sundar_Ram_07 @mpopov1c @AOates1
biorxiv.org/content/10.1101/…
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Many thanks to the amazing colleagues @OatesLab, @LeBIOP for phenomenal support & the incredible fish facility @EPFL_en
Special thanks to @EbisuyaMiki @XavierTrepat for the news and views piece on the article
nature.com/articles/d41586-0…
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