Joined May 2022
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Vanderbilt senior Lauren Friedman (@lololizzle) recently spoke at the MAHA Mental Health & Overmedicalization Summit about living with Post-SSRI Sexual Dysfunction (PSSD). Her testimony highlighted the urgent need for recognition, research, and treatment for the condition.
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(1/2) We just received a response to a freedom of information request made the @US_FDA. The FDA Adverse Event Reporting System (FAERS) had 246 cases of “post 5-alpha-reductase inhibitor syndrome” under the MedDRA code 10082430 as of June 3, 2026. 15 cases resulted in fatalities.
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(2/2) Below is the year-by-year breakdown of fatal cases of "post-5-alpha-reductase inhibitor syndrome" that were reported under the MedDRA code 10082430.
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We have received a response to a freedom of information request made to the @US_FDA. The FDA Adverse Event Reporting System (FAERS) had 585 cases of the MedDRA term "post-SSRI sexual dysfunction" (MedDRA code 10086208) as of June 3, 2026. None of these cases are listed as fatal.
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PSSD Network | Post-SSRI Sexual Dysfunction retweeted
First Major Article on PSSD in Spanish Published A major article on PSSD has just been published in El País, one of the most prestigious newspapers in the Spanish speaking world. The idea that PSSD is confined to English speaking countries becomes increasingly difficult to sustain as awareness grows internationally. One passage from the article captures the condition particularly well: "Sexuality is not just sexual intercourse; sexuality is much more than that. It is holding someone's hand, wanting to hug your partner, a smile in the midst of suffering, or reading a book together by the seaside. It is also important at the level of energy and vitality. A great deal of one's life drive is lost."
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We just received a response to a freedom of information request made to the Norwegian Medical Products Agency. There were 7 patients in Norway who reported PSSD and PGAD. Their answer is unclear about how exactly how many cases of each condition were reported.
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PSSD Network | Post-SSRI Sexual Dysfunction retweeted
SSRI DRUG PERMANENT EFFECTS 👇 instagram.com/reel/DZLmZKoud…
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PSSD Network | Post-SSRI Sexual Dysfunction retweeted
“I have no sensation in my genitals. My clitoris is completely numb.” Lauren Friedman, 23, shared her devastating experience with PSSD (Post-SSRI Sexual Dysfunction) — permanent loss of libido, sensation, and ability to orgasm after taking antidepressants. Chris Williamson and Isabel Brown reacted with shock, noting how little mainstream coverage this issue receives. Sexual side effects from SSRIs affect 50-70% of users. For a subset of people, these effects (including genital numbness and anorgasmia) persist long after discontinuation, a condition known as Post-SSRI Sexual Dysfunction (PSSD). The exact prevalence is unknown, but patient reports and emerging research suggest it may be under-recognized. People deserve full informed consent about potential long-term risks before starting these medications. What do you think, should PSSD get more public and medical attention?
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PSSD Network | Post-SSRI Sexual Dysfunction retweeted
💊PSSD is a life-altering nervous system injury induced by taking an antidepressant 💊Cases have been reported after short-term exposure and even after a single dose. ➡️ for more info check out @PSSDNetwork
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PSSD Network | Post-SSRI Sexual Dysfunction retweeted
Do SSRIs have chemical effects on male sperm? -Yes. This NEW review focuses on animal studies & shows that SSRIs: 1.⬇️sperm number 2.⬆️malformations 3.⬆️DNA damage 4.⬇️sperm motility And this has also been shown in HUMAN studies (next tweet..) (1/2) academic.oup.com/smr/article…
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PSSD Network | Post-SSRI Sexual Dysfunction retweeted
After stopping antidepressants, this 23-year-old said she experienced a “chemical castration." What to know about PSSD, according to experts. usatoday.com/story/life/heal…
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PSSD Network | Post-SSRI Sexual Dysfunction retweeted
I believe the side effects of psych meds are worse than anyone could have imagined. Protracted withdrawal, PSSD, crippling anxiety and insomnia, akathisia....and many others. This is an absolute scandal.
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PSSD Network | Post-SSRI Sexual Dysfunction retweeted
"In a bustling ballroom in an upscale hotel, Laura Friedman, 23, sat onstage to talk about her sex life. Specifically, sexual dysfunction. The Vanderbilt University senior explained that after stopping antidepressants, she experienced what she described as a 'chemical castration,' with complete loss of feeling in her genitals. She’s also lost her sense of emotional connection. 'I can't feel love for my own mother, which is the hardest thing on Earth.'" #antidepressants #PSSD ARTICLE LINK: buff.ly/o6dqLlu
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PSSD Network | Post-SSRI Sexual Dysfunction retweeted
We need better informed consent and more thoughtful use of these drugs that can lead to enduring sexual, physical, and emotional dysfunction after stopping the drug. #PSSD, #PFS, #PAS. @CorewellHealth @BeaumontUrology usatoday.com/story/life/heal…
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PSSD Network | Post-SSRI Sexual Dysfunction retweeted
After stopping antidepressants, this 23-year-old said she experienced a “chemical castration." What to know about PSSD, according to experts. usatoday.com/story/life/heal…
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PSSD Network | Post-SSRI Sexual Dysfunction retweeted
Last month, @SecKennedy launched a bold action plan to curb psychiatric overprescribing. The national conversation has begun.
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“We really don't have good data on that because all the money to study things like that comes from the pharmaceutical industry, and they're not going to fund studies that put the profits of their products in jeopardy.” David Wayne (@DescribeHealth) on the prevalence of PSSD.
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You can watch the full interview of David Wayne (@DescribeHealth) by @MaryBowdenMD, titled “Psych Med Fraud,” below: x.com/MaryBowdenMD/status/20…

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“You probably won't be surprised to know that almost all federal regulators around the world acknowledge this side effect, but our FDA does not, of course. And it's quite scandalous.” David Wayne (@DescribeHealth) mentions the @US_FDA still doesn't require any warnings for PSSD.
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You can watch the full interview of David Wayne (@DescribeHealth) by @MaryBowdenMD, titled “Psych Med Fraud,” below: x.com/MaryBowdenMD/status/20…

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We just received a response to a freedom of information request made to the Ministry of Health of Azerbaijan. There were no patients in Azerbaijan who reported PSSD, PFS or PGAD.
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