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Image Quiz!
A 41 year old woman underwent a core needle biopsy for a 3 cm breast mass discovered on her first screening mammogram. The lesional spindle cells show the CD68 immunostaining pattern seen below; they are also positive for ALK and negative for SMA and desmin. (Cont.)
Which of the following is the most likely diagnosis?
A. ALK positive histiocytosis
B. Erdheim-Chester disease
C. Extranodal Rosai-Dorfman disease
D. Inflammatory myofibroblastic tumor
E. Juvenile xanthogranuloma
Answer: buff.ly/3P3clm3#PathTwitter#PathologyOutlines
Mark your calendar for the Kameda Pathology Seminar, featuring Dr. Nat Pernick as a guest speaker, on December 25 at 18:00 JST! Participate online from anywhere or attend in person in Tokyo.
Register for online or onsite attendance: buff.ly/49OSeBC#Pathology#Tokyo
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Case of the Month: A 32 year old woman with a clinical history of complex partial type seizures underwent a brain MRI, which showed a 2 cm solid cystic lesion without contrast enhancement in the left temporal lobe.
Although the lesion remained stable over a 1 year follow up, the patient underwent surgery due to an increased frequency of seizures. The lesion was completely removed; the patient is in good health with no evidence of recurrence 1 year after surgery. What's your diagnosis?
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Dr. Thomasson was appointed to the Board (Transfusion Medicine). He is Asst. Prof. of Pathology & Laboratory Medicine at BU Chobanian & Avedisian School of Medicine, Assoc. Dir. of BMC's residency program, and Med. Dir. of BMC's Blood Bank & Transfusion Service.
(See comments)