Psychoradiology is an open access journal which aims to bridge the gap between neuroscientists and clinicians.
Joined August 2020
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303 Photos and videos
Jun 12
x.com/PSYRAD2/status/2064029…
🌟Key Take-aways:
-Disruptions span from faulty bodily awareness to a blurred self–other boundary and disconnected narrative identity.
-The core pathology lies in the failure to integrate self-related information across different hierarchical levels.
#ASD
Jun 8
🚨NEW paper in @Psychoradiology!
This systematic review synthesizes findings from 49 fMRI and sMRI studies to explore the neural mechanisms of atypical self-awareness in ASD through a three-level hierarchical model.🚀
🔗: doi.org/10.1093/psyrad/kkag0…
#ASD #MRI #SocialCommunication
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Jun 11
x.com/PSYRAD2/status/2064029…
📉ASD is characterized by a systemic failure to integrate information across the neural hierarchy:
- Bottom-up Disruption: Foundational sensory and bodily signals are poorly processed, leading to sensory overload.
#MentalHealth #AutismSpectrumDisorder
Jun 8
🚨NEW paper in @Psychoradiology!
This systematic review synthesizes findings from 49 fMRI and sMRI studies to explore the neural mechanisms of atypical self-awareness in ASD through a three-level hierarchical model.🚀
🔗: doi.org/10.1093/psyrad/kkag0…
#ASD #MRI #SocialCommunication
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Jun 11
- Top-down Disconnection: Higher-order mental networks fail to effectively regulate and integrate atypical sensory inputs.
- Fragmented Experience: This cross-level breakdown results in a profound disconnect between the body, environment, and mind.
🔗:doi.org/10.1093/psyrad/kkag0…
#ASD
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Jun 10
x.com/PSYRAD2/status/2064029…
🧠🌐This review highlights how ASD impacts three distinct neural levels of self-representation:
1. Interoceptive Self: An "unstable foundation" in the insula and thalamus, leading to atypical bodily and affective awareness.
#ASD #MRI #MentalHealth
Jun 8
🚨NEW paper in @Psychoradiology!
This systematic review synthesizes findings from 49 fMRI and sMRI studies to explore the neural mechanisms of atypical self-awareness in ASD through a three-level hierarchical model.🚀
🔗: doi.org/10.1093/psyrad/kkag0…
#ASD #MRI #SocialCommunication
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Jun 10
2. Exteroceptive Self: A "blurred boundary" in the TPJ and mPFC, resulting in impaired self–other differentiation.
3. Mental Self: An "isolated hub" where the integration of cortical midline structures (ACC/PCC) is fundamentally compromised. 🧠🌐
🔗: doi.org/10.1093/psyrad/kkag0…
#ASD
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Jun 10
x.com/PSYRAD2/status/2064029…
💡To explore the neural basis of self-processing in ASD, this review:
🔹Identified human neuroimaging studies (2000–2025) on the neural basis of self-related processing in ASD.
🔹Explicitly guided by a three-level hierarchical model.
#ASD #MentalHealth
Jun 8
🚨NEW paper in @Psychoradiology!
This systematic review synthesizes findings from 49 fMRI and sMRI studies to explore the neural mechanisms of atypical self-awareness in ASD through a three-level hierarchical model.🚀
🔗: doi.org/10.1093/psyrad/kkag0…
#ASD #MRI #SocialCommunication
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Jun 8
🚨NEW paper in @Psychoradiology!
This systematic review synthesizes findings from 49 fMRI and sMRI studies to explore the neural mechanisms of atypical self-awareness in ASD through a three-level hierarchical model.🚀
🔗: doi.org/10.1093/psyrad/kkag0…
#ASD #MRI #SocialCommunication
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Jun 4
x.com/PSYRAD2/status/2061791…
🌟Key Take-aways:
-Thalamo-visual dysconnectivity is a robust schizophrenia feature scaling with clinical symptom severity.
-Integrating functional, structural, and molecular data clarifies understanding of information-processing failures.
#MultimodalMRI
Jun 2
🚨New research (Cheng Luo et al)!
👁️This multimodal MRI study reveals widespread impaired connectivity between the thalamus and both the dorsal and ventral visual pathways in patients with schizophrenia.
New targets for non-invasive treatment.🚀
🔗:doi.org/10.1093/psyrad/kkag0…
#fMRI
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Jun 4
x.com/PSYRAD2/status/2061791…
Results:
✅Patients showed significantly decreased neural activity and widespread connectivity alterations in dorsal and ventral visual pathways
✅Altered mediation effects were found in the thalamo-dorsal pathway, specifically involving MT, V1, V2, and V3
Jun 2
🚨New research (Cheng Luo et al)!
👁️This multimodal MRI study reveals widespread impaired connectivity between the thalamus and both the dorsal and ventral visual pathways in patients with schizophrenia.
New targets for non-invasive treatment.🚀
🔗:doi.org/10.1093/psyrad/kkag0…
#fMRI
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Jun 4
✅These neural abnormalities were closely related to disease duration, positive symptom severity, and specific neurotransmitter densities.
🔗: doi.org/10.1093/psyrad/kkag0…
#Schizophrenia #fMRI #MultimodalMRI #Thalamus
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Jun 3
x.com/PSYRAD2/status/2061791…
📊To investigate these disruptions, this study used multimodal MRI and neurotransmitter mapping:
🔹Data: Acquired resting-state fMRI, task-state fMRI, and DTI data.
🔹Evaluated neural activity, FC,SC, and structure–function coupling.
#fMRI #Thalamus
Jun 2
🚨New research (Cheng Luo et al)!
👁️This multimodal MRI study reveals widespread impaired connectivity between the thalamus and both the dorsal and ventral visual pathways in patients with schizophrenia.
New targets for non-invasive treatment.🚀
🔗:doi.org/10.1093/psyrad/kkag0…
#fMRI
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Jun 4
🔹 Clinical Link: Correlated altered imaging parameters with disease duration and symptom severity.
🔹 Molecular Analysis: Mapped spatial associations between brain activity and neurotransmitter receptor/transporter distributions.
🔗: doi.org/10.1093/psyrad/kkag0…
#Schizophrenia #fMRI
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Jun 2
x.com/PSYRAD2/status/2061791…
💡This study explores how disrupted thalamo-visual circuits drive schizophrenia symptoms:
-The specific relationship between the thalamus and dorsal/ventral visual regions in Schizophrenia remains unclear.
🔗: doi.org/10.1093/psyrad/kkag0…
#Schizophrenia #fMRI
Jun 2
🚨New research (Cheng Luo et al)!
👁️This multimodal MRI study reveals widespread impaired connectivity between the thalamus and both the dorsal and ventral visual pathways in patients with schizophrenia.
New targets for non-invasive treatment.🚀
🔗:doi.org/10.1093/psyrad/kkag0…
#fMRI
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Jun 2
🚨New research (Cheng Luo et al)!
👁️This multimodal MRI study reveals widespread impaired connectivity between the thalamus and both the dorsal and ventral visual pathways in patients with schizophrenia.
New targets for non-invasive treatment.🚀
🔗:doi.org/10.1093/psyrad/kkag0…
#fMRI
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May 30
🧠This review maps the White Matter functional connectome, highlighting its reliability in predicting intelligence and identifying inter-subject variability.🚀
🔗: doi.org/10.1093/psyrad/kkaf0…
#rsfMRI #WhiteMatter #Neuroimaging #BrainConnectome
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May 30
x.com/PSYRAD2/status/2058905…
🧠Key Take-aways:
-Increased Brain-PAD is a robust quantitative marker for the conversion from subthreshold depression to full MDD
-Brain age could facilitate early detection and help guide interventions targeting brain health in high-risk individuals
#MDD
May 25
🚨 New research in @psychoradiology (Ruibin Zhang et al., 2025)!
This study reveals that accelerated brain aging (Brain-PAD) serves as a stable, quantitative marker for predicting the progression from subthreshold depression to MDD. 🧠📉
#MDD #MachineLearning #Aging #UkBiobank
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May 30
New study on neurobiological markers of subthreshold depression progression found:
✅Individuals whose condition worsened to MDD showed significantly greater brain aging than those who recovered.
✅Higher Brain-PAD was significantly associated with increased MDD progression risk
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May 30
✅This association remained robust even after controlling for various biological and environmental covariates.
🔗: doi.org/10.1093/psyrad/kkag0…
#MDD #Depression #MachineLearning #Aging #UkBiobank
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May 30
x.com/PSYRAD2/status/2058905…
New research using UK Biobank and ML maps brain aging's link to depression progression:
🔹SVR model to calculate Brain-PAD
🔹Logistic regression to assess Brain-PAD’s stability as a predictor while adjusting for sex, lifestyle, and socioeconomic factors.📊
May 25
🚨 New research in @psychoradiology (Ruibin Zhang et al., 2025)!
This study reveals that accelerated brain aging (Brain-PAD) serves as a stable, quantitative marker for predicting the progression from subthreshold depression to MDD. 🧠📉
#MDD #MachineLearning #Aging #UkBiobank
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May 27
x.com/PSYRAD2/status/2058905…
- MDD is linked to accelerated brain aging, but research relies mainly on cross-sectional data.
- Brain aging's role in subthreshold depression progression remains unclear.
🌐This new study examines whether brain aging predicts depression's trajectory.
May 25
🚨 New research in @psychoradiology (Ruibin Zhang et al., 2025)!
This study reveals that accelerated brain aging (Brain-PAD) serves as a stable, quantitative marker for predicting the progression from subthreshold depression to MDD. 🧠📉
#MDD #MachineLearning #Aging #UkBiobank
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