@PapersAging profile picture
Aging Papers @PapersAging
Joined November 2023
  • Tweets 1,194
  • Following 29
  • Followers 14
Photos and videos
High Frailty Index Scores Predict Mortality and Changes in Blood-Based Biomarkers in Aging Female Mice academic.oup.com/biomedgeron…

High Frailty Index Scores Predict Mortality and Changes in Blood-Based Biomarkers in Aging Female...

Abstract. Variability in aging rates can be quantified with a frailty index (FI) based on the accumulation of clinically evident health deficits in aging m

academic.oup.com
Using case-mixes to understand health resource utilization trajectories among older adults at high risk of falls who received baseline geriatrician-based falls prevention clinic care academic.oup.com/biomedgeron…

Using case-mixes to understand health resource utilization trajectories among older adults at high...

AbstractBACKGROUND. We identified case-mixes among older adults at high risk of future falls, determined by longitudinal health resource utilization (HRU)

academic.oup.com
Effect of inactivation of the USP19 deubiquitinase gene in mice on important phenotypes of aging academic.oup.com/biomedgeron…

Effect of inactivation of the USP19 deubiquitinase gene in mice on important phenotypes of aging

Abstract. Aging is associated with many chronic conditions that increase morbidity and mortality. These include obesity, diabetes, sarcopenia, osteoporosis

academic.oup.com
Untargeted Metabolomics Reveals Effects of Calorie Restriction on Skeletal Muscle in Older Female and Male Rats academic.oup.com/biomedgeron…

Untargeted Metabolomics Reveals Effects of Calorie Restriction on Skeletal Muscle in Older Female...

Abstract. This study used untargeted metabolomics to investigate how calorie restriction (CR) affects skeletal muscle in older female and male rats. Fische

academic.oup.com
Interventions that prolong multidimensional indicators of healthspan in humans: a systematic review of randomised controlled trials academic.oup.com/biomedgeron…

Interventions that prolong multidimensional indicators of healthspan in humans: a systematic review...

AbstractBackground. Maximising healthspan, the period of life spent in good health, is a public health priority. This review aimed to summarise the current

academic.oup.com
1
Uric Acid to HDL-C Ratio as a Novel Biomarker for Sarcopenia: A National Study with Machine Learning Insights academic.oup.com/biomedgeron…

Uric Acid to HDL-C Ratio as a Novel Biomarker for Sarcopenia: A National Study with Machine...

AbstractBackground. Sarcopenia is a major age-related health burden. Although the uric acid to high-density lipoprotein cholesterol ratio (UHR) has been li

academic.oup.com
Examining the Relevance of Gait Speed Resiliencies to Different Stressors: the ARIC Study academic.oup.com/biomedgeron…

Examining the Relevance of Gait Speed Resiliencies to Different Stressors: the ARIC Study

AbstractBackground. Different stressors may impact physical resilience differently (resiliencies). Objective metrics assessing different stressors’ ‘releva

academic.oup.com
Turning as a single and dual task—associations with alzheimer’s and vascular pathologies in cognitively healthy older people academic.oup.com/biomedgeron…

Turning as a single and dual task—associations with alzheimer’s and vascular pathologies in...

AbstractBackground. Turning performance is an important and challenging motor activity, with potential relevance in several brain diseases. This study aime

academic.oup.com
1
Olfaction and Muscle Strength in Older Adults: A Longitudinal Study academic.oup.com/biomedgeron…

Olfaction and muscle strength in older adults: a longitudinal study

AbstractBackground. Olfactory impairment is common in older adults and has been linked to weight loss and functional decline. This study aimed to examine w

academic.oup.com
1
Developing and Internally Validating AI-Based Aging Resilience Biomarkers in Non-Human Primates academic.oup.com/biomedgeron…

Developing and internally validating AI-based aging resilience biomarkers in non-human primates

Abstract. Quantifying biological aging is crucial for understanding functional decline before the onset of morbidity. While many accelerated aging and frai

academic.oup.com
1
Frailty and genetics: linking molecular aging to clinical vulnerability academic.oup.com/biomedgeron…

Frailty and genetics: linking molecular aging to clinical vulnerability

Abstract. Aging is a multifactorial process involving cumulative cellular and molecular damage, directly affecting physiological reserve and homeostasis. I

academic.oup.com
3
Correction to: A genome-wide association study identified 10 novel genomic loci associated with intrinsic capacity academic.oup.com/biomedgeron…

Correction to: A genome-wide association study identified 10 novel genomic loci associated with...

This is a correction to: Melkamu B. Beyene, Renuka Visvanathan, Robel Alemu, Beben Benyamin, Rudrarup Bhattacharjee, Habtamu B. Beyene, Olga Theou, Matteo

academic.oup.com
1
Effects of a Short-Term Multicomponent Functional Exercise Program on the Serum Proteome: An Exploratory Study in Hospitalized Older Adults academic.oup.com/biomedgeron…

Effects of a short-term multicomponent functional exercise program on the serum proteome: an...

Abstract. Hospitalization in older adults often leads to disability in daily living activities, thereby increasing the risk of functional and cognitive imp

academic.oup.com
1
Immunosenescence and CMV-Associated Immune Signatures on SARS-CoV-2 Booster Responses academic.oup.com/biomedgeron…

Immunosenescence and cytomegalovirus-associated immune signatures on severe acute respiratory...

Abstract. Aging remodels antiviral immunity, yet its influence on responses to repeated mRNA vaccination is not fully defined. We evaluated humoral and sev

academic.oup.com
1
The Crossroads between Osteosarcopenia and Intrinsic Capacity — A Narrative Review academic.oup.com/biomedgeron…

The crossroads between osteosarcopenia and intrinsic capacity—a narrative review

Abstract. Intrinsic capacity (IC) is defined as the composite of physical and mental abilities an individual possesses, encompassing 5 domains: cognition,

academic.oup.com
2
Predicting One-Year Mortality in Older Cancer Patients: Performance of G8, SPPB, and IF-VIG in the PROFIT Study academic.oup.com/biomedgeron…

Predicting 1-year mortality in older cancer patients: performance of G8, SPPB, and IF-VIG in the...

AbstractBackground. Frailty is a prognostic determinant in older patients, yet the most effective tools to predict survival remain unclear. This study aime

academic.oup.com
1
Glycemic Control Targets in Older Adults with Type 2 Diabetes and Chronic Kidney Disease: A Trajectory-Based Survival Analysis of HbA1c academic.oup.com/biomedgeron…

Glycemic control targets in older adults with type 2 diabetes and chronic kidney disease: a...

AbstractBackground. The optimal glycemic target for older adults with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD) remains controversia

academic.oup.com
1
Hot flashes, cold feet: a cautious embrace of regulatory reform academic.oup.com/biomedgeron…

Hot flashes, cold feet: a cautious embrace of regulatory reform

On November 10, 2025, the U.S. Food and Drug Administration (FDA) announced the removal of boxed warnings from most systemic and low-dose vaginal estrogen-

academic.oup.com
1
Relative Impact of Multidomain Lifestyle Interventions on Deficit Accumulation Frailty Over 24 Months in the U.S. POINTER Trial academic.oup.com/biomedgeron…
1
Time-restricted feeding improves metabolic flexibility, promotes beiging, and mitigates fibro-inflammation in the adipose tissue of aged mice academic.oup.com/biomedgeron…

Time-restricted feeding improves metabolic flexibility, promotes beiging, and mitigates fibro-inf...

Abstract. Adipose dysfunction contributes to age-related systemic decline primarily through its adverse effects on energy metabolism, insulin sensitivity,

academic.oup.com
1
Load more