OpenWorm is an open science project dedicated to creating the first digital organism, a C. elegans nematode. Get involved at openworm.org

Joined December 2010
237 Photos and videos
In 1986, John White published "The Mind of a Worm," the first complete wiring diagram of any animal's brain. 7,000 synapses, mapped by hand. This year, he was awarded the @WileyGlobal Prize in Biomedical Sciences. He's donating his share to @OpenWorm.
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We're organizing 2026 around: 29 Design Documents specifying how to model C. elegans, under scientific review A contributor progression model (Observer to Maintainer) AI-assisted contribution pathways The science is human-led. The scaling is AI-augmented.
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This is the largest single donation in OpenWorm's history. We won't waste it. Full announcement 2026 plans: openworm.tumblr.com/post/815…

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6 Feb 2024
Now streaming: OpenWorm interview on the @DataSkeptic podcast open.spotify.com/episode/4Re…
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6 Jul 2023
A major obstacle to modeling the nervous system of the worm has been the unknown weights of the connections. Which are excitatory or inhibitory and how strong? Well, the lab of @AndrewLeifer has put out a Neural Signal propagation atlas to address this critical gap (1/4)
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6 Jul 2023
Bravo to all the authors! (4/4)
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OpenWorm retweeted
1 Jun 2022
Fun to interactively play on the @OpenWorm site with our best mapped nervous system yet, and to think about building a virtual organism: opensourcebrain.org/projects…

1 Jun 2022
Excited about the publication of our state-of-the-art 3D neuron atlas of #Celegans, the world's cutest worm. It's crazy how much smarts it gets from just 302 neurons! bmcbioinformatics.biomedcent…
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30 Jun 2023
Promising resource from the Flavell lab with freely moving whole-brain calcium imaging datasets: wormwideweb.org/

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OpenWorm retweeted
Omg @YeminiLab. The White Knight of neuron identification. As designated by Keynote Speaker Oliver Hobert. And well deserved moniker too. Go NeuroPAL! #Worm23

ALT White Knight GIF

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OpenWorm retweeted
How friendly is worm community? We converged on finding w Cohen and Emmons lab. Papers came out together (below). Started Glasgow #Worm23 w stimulating discussions over haggis pizza w Netta Cohen to discuss collaborations 1) nature.com/articles/s41586-0… 2) nature.com/articles/s41586-0…
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OpenWorm retweeted
All winning entries of the #wormart at #Worm23 @GeneticsGSA. Wait until the end for a QR code for all entries. @foodskop started Art show in 1997. Do tag the winners/participants & RT. @chud8 @VarshaS53228024 @wormsense
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OpenWorm retweeted
A long shot, but are any of the authors on the RF diffusion paper following me, and would be willing to chat?
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