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With this week's #PeerReviewWeek theme ‘Innovation and Technology in Peer Review’ we’re curious to know what kinds of innovations you think would most improve the peer review process?
#PeerReviewWeek is here! For an overview of this week's events from @PeerRevWeek, and quick access to PLOS peer review resources, check out our latest post on The Official PLOS Blog: plos.io/4et8UAl
"As we embark on this transformative journey, we invite our readers, authors, researchers, and clinicians across disciplines to join us in shaping the future." Discover how we're expanding our horizons: plos.io/4cvPdX6
We're excited to introduce a revised scope for @PLOSPathogens! Read the scope updates, see details on how we've broadened our article formats for submission, and more in our latest Editorial: plos.io/4cvPdX6.
In this recent article, researchers from @i2sysbio share results that reveal common patterns of receptor usage among viruses, suggesting that enveloped viruses tend to use a broader repertoire of alternative receptors than non-enveloped viruses: plos.io/3PpAWSB
ALT Fig 3. Series of graphs depicting predictability of virus receptors. See the full caption at: https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1012021
Kicking sleepers out of bed: Macrophages promote reactivation of dormant Cryptococcus neoformans by extracellular vesicle release and non-lytic exocytosis: plos.io/3tufvbk
ALT Fig 1. VBNC cells promote a reduced and specific transcriptional response in murine bone marrow-derived macrophages (BMDMs).
Full caption here: https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1011841
🔎 A sticky situation: When trypanosomatids attach to insect tissues: plos.io/487ZIxR
ALT Fig 1. Diagrams of trypanosomatids in their motile and attached forms.
The large dark oval is the nucleus. The small dark disk is the kDNA. Green is the axoneme. Attachment plaques are shown as green lines in attached forms. A detailed description of swimming morphologies can be found in [15]. In monoxenous parasites and Leishmania spp., the attachment plaque forms at the tip of the shortened flagellum. In T. cruzi, the attachment plaque is also found at the tip but the flagellum is only slightly shorter. In T. brucei and T. congolense, the attachment plaque(s) form on the lateral portion of the flagellum.
Kicking sleepers out of bed: Macrophages promote reactivation of dormant Cryptococcus neoformans by extracellular vesicle release and non-lytic exocytosis: plos.io/3tufvbk
ALT Fig 1. VBNC cells promote a reduced and specific transcriptional response in murine bone marrow-derived macrophages (BMDMs).
Full caption here: https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1011841
🔎 A sticky situation: When trypanosomatids attach to insect tissues: plos.io/487ZIxR
ALT Fig 1. Diagrams of trypanosomatids in their motile and attached forms.
The large dark oval is the nucleus. The small dark disk is the kDNA. Green is the axoneme. Attachment plaques are shown as green lines in attached forms. A detailed description of swimming morphologies can be found in [15]. In monoxenous parasites and Leishmania spp., the attachment plaque forms at the tip of the shortened flagellum. In T. cruzi, the attachment plaque is also found at the tip but the flagellum is only slightly shorter. In T. brucei and T. congolense, the attachment plaque(s) form on the lateral portion of the flagellum.
How are we meeting our #OpenScience initiatives at PLOS Pathogens? Learn more from our editors in this latest editorial: plos.io/3R1vZ2n
ALT "As a leader in the field, PLOS Pathogens strives to advance community-rotted adoption of Open Science practices that enable transparency, rapid communication, reproducibility, and trust in research."
Check out our latest study in @PLOSPathogens where we explore hidden strategies for the subversion of host translation by the potyvirus TuMV in Arabidopsis.
journals.plos.org/plospathog…
🔎 Coinfections in the lung: How viral infection creates a favorable environment for bacterial and fungal infections: plos.io/3nLHVLf
ALT Fig 1. Graphic of the major physiologic and immunologic consequences from viral infection found to be involved in secondary bacterial susceptibility described in [4].
Created with BioRender.com. Read the full caption: https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1011334
In this study, researchers report the discovery of high levels of the anti-immune subgenomic flaviviral RNA (sfRNA) in dengue virus 2-infected mosquito saliva: plos.io/3u9yCHv
ALT Fig 6. Model: sfRNA in salivary vesicles is transported into cells to enhance infection at the biting site.
sfRNA packaged inside extracellular vesicles in infectious mosquito saliva is transferred to human skin cells during biting. sfRNA inhibits the antiviral innate immune response (interferon (IFN) system) to enhance skin cell virus infection. Created with BioRender.com.
How are we working towards our mission to advance community-rooted adoption of #OpenScience practices in pathogens research? Our editors discuss current initiatives in our latest editorial: plos.io/3R1vZ2n