We are collecting cool Pathology spotters & cases in one place. If you have one, tag us. We will feature you! #pathspotter #pathtwitter

Joined May 2020
11 Photos and videos
PathSpotters retweeted
Primary localized amyloid of the breast #breastpath #PathTwitter #MedTwitter #pathology 🍏Detected on screening mammography as clusters of calcifications 🍏 25% do not develop a hematologic disorder or systemic amyloidosis 🍏Apple-green on polarized light
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Xanthoma
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Balloon Cell Melanoma
Balloon Cell Melanoma: 🔬Rare variant of MM in which cells have abundant clear cytoplasm 🔬IHC: HMB45 ,S100 ,MelA 🔬DD: balloon cell nevi(lack atypia/mitosis),other clear cell tumors 🔬Prognosis: similar to other MM types @PathSpotters #PathTwitter #path #derm @ColumbiaPath
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Chronic necrotising aspergillosis
Chronic necrotising aspergillosis is locally invasive is seen in patients with immunodeficiency or chronic lung disease. Aspergilloma is a fungus ball that develops in a pre-existing cavity in the lung parenchyma. Acute angled dichotomous branching hyphae found in necrotic tissue
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Bronchiectasis
Replying to @HermelinMD
✅Bronchiectasis. In addition to respiratory complications, children also develop pancreatic insufficiency & lose the exocrine pancreas leading to malabsorption and steatorrhea, as well as GI complications. x.com/luishcruzc/status/1022…
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Warthin-like papillary thyroid carcinoma
Warthin-like papillary thyroid carcinoma. 🔬Papillae lined with oncocytic cells, with prominent lymphocytic infiltration of stalks. Tumor nuclei are enlarged, irregularly sized with grooves and occasional pseudo-inclusions. Background of lymphocytic thyroiditis.
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Dedifferentiated Chondrosarcoma
DEDIFFERENTIATED CHONDROSARCOMA. NB: juxtaposition of lower grade chondrosarcoma with an undifferentiated spindle-pleomorphic cell neoplasm; brisk mitotic activity; necrosis.
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Kikuchi-Fujimoto Disease
REtweet Kikuchi-Fujimoto disease. Necrosis without neutrophils, increased plasmacytoid dendritic cells, CD123 positive
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IgA Nephropathy
IgA nephropathy. HE, PAS, PAM and DIF(IgA). #pathology #pathology #nephropath
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Fibrous dysplasia of bone
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Aggressive NK/T cell leukemia
Aggressive NK/T cell leukemia. Gross and HE. #Pathology #Pathologist #Hemepath
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Lipoblastoma
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Mucinous metaplasia of the fallopian tube
Mucinous metaplasia of the fallopian tube - Can be associated with Peutz-Jeghers syndrome and mucinous neoplasms at other sites - Should exclude mucinous neoplasia elsewhere in female genital tract/GI #pathresidents #gynpath
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Nodular Melanoma
Nodular melanoma: large profusely bleeding “skin tag" present for 3 months in the intergluteal fold. Positive for S100, Melan A, and HMB 45.Classic features: dermal-invasive melanoma with lack of significant radial growth phase (i.e. junctional component)
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Metastatic Breast IDC with lobular growth pattern
Metastatic breast IDC with lobular growth pattern in the pleural cavity: Cytology showed abundant atypical cells with cannibalism. Cell blocks were positive for MOC31, GATA-3, GCFDP-15, and negative for mucicarmine, ER, PR, HER2.
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Multifocal Oncocytoma of Parotid
Multifocal oncocytoma/oncocytosis of parotid. 🔹multiple nodules, some circumscribed and some not. 🔹some can be clear cell rich. 🔹p63 should show an incomplete outer layer around the nests. But wait…aren’t these supposed to be golden brown grossly? See final pic.
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Solitary fibrous tumor/Hemangiopericytoma
Solitary fibrous tumor/Hemangiopericytoma, WHO grade I. Cerebrum, tumorectomy. HE and STAT6. #pathology #neuropath
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Epithelioid GIST
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