Joined June 2011
- Tweets 687
- Following 109
- Followers 56
- Likes 930
9 Photos and videos
Shannon Pendergrast retweeted
3 Oct 2023
Check out yesterday’s @endpts article from @ky_lahucik featuring an interview with our new CEO, John Lepore, to learn how our ability to identify drug targets from previously unknown proteins enables us to develop new medicines. endpts.com/flagship-poaches-…
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Shannon Pendergrast retweeted
2 Oct 2023
We're thrilled to welcome John Lepore as our CEO! John brings two decades of experience in #drugdiscovery and development, and we look forward to his leadership as we pioneer the expanded human #proteome: ow.ly/mNNl50PRQ4k
#innovation #FlagshipFounded
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Shannon Pendergrast retweeted
13 Oct 2022
We get requests all the time for classic PokerXFactor training videos so we figured we'd start to put them online. Up first is Eric "Sheets" Haber's (@sheetspwns & @truedfs) very 1st PXF video on how to own poker sit-n-goes. Many more to come. Enjoy. youtu.be/2-A6k4AdOx4
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Shannon Pendergrast retweeted
21 Sep 2022
Illuminate the expanded #humanproteome with us! #BeProFound #NowHiring
We challenge assumptions & welcome different points of view as we aspire to make a profound impact on #humanhealth. #biotechjobs #STEMcareer #NowHiring #FlagshipFounded
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Shannon Pendergrast retweeted
19 Aug 2022
Are you a pioneer & a rule-breaker?
Then Get on a rocket ship!
#hiring #COOP #internship @ProFoundTx @FlagshipPioneer
profoundtx.com/jobs?gh_jid=6…
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Shannon Pendergrast retweeted
23 Jun 2022
ProFound™ Therapeutics was founded on the belief that "proteomic dark matter" exist.
Through the creation of the ProFoundry™ Atlas, our founders began to explore the white space of proteomics & unearthed several observations, impacting our understanding of biology & disease.
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Shannon Pendergrast retweeted
15 Jun 2022
The new protein factors & targets we've revealed using the ProFoundry™ Platform span a diversity of therapeutically impactful functional classes.
Explore how & why we're building on these foundational insights to generate new medicines. #genomicmedicine #geneticdisease
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Shannon Pendergrast retweeted
13 Jun 2022
We asked, "What if the human proteome is larger than imagined?"
If true, it would represent a paradigm shift in biology & reveal a universe of novel therapeutic targets. @FlagshipPioneer's @NoubarAfeyan discusses how these insights will unlock the next biotech revolution.
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Shannon Pendergrast retweeted
2 Oct 2021
6 years ago I joined a 20-person startup.
I wanted to quit after my first week, but I didn't.
Now our company is worth over $1B and has 200 employees.
Here's what I've learned about succeeding at a startup:
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Shannon Pendergrast retweeted
29 Mar 2021
DNA-encoded library technology has the potential to revolutionize drug discovery. Join us for this discussion as well as other programs we have coming up. Discover: jji.jnj/38ToK7d
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Shannon Pendergrast retweeted
19 Mar 2021
PADs: World’s most under-appreciated targets. (Disclosure: I am totally biased.)
19 Mar 2021
Excited to be a part of this new study supporting PAD2 as a therapeutic target in lung fibrosis: "Citrullinated vimentin mediates development and progression of lung fibrosis" stm.sciencemag.org/content/1…
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Shannon Pendergrast retweeted
17 Mar 2021
ARMMs particles are a unique class of #extracellularvesicles that are naturally produced by cells and serve as a vehicle to package and deliver communication signals, including transcription complexes, between cells and tissues. - @vesigen_tx exosome-rna.com/vesigen-ther…
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Shannon Pendergrast retweeted
9 Mar 2021
"If you take urine from a patient at different points in time and measure #mRNA from inside #microvesicles, you get the same signature over time, allowing you to assess whether or not the transplant is being rejected.” - @BrighamWomens - @harvardmed exosome-rna.com/novel-urinar…
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Shannon Pendergrast retweeted
4 Mar 2021
Interesting! I’ve always worried that by overselecting your #extracellularvesicle population you may be missing the good biomarkers.
People strive for ‘pure’ but we should always be asking - what’s the best biofluid subfraction for the disease scenario? It might not even be EVs!
4 Mar 2021
Tetraspanin immunocapture phenotypes extracellular vesicles according to biofluid source but may limit identification of multiplexed cancer biomarkers biorxiv.org/cgi/content/shor… #bioRxiv
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Shannon Pendergrast retweeted
12 Feb 2021
Cytoskeleton of a #podocyte as seen through a microscope: From widefield to #superresolution 3D-SIM to dSTORM. Acquired on our @zeiss_micro Elyra PS.1 #FluorescenceFriday
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Shannon Pendergrast retweeted
3 Feb 2021
This drug could be a milestone. Why? Because it’s the first small molecule to work by targeting RNA rather than proteins. Read our analysis nature.com/articles/s41587-0…
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Shannon Pendergrast retweeted
23 Jan 2021
New Research: microRNA-155 Is Decreased During Atherosclerosis Regression and Is Increased in Urinary Extracellular Vesicles During Atherosclerosis Progression: Background Atherosclerosis is a chronic inflammatory disease driven by macrophage… frontiersin.org/articles/10.… #immunology
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Shannon Pendergrast retweeted
Donating samples to a biobank will speed up research which may benefit future patients. Dr Sarah McGarrigle #biobanking2021 #TSJCI #WorldCancerDay #IAmAndIWill #TSJCIResearch
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